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The map label for this gene is nrdD [H]

Identifier: 125623154

GI number: 125623154

Start: 267262

End: 269505

Strand: Direct

Name: nrdD [H]

Synonym: llmg_0281

Alternate gene names: 125623154

Gene position: 267262-269505 (Clockwise)

Preceding gene: 125623152

Following gene: 125623155

Centisome position: 10.57

GC content: 38.41

Gene sequence:

>2244_bases
ATGAAAACAGAAGTAAAATATCAAGATGTAACACTAGAAGAAATCAATGTTATAAAGCGTGATGGGCGCTCAGTAAAATT
TAATAGTGAGAAAATTTTTGATGCCTTGACTAAAGCGGCTAAAAAAGTAGAACTGACAGATAAATCAGTACTCTCAGAAC
TTACTGACAGAGTGGTCAGTGAGATTTTTAGTCGTTTTTCTGAAAATGTCAAAATTTATGAAATCCAATCCATTGTTGAA
CAAGAACTTCTGGAGTCTGGCGAAACAGCACTTGCTGAAGAATATATCTCTTATCGTGCCAATCGTGATTTAGCCCGCAC
CAAAGCGACAGATATCAATTTCACGATTGAAAAGTTAATCAACCGTGACCAAACTGTCGTTAATGAAAATGCCAATAAAG
ATTCTAACGTTTTCAATACTCAACGTGACTTGACTGCTGGGGCGGTTTCCAAAGCAATTGGTTTGAAACTCCTTCCCCCA
CATGTGGCAAATGCTCACCAAAAAGGCGATATTCATTATCATGACCTTGATTATAGCCCATTTACAACGATGGCTAACTG
TTGTTTGATTGACTTTAAAAATATGTTTGAAAATGGTTTTAAACTTGGAAATGCGCAAGTTGATTCGCCAAAATCCATTC
AAACAGCAACCGCTCAAGCCAGTCAAATTATCGCTAACGTGGCAAGTAGCCAATATGGTGGTTGTTCATTTGACCGTGCC
GATGAAGTTTTGGCCCCTTATGCCAAGTTAAACTATCAAAAACACTTAAAAGATGCTCAAAAATGGATTGATGGCGATGA
AAAACGCGAAGCTTATGCTCGTGAAAAAACAGCTAAAGATATCTATGATGCAATGCAATCTTTAGAATATGAAATTAATA
CTTTGTTCACTTCAAATGGTCAAACACCTTTTGTAACTGTTGGTTTTGGTTTAGGAGATGATTGGTATGCGCGTGAAATT
CAAAAAGCAATCTTAAAAGTACGGATTGGTGGTTTAGGTTCTGAGCACCGCACAGCCATTTTCCCTAAATTGATTTTCAC
ACTCAAACGTGGACTTAACCTTGAAGTAGGAACACCAAACTATGACATCAAAGAACTTGCCCTTGAATGTTCAACAAAAC
GCATGTACCCTGATATTTTGAGCTATGATAAAATTGTTGAATTAACAGGTTCATTTAAAGCTTCAATGGGTTGTCGTTCG
TTCTTGCAAGGTTGGAAAGATGCCAATGGTAATGACGTGACTGCTGGACGTAATAATCTTGGAGTTGTCACAGTCAACCT
GCCACGTATCGCTCTTGAAGCCGCTGGAAATAAAGAAAAATTCTGGGAAATTTTCAATGAACGTGTTGAAATTGCACATG
ATGCTCTTGCCTTTCGTGTGGAGCGTGCCAAAGAAGCACAACCTAAAAATGCACCAATTCTCTTTATGAATGGCGCTTTA
GGTCGTCTTGATTCGGAAGGTTCAGTAGATGACTTGTACAATAATGAACGTGCAACCGTAAGTTTGGGCTATATCGGACT
TTATGAAGTGGCTACCACTTTTTATGGTCCAACTTGGGAAAGTAATCCAGAAGCCAAAGCTTTTACCATTGAAATTGTCA
AACGTATGCACGAAGATTGCGAAGATTGGTCTAAAGCCTCAGGCTATCATTATTCTGTTTATTCAACACCATCAGAAAGT
TTAACTGACCGTTTCTGCCGAATGGACAAAGAAAAATTTGGTTCAGTGGCGGATATTACTGACAAAGACTACTATACTAA
CTCTTTCCATTATGATGTTCGTAAAAATCCAACGCCATTTGAAAAATTAGAGTTTGAAAAAGATTACCCTGTTTATGCTA
ATGGTGGATTTATTCACTACTGTGAATACCCAGTTCTTCAACAAAATCCGAAAGCACTTGAAGCCGTTTGGGACTTTGCT
TACGACCGTATTGGTTATCTTGGGACAAATGCGCCAATTGACCATTGTTACGCTTGTGGTTTTGAAGGAGATTTCACTCC
AACAGAACGTGGTTTCAAATGTCCACAATGTGGCAATGATGATCCTAAAACCTGTGACGTTGTAAAACGTACCTGTGGAT
ATCTTGGAAATCCTCAAGCACGTCCAATGGTTCATGGTCGTCACAAAGAAATTTCATCGCGTGTAAAACACATGAACGGT
TCTGTTGGAGCTTTGAATGATGGAAATTTGATTGATTCAGTCGAAGTTGACGAAGCAAAATCAAAATATTTTGCGGAGAA
ATAA

Upstream 100 bases:

>100_bases
CGACACAAGATATTGTGTGTCATTACATAATTTATTCTATATATTGTGTCATTTGCGAGAATTTGATAGAATAGATGATG
TAAATGAAGAGGATGGATAT

Downstream 100 bases:

>100_bases
GTATGAACAATCCAAAACCAGGAGAATGGAGAGCTGATGAGCTCTCACAAAATTATATTGCAGATTATAAGCCTTTTAAC
TTTGTTGATGGTGAGGGCGT

Product: anaerobic ribonucleoside triphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 747; Mature: 747

Protein sequence:

>747_residues
MKTEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDKSVLSELTDRVVSEIFSRFSENVKIYEIQSIVE
QELLESGETALAEEYISYRANRDLARTKATDINFTIEKLINRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPP
HVANAHQKGDIHYHDLDYSPFTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
DEVLAPYAKLNYQKHLKDAQKWIDGDEKREAYAREKTAKDIYDAMQSLEYEINTLFTSNGQTPFVTVGFGLGDDWYAREI
QKAILKVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPNYDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRS
FLQGWKDANGNDVTAGRNNLGVVTVNLPRIALEAAGNKEKFWEIFNERVEIAHDALAFRVERAKEAQPKNAPILFMNGAL
GRLDSEGSVDDLYNNERATVSLGYIGLYEVATTFYGPTWESNPEAKAFTIEIVKRMHEDCEDWSKASGYHYSVYSTPSES
LTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPFEKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFA
YDRIGYLGTNAPIDHCYACGFEGDFTPTERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
SVGALNDGNLIDSVEVDEAKSKYFAEK

Sequences:

>Translated_747_residues
MKTEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDKSVLSELTDRVVSEIFSRFSENVKIYEIQSIVE
QELLESGETALAEEYISYRANRDLARTKATDINFTIEKLINRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPP
HVANAHQKGDIHYHDLDYSPFTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
DEVLAPYAKLNYQKHLKDAQKWIDGDEKREAYAREKTAKDIYDAMQSLEYEINTLFTSNGQTPFVTVGFGLGDDWYAREI
QKAILKVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPNYDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRS
FLQGWKDANGNDVTAGRNNLGVVTVNLPRIALEAAGNKEKFWEIFNERVEIAHDALAFRVERAKEAQPKNAPILFMNGAL
GRLDSEGSVDDLYNNERATVSLGYIGLYEVATTFYGPTWESNPEAKAFTIEIVKRMHEDCEDWSKASGYHYSVYSTPSES
LTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPFEKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFA
YDRIGYLGTNAPIDHCYACGFEGDFTPTERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
SVGALNDGNLIDSVEVDEAKSKYFAEK
>Mature_747_residues
MKTEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDKSVLSELTDRVVSEIFSRFSENVKIYEIQSIVE
QELLESGETALAEEYISYRANRDLARTKATDINFTIEKLINRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPP
HVANAHQKGDIHYHDLDYSPFTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
DEVLAPYAKLNYQKHLKDAQKWIDGDEKREAYAREKTAKDIYDAMQSLEYEINTLFTSNGQTPFVTVGFGLGDDWYAREI
QKAILKVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPNYDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRS
FLQGWKDANGNDVTAGRNNLGVVTVNLPRIALEAAGNKEKFWEIFNERVEIAHDALAFRVERAKEAQPKNAPILFMNGAL
GRLDSEGSVDDLYNNERATVSLGYIGLYEVATTFYGPTWESNPEAKAFTIEIVKRMHEDCEDWSKASGYHYSVYSTPSES
LTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPFEKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFA
YDRIGYLGTNAPIDHCYACGFEGDFTPTERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
SVGALNDGNLIDSVEVDEAKSKYFAEK

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glycine radical domain [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=713, Percent_Identity=51.7531556802244, Blast_Score=756, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR001150
- InterPro:   IPR019777
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF01228 Gly_radical [H]

EC number: =1.17.4.2 [H]

Molecular weight: Translated: 84147; Mature: 84147

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS51161 ATP_CONE ; PS00850 GLY_RADICAL_1 ; PS51149 GLY_RADICAL_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDKSVLSELTDRVVS
CCCCCEECCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIFSRFSENVKIYEIQSIVEQELLESGETALAEEYISYRANRDLARTKATDINFTIEKLI
HHHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHC
NRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPPHVANAHQKGDIHYHDLDYSP
CCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCHHCCCCCCCCEEEEECCCCC
FTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
HHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DEVLAPYAKLNYQKHLKDAQKWIDGDEKREAYAREKTAKDIYDAMQSLEYEINTLFTSNG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
QTPFVTVGFGLGDDWYAREIQKAILKVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPN
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRSFLQGWKDANGNDVTAGRNNL
CCHHHHHHHHHHHHCCHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEECCCCCCE
GVVTVNLPRIALEAAGNKEKFWEIFNERVEIAHDALAFRVERAKEAQPKNAPILFMNGAL
EEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GRLDSEGSVDDLYNNERATVSLGYIGLYEVATTFYGPTWESNPEAKAFTIEIVKRMHEDC
CCCCCCCCHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EDWSKASGYHYSVYSTPSESLTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPF
HHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCH
EKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFAYDRIGYLGTNAPIDHCYACG
HHCCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHEEEC
FEGDFTPTERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SVGALNDGNLIDSVEVDEAKSKYFAEK
CCCCCCCCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKTEVKYQDVTLEEINVIKRDGRSVKFNSEKIFDALTKAAKKVELTDKSVLSELTDRVVS
CCCCCEECCCCHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIFSRFSENVKIYEIQSIVEQELLESGETALAEEYISYRANRDLARTKATDINFTIEKLI
HHHHHHHCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHC
NRDQTVVNENANKDSNVFNTQRDLTAGAVSKAIGLKLLPPHVANAHQKGDIHYHDLDYSP
CCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCEECCCHHCCCCCCCCEEEEECCCCC
FTTMANCCLIDFKNMFENGFKLGNAQVDSPKSIQTATAQASQIIANVASSQYGGCSFDRA
HHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
DEVLAPYAKLNYQKHLKDAQKWIDGDEKREAYAREKTAKDIYDAMQSLEYEINTLFTSNG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCC
QTPFVTVGFGLGDDWYAREIQKAILKVRIGGLGSEHRTAIFPKLIFTLKRGLNLEVGTPN
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YDIKELALECSTKRMYPDILSYDKIVELTGSFKASMGCRSFLQGWKDANGNDVTAGRNNL
CCHHHHHHHHHHHHCCHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEECCCCCCE
GVVTVNLPRIALEAAGNKEKFWEIFNERVEIAHDALAFRVERAKEAQPKNAPILFMNGAL
EEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCC
GRLDSEGSVDDLYNNERATVSLGYIGLYEVATTFYGPTWESNPEAKAFTIEIVKRMHEDC
CCCCCCCCHHHHCCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
EDWSKASGYHYSVYSTPSESLTDRFCRMDKEKFGSVADITDKDYYTNSFHYDVRKNPTPF
HHHHHCCCEEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCEEEECCCCCCCH
EKLEFEKDYPVYANGGFIHYCEYPVLQQNPKALEAVWDFAYDRIGYLGTNAPIDHCYACG
HHCCCCCCCCEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHEEEC
FEGDFTPTERGFKCPQCGNDDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMNG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCC
SVGALNDGNLIDSVEVDEAKSKYFAEK
CCCCCCCCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8421692; 7610040; 9278503; 8083158; 7852304 [H]