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The map label for this gene is msrB [H]

Identifier: 125623078

GI number: 125623078

Start: 191414

End: 191842

Strand: Direct

Name: msrB [H]

Synonym: llmg_0201

Alternate gene names: 125623078

Gene position: 191414-191842 (Clockwise)

Preceding gene: 125623074

Following gene: 125623082

Centisome position: 7.57

GC content: 36.83

Gene sequence:

>429_bases
ATGAAAAAAGAAGAACTTAAAAAGAAATTGAGTCCACTTGCTTATCGTGTTACTCAAGAAAATGGGACAGAAGCTCGCTT
CACTAATGAGTTTGATGATTTCTTTGAAAAAGGCTTGTATGTTGATATTGTCAGTGGAGAACCACTGTTTACAAGTCTTG
ATAAATATCAATCTGGGTGTGGCTGGCCAGCCTTTACACAACCAATTGACAAAAAAGTGGTCAAAGAAAAACGAGATAAG
TCTCTTTTTATGGAGCGTACAGAAGTTCGTTCTAGTAATGCTGACAGCCACTTGGGTCACGTTTTTACTGATGGACCTTT
AGATAAAGGGGGCTTACGTTACTGTATCAATTCTGCAGCTTTGCGTTTTATCCCCTTTGACCAATTAGAATCAGAAGGAT
ACGGAGATTATATAAAATATTTTTCATAA

Upstream 100 bases:

>100_bases
TTGCGCTGAAAACTCAGCAGTGTAAACTATTTGTCAACTTAGTTTACACCAATGTCAAAAGGGTTGACAATCAATAATCA
CTTACAAGAAAGGAAAGTTA

Downstream 100 bases:

>100_bases
TTCCGCTGATTAAATAAAAAAGTTACTGACAGAAACTCAAAACAATGAAAAGTATTTTGTCAGTAACTTTTTATAAGCAA
AAGAAAAATTCTGATGTTTG

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MKKEELKKKLSPLAYRVTQENGTEARFTNEFDDFFEKGLYVDIVSGEPLFTSLDKYQSGCGWPAFTQPIDKKVVKEKRDK
SLFMERTEVRSSNADSHLGHVFTDGPLDKGGLRYCINSAALRFIPFDQLESEGYGDYIKYFS

Sequences:

>Translated_142_residues
MKKEELKKKLSPLAYRVTQENGTEARFTNEFDDFFEKGLYVDIVSGEPLFTSLDKYQSGCGWPAFTQPIDKKVVKEKRDK
SLFMERTEVRSSNADSHLGHVFTDGPLDKGGLRYCINSAALRFIPFDQLESEGYGDYIKYFS
>Mature_142_residues
MKKEELKKKLSPLAYRVTQENGTEARFTNEFDDFFEKGLYVDIVSGEPLFTSLDKYQSGCGWPAFTQPIDKKVVKEKRDK
SLFMERTEVRSSNADSHLGHVFTDGPLDKGGLRYCINSAALRFIPFDQLESEGYGDYIKYFS

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=47.2, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=47.2, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=47.2, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=47.2, Blast_Score=119, Evalue=6e-28,
Organism=Homo sapiens, GI117606353, Length=132, Percent_Identity=41.6666666666667, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1788077, Length=120, Percent_Identity=48.3333333333333, Blast_Score=120, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=125, Percent_Identity=48, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17553450, Length=125, Percent_Identity=48, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=122, Percent_Identity=32.7868852459016, Blast_Score=71, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221378664, Length=125, Percent_Identity=52, Blast_Score=128, Evalue=9e-31,
Organism=Drosophila melanogaster, GI221378662, Length=132, Percent_Identity=50, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45553335, Length=132, Percent_Identity=49.2424242424242, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356369, Length=132, Percent_Identity=49.2424242424242, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24645799, Length=132, Percent_Identity=49.2424242424242, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24645804, Length=143, Percent_Identity=46.1538461538462, Blast_Score=122, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24645801, Length=143, Percent_Identity=46.1538461538462, Blast_Score=122, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16300; Mature: 16300

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEELKKKLSPLAYRVTQENGTEARFTNEFDDFFEKGLYVDIVSGEPLFTSLDKYQSGC
CCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHCCC
GWPAFTQPIDKKVVKEKRDKSLFMERTEVRSSNADSHLGHVFTDGPLDKGGLRYCINSAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHH
LRFIPFDQLESEGYGDYIKYFS
HEECCHHHHCCCCCCCHHHHCC
>Mature Secondary Structure
MKKEELKKKLSPLAYRVTQENGTEARFTNEFDDFFEKGLYVDIVSGEPLFTSLDKYQSGC
CCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHCCC
GWPAFTQPIDKKVVKEKRDKSLFMERTEVRSSNADSHLGHVFTDGPLDKGGLRYCINSAA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCHHHHHHHHHH
LRFIPFDQLESEGYGDYIKYFS
HEECCHHHHCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]