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The map label for this gene is luxS [H]

Identifier: 125623146

GI number: 125623146

Start: 261789

End: 262265

Strand: Reverse

Name: luxS [H]

Synonym: llmg_0273

Alternate gene names: 125623146

Gene position: 262265-261789 (Counterclockwise)

Preceding gene: 125623153

Following gene: 125623145

Centisome position: 10.37

GC content: 39.41

Gene sequence:

>477_bases
ATGGCTGAAGTAGAATCTTTTCAATTAGATCACACAAAAGTACTTGCCCCTTACGTACGCTTAATTGGTAGCGAAACTGG
ACCGAAAGGTGATGTTATTACTAACTTTGACGTTCGTTTTGTACAACCTAATGCCAATGCCATTGGTATGGCTGCTTTAC
ATACTATCGAGCATAGTATGGCAAGTTTGATTCGCGATAGAATCGATGGTATGATTGACTTTTCACCATTTGGTTGTCAA
ACTGGTTTCCACATGATTATGTGGGGTGAACATAGTTCCGAAGAAATTGCGAAAGTGATTAAATCTTCTCTAGAAGAGCT
TTCAAGTGATGAATTTGGTTGGGACAATGTTCCTGGTGTTGCGGAAAAAGAATGCGGAAACTACCGTAATCACTCACTTT
TCGGTGCTAAAGAATGGTCTAAGAAAATCCTCGCTGAAGGAATTTCAACTGACCCTTACGAACGTAAAGTCATTTAA

Upstream 100 bases:

>100_bases
TTCGCTTAAAAAATGATAGAATAGAATTAGAATTTAAAATAAAGGAGGAGATACTGACAAGGCTGACTTTTATCGGCTGA
GTTTTGTATCATATATTTTT

Downstream 100 bases:

>100_bases
AATTCGCTCACTTACCGCACGAAGTAATTTTAAACTATCAACGTTTTTAGATTACAACACTTAATCATTTCCTTTTGTAA
GGAATTTAATAGGTTAATTT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSMASLIRDRIDGMIDFSPFGCQ
TGFHMIMWGEHSSEEIAKVIKSSLEELSSDEFGWDNVPGVAEKECGNYRNHSLFGAKEWSKKILAEGISTDPYERKVI

Sequences:

>Translated_158_residues
MAEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSMASLIRDRIDGMIDFSPFGCQ
TGFHMIMWGEHSSEEIAKVIKSSLEELSSDEFGWDNVPGVAEKECGNYRNHSLFGAKEWSKKILAEGISTDPYERKVI
>Mature_157_residues
AEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSMASLIRDRIDGMIDFSPFGCQT
GFHMIMWGEHSSEEIAKVIKSSLEELSSDEFGWDNVPGVAEKECGNYRNHSLFGAKEWSKKILAEGISTDPYERKVI

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=158, Percent_Identity=33.5443037974684, Blast_Score=107, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 17605; Mature: 17474

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSM
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHH
ASLIRDRIDGMIDFSPFGCQTGFHMIMWGEHSSEEIAKVIKSSLEELSSDEFGWDNVPGV
HHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AEKECGNYRNHSLFGAKEWSKKILAEGISTDPYERKVI
CHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AEVESFQLDHTKVLAPYVRLIGSETGPKGDVITNFDVRFVQPNANAIGMAALHTIEHSM
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEECCEEEEECCCCCCHHHHHHHHHHHHH
ASLIRDRIDGMIDFSPFGCQTGFHMIMWGEHSSEEIAKVIKSSLEELSSDEFGWDNVPGV
HHHHHHHHCCEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AEKECGNYRNHSLFGAKEWSKKILAEGISTDPYERKVI
CHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]