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The map label for this gene is dhaM [H]

Identifier: 125623132

GI number: 125623132

Start: 244314

End: 244892

Strand: Direct

Name: dhaM [H]

Synonym: llmg_0257

Alternate gene names: 125623132

Gene position: 244314-244892 (Clockwise)

Preceding gene: 125623131

Following gene: 125623133

Centisome position: 9.66

GC content: 38.17

Gene sequence:

>579_bases
ATGTTAACAGTCAATACAACCATTGAATGGTTAGGAAAATTCAACGAAAAAATACAAGAAAATAAAGCTTATCTAAGCGA
ACTAGACGGACCGATTGGTGACGGGGACCATGGTGCAAATATGGCTCGTGGGATGTCTGAAACAATGAAAGCATTGGAAG
GTTCAAACTTTGAAAATGTTTCAGAAATCTTTAAAAAAGTGGCCATGACCCTAATGTCAAAAGTAGGCGGAGCTTCTGGA
CCTTTGTATGGTTCAGCCTTTCTAGCCATGAGTAAGGCTGCCACAGAAACTTTGGATACAAGTGAATTAATTTATGCTGG
ATTAGAAGCTATTCAAAAAAGAGGAAAAGCTCAAGTCGGTGAAAAAACGATGGTTGATATCTGGTCAGCATTTTTAAAAG
ACCTGCAAACAGATTCAGCTTCCAAAGAAAATTTAGAAAAAGTTGTTAAAGCAAGTGCAGGACTTTTAGCTACCAAAGGA
CGAGCTTCTTATTTGGGAGAACGTTCAATTGGGCACATTGATCCAGGAACACAATCAAGTGCTTATTTATTTGAAACACT
TTTGGAGGTAGTAGCATGA

Upstream 100 bases:

>100_bases
GGCAGGCTTGTCACTTACAATGATTAAGTTGGAAGATGACCAATGGCTCAAAAATCTTAATGAAGAAGTAAAAACCATTT
CTTGGGGATAAGGAGAGAAG

Downstream 100 bases:

>100_bases
CTTATGGAATTGTAATCGTTTCTCATTCTTCTGAGATTGCCTCAGGATTAAAAAAATTAATTCGTGAAGTTGCTAAAGAT
ATTTCACTAACCGCTATAGG

Product: dihydroxyacetone kinase DhaM

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MLTVNTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEGSNFENVSEIFKKVAMTLMSKVGGASG
PLYGSAFLAMSKAATETLDTSELIYAGLEAIQKRGKAQVGEKTMVDIWSAFLKDLQTDSASKENLEKVVKASAGLLATKG
RASYLGERSIGHIDPGTQSSAYLFETLLEVVA

Sequences:

>Translated_192_residues
MLTVNTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEGSNFENVSEIFKKVAMTLMSKVGGASG
PLYGSAFLAMSKAATETLDTSELIYAGLEAIQKRGKAQVGEKTMVDIWSAFLKDLQTDSASKENLEKVVKASAGLLATKG
RASYLGERSIGHIDPGTQSSAYLFETLLEVVA
>Mature_192_residues
MLTVNTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEGSNFENVSEIFKKVAMTLMSKVGGASG
PLYGSAFLAMSKAATETLDTSELIYAGLEAIQKRGKAQVGEKTMVDIWSAFLKDLQTDSASKENLEKVVKASAGLLATKG
RASYLGERSIGHIDPGTQSSAYLFETLLEVVA

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=171, Percent_Identity=36.2573099415205, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787449, Length=204, Percent_Identity=37.2549019607843, Blast_Score=130, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17565018, Length=186, Percent_Identity=31.1827956989247, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323570, Length=186, Percent_Identity=29.5698924731183, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 20580; Mature: 20580

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVNTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEGSNFENV
CEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
SEIFKKVAMTLMSKVGGASGPLYGSAFLAMSKAATETLDTSELIYAGLEAIQKRGKAQVG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHCC
EKTMVDIWSAFLKDLQTDSASKENLEKVVKASAGLLATKGRASYLGERSIGHIDPGTQSS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHCCCHHHHHCCCCCCCCCCCCCCH
AYLFETLLEVVA
HHHHHHHHHHHC
>Mature Secondary Structure
MLTVNTTIEWLGKFNEKIQENKAYLSELDGPIGDGDHGANMARGMSETMKALEGSNFENV
CEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHH
SEIFKKVAMTLMSKVGGASGPLYGSAFLAMSKAATETLDTSELIYAGLEAIQKRGKAQVG
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHCC
EKTMVDIWSAFLKDLQTDSASKENLEKVVKASAGLLATKGRASYLGERSIGHIDPGTQSS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHCCCHHHHHCCCCCCCCCCCCCCH
AYLFETLLEVVA
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]