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The map label for this gene is hepT [H]

Identifier: 125623073

GI number: 125623073

Start: 184725

End: 185705

Strand: Direct

Name: hepT [H]

Synonym: llmg_0196

Alternate gene names: 125623073

Gene position: 184725-185705 (Clockwise)

Preceding gene: 125623072

Following gene: 125623074

Centisome position: 7.3

GC content: 38.02

Gene sequence:

>981_bases
TTGCTCACATTTTGGCAGGATTATCCCGAAATTCAGAATAAATTAAAGGATGTTCAAGCGCTCATGATTGAGCGTTTAAA
AATTAATAATCAAGAAATAGAAGTAGCACTGCAAAAATTTGCATCACGTGGCGGGAAAATGGTGCGTCCTGCGCTTTTTT
TGCTGTTCGCTGGTATTGTTCCTAATGGCTCAAAAGATGAGGAGAAACTAATCAAAATTGCTGCTTCCTTAGAAATGCTT
CACTCAGCAACATTGATTCATGATGATATTATTGATGACTCACCTCTACGTCGTGGAATGCCATCAGTAGAATCGCAATT
TGGTAAAGATGTGGCAGTTTATGCTGGTGATTTTGTTTATACCGTTTATTTTGAGTTACTGATTGAAACGATGAATGGGA
CGAGTTTTGTTGCTAAAAATGCTCAGTCAATGAAAAGAATTCTTCAAGGGGAGTTAACTCAAATGCAGTCTGCATTTGAT
AAAAACAATACGGCTCGCCGCTACATGAAAGCTATCAGTGGGAAAACTGCTGAATTACTCAGTTTAAGTTGCCTAGAAGG
TGTTTATTTTGCAGGTGGTGACAAGAAACTACAGCATTCGGCACGGAAAATTGGTCGAGCGATTGGTCTAGCTTTTCAAG
TTTACGATGATATTTTAAATTTCACTGTAGGGCTTGATGAAGCCGATAAACCAATTTTAACTGATTTTCGTCAAGGAATT
TACACCTTACCCTTGCTTTTGGCTAGAGAAGTTAATGAAGCAGCAATCGCTCCATATCTAGAAGCACCAGAAAAGCTATC
GAGACAAGAATGTTTAGATTTAGCAGAATTGGTGACAGAATTAGGTGGAATAACGGGTTCACTTCTTGTTGCAGGAAGGC
TGACAGAACTTGCCTTGAACGAAATTAAAAAATTACCAGAATCACCTAACCGTCAAATTTTAGAAGAAGCGACACAGATT
TTATTAGAGCGAAATTATTAA

Upstream 100 bases:

>100_bases
TGTTCGCAACATTTGGTCTATTTTGCTAAAATAGAGTAAAGTATTTGATAAATAATTATCAAAAGAAATGAATGAATTAT
CGAGAGGAAAGAGAAAAACA

Downstream 100 bases:

>100_bases
AAGCCTGTCACCGATAGGTTTTTTAATTATTATAAGTGTCGTCAACTGACGAAGCTTGAATAAAAATATCTAGTTTTTTT
GTAGAAAGTTTTATATTAAA

Product: prenyl transferase

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLTFWQDYPEIQNKLKDVQALMIERLKINNQEIEVALQKFASRGGKMVRPALFLLFAGIVPNGSKDEEKLIKIAASLEML
HSATLIHDDIIDDSPLRRGMPSVESQFGKDVAVYAGDFVYTVYFELLIETMNGTSFVAKNAQSMKRILQGELTQMQSAFD
KNNTARRYMKAISGKTAELLSLSCLEGVYFAGGDKKLQHSARKIGRAIGLAFQVYDDILNFTVGLDEADKPILTDFRQGI
YTLPLLLAREVNEAAIAPYLEAPEKLSRQECLDLAELVTELGGITGSLLVAGRLTELALNEIKKLPESPNRQILEEATQI
LLERNY

Sequences:

>Translated_326_residues
MLTFWQDYPEIQNKLKDVQALMIERLKINNQEIEVALQKFASRGGKMVRPALFLLFAGIVPNGSKDEEKLIKIAASLEML
HSATLIHDDIIDDSPLRRGMPSVESQFGKDVAVYAGDFVYTVYFELLIETMNGTSFVAKNAQSMKRILQGELTQMQSAFD
KNNTARRYMKAISGKTAELLSLSCLEGVYFAGGDKKLQHSARKIGRAIGLAFQVYDDILNFTVGLDEADKPILTDFRQGI
YTLPLLLAREVNEAAIAPYLEAPEKLSRQECLDLAELVTELGGITGSLLVAGRLTELALNEIKKLPESPNRQILEEATQI
LLERNY
>Mature_326_residues
MLTFWQDYPEIQNKLKDVQALMIERLKINNQEIEVALQKFASRGGKMVRPALFLLFAGIVPNGSKDEEKLIKIAASLEML
HSATLIHDDIIDDSPLRRGMPSVESQFGKDVAVYAGDFVYTVYFELLIETMNGTSFVAKNAQSMKRILQGELTQMQSAFD
KNNTARRYMKAISGKTAELLSLSCLEGVYFAGGDKKLQHSARKIGRAIGLAFQVYDDILNFTVGLDEADKPILTDFRQGI
YTLPLLLAREVNEAAIAPYLEAPEKLSRQECLDLAELVTELGGITGSLLVAGRLTELALNEIKKLPESPNRQILEEATQI
LLERNY

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=329, Percent_Identity=28.8753799392097, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1789578, Length=313, Percent_Identity=28.1150159744409, Blast_Score=124, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17505681, Length=235, Percent_Identity=33.1914893617021, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319475, Length=314, Percent_Identity=26.7515923566879, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24651612, Length=289, Percent_Identity=29.0657439446367, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36392; Mature: 36392

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFWQDYPEIQNKLKDVQALMIERLKINNQEIEVALQKFASRGGKMVRPALFLLFAGIV
CCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PNGSKDEEKLIKIAASLEMLHSATLIHDDIIDDSPLRRGMPSVESQFGKDVAVYAGDFVY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHCCCEEHHHHHHHH
TVYFELLIETMNGTSFVAKNAQSMKRILQGELTQMQSAFDKNNTARRYMKAISGKTAELL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
SLSCLEGVYFAGGDKKLQHSARKIGRAIGLAFQVYDDILNFTVGLDEADKPILTDFRQGI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YTLPLLLAREVNEAAIAPYLEAPEKLSRQECLDLAELVTELGGITGSLLVAGRLTELALN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EIKKLPESPNRQILEEATQILLERNY
HHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTFWQDYPEIQNKLKDVQALMIERLKINNQEIEVALQKFASRGGKMVRPALFLLFAGIV
CCCCHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PNGSKDEEKLIKIAASLEMLHSATLIHDDIIDDSPLRRGMPSVESQFGKDVAVYAGDFVY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHCCCEEHHHHHHHH
TVYFELLIETMNGTSFVAKNAQSMKRILQGELTQMQSAFDKNNTARRYMKAISGKTAELL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHH
SLSCLEGVYFAGGDKKLQHSARKIGRAIGLAFQVYDDILNFTVGLDEADKPILTDFRQGI
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YTLPLLLAREVNEAAIAPYLEAPEKLSRQECLDLAELVTELGGITGSLLVAGRLTELALN
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EIKKLPESPNRQILEEATQILLERNY
HHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]