Click here to switch to the map view.

The map label for this gene is bglS [H]

Identifier: 125623067

GI number: 125623067

Start: 178257

End: 179693

Strand: Direct

Name: bglS [H]

Synonym: llmg_0190

Alternate gene names: 125623067

Gene position: 178257-179693 (Clockwise)

Preceding gene: 125623066

Following gene: 125623068

Centisome position: 7.05

GC content: 39.67

Gene sequence:

>1437_bases
ATGGAACACAAAAAATTGAGCTCATTTCCAAGTGATTTTCTTTGGGGTTCAGCTTCAGCAGCTTATCAAGTTGAAGGAGC
ACCTTTTGAAGATGGTAAAAAAGCGAGTGTCTGGGATAACTTTGTCCGCATTCCGGGTAAAACTTTTAAAGGGACAAACG
GGGATGTTGCTGTTGATCATTACCATCGTTACAAAGAAGATGTCGCTTTGATGAAAGAATTAGGACTTAAATCCTACCGT
TTTTCGATTGCTTGGACACGTATTTTACCTGACGGACGTGGCGAAGTCAATCAAGCGGGCTTGAAATTCTATGAAGACTT
GATTGATGAGTTGATTGCTAATCATATTGAACCAATTGTCACGATTTATCATTGGGACTTGCCCCAAGCTTTAGAAGACC
TGTATGGCGGCTGGGAATCACGAGAAATTATCTCAGATTTTGTTAACTATGCTGAAGTTTTGTTTAAAGCCTTTAAAGGT
AAAGTAAAATATTGGGTATCGCTTAATGAACAAAATATCTTTACAAGTCAAGGTTGGTCACTCGCGACTCACCCACCAGG
GAAAAGAGATATGAAGCTCTTTTATCAGGTCAATCATATCGCGAATTTGGCAAATGCTGCGGTAATTAATAAGTTTCATG
AGCTTGAAATGGATGGACAAATTGGCCCTTCATTCGCCTATACACCGCAGTATGCTAAGGATTCTGACCCTTTAAATGTT
TTGGCTGCTGAGAACGCTGAAGAACTTTATAGCCACTTTTGGATGGATGTTTACCTTTATGGTGAATACCCAATTGCGGC
AATGGCTTATCTGCGGGAAAATGGTTTAGCACCTGAATTTGAAGCAGGAGATGCTGAACTCTTGAAGTCGGCCAAACCTG
ATTTTCTAGGCATTAATTACTACCAAACGGCGACTAACGCTTGGAATCCAATTGATGGTGGGGTTGGAGTTGGTTCATTT
AATACAAGCGGTAAAAAAGGAACAACCAAAGAATCAGGAATTCCTGGGCTTCATAAAAAAATTCAAAATCCATTCATTGA
CCGCACAAATTGGGATTGGGAAATTGACCCAGAAGGTTTGCGAATTGCACTCCGTCGAATTACTTCACGCTATCGTATTC
CGGTCATGATTACGGAAAATGGTTTGGGTGAATATGACAAAGTTGAAGAGGGCAAAATTCATGATGATTACCGAATTAAA
TACCTAGAAAGTCATGTTAAGGCAATCAAAGAAGCCATGACTGACGGTGCTACGGTCATTGGTTATCACACTTGGTCTTA
TACTGACTTACTTTCATGGTTGAACGGTTATCAAAAACGTTATGGTTTTGTTTATGTTGACCAAGACGAAACAATGGAAG
GTTCCTTAAAACGAATTCCTAAGGATTCTTATTACTGGTATCAACATCTTATTGAAACAAATGGCGAAGAGCTCTAA

Upstream 100 bases:

>100_bases
TTTTTTGTCTAAAATTAAAAAACAAATTCCAAAATATAAAACAAAATAAAACGGTTACAAATGTTATAATAGTAGTATAA
ATAACCAGTGGGGGAATAAT

Downstream 100 bases:

>100_bases
ACAAAGAGCACTCAAGTGAGTGCTCTTTTTATGTTATAATAATAAAAAAACAAAAGAGGTGAAGAATGAAAATTCGTGGA
TTTGAAGTAGTAGCTAAATA

Product: Beta-glucosidase A

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MEHKKLSSFPSDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDHYHRYKEDVALMKELGLKSYR
FSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANHIEPIVTIYHWDLPQALEDLYGGWESREIISDFVNYAEVLFKAFKG
KVKYWVSLNEQNIFTSQGWSLATHPPGKRDMKLFYQVNHIANLANAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINYYQTATNAWNPIDGGVGVGSF
NTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGLRIALRRITSRYRIPVMITENGLGEYDKVEEGKIHDDYRIK
YLESHVKAIKEAMTDGATVIGYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNGEEL

Sequences:

>Translated_478_residues
MEHKKLSSFPSDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDHYHRYKEDVALMKELGLKSYR
FSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANHIEPIVTIYHWDLPQALEDLYGGWESREIISDFVNYAEVLFKAFKG
KVKYWVSLNEQNIFTSQGWSLATHPPGKRDMKLFYQVNHIANLANAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINYYQTATNAWNPIDGGVGVGSF
NTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGLRIALRRITSRYRIPVMITENGLGEYDKVEEGKIHDDYRIK
YLESHVKAIKEAMTDGATVIGYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNGEEL
>Mature_478_residues
MEHKKLSSFPSDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDHYHRYKEDVALMKELGLKSYR
FSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANHIEPIVTIYHWDLPQALEDLYGGWESREIISDFVNYAEVLFKAFKG
KVKYWVSLNEQNIFTSQGWSLATHPPGKRDMKLFYQVNHIANLANAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINYYQTATNAWNPIDGGVGVGSF
NTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGLRIALRRITSRYRIPVMITENGLGEYDKVEEGKIHDDYRIK
YLESHVKAIKEAMTDGATVIGYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNGEEL

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=484, Percent_Identity=34.297520661157, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI110681710, Length=486, Percent_Identity=32.0987654320988, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI13273313, Length=488, Percent_Identity=32.5819672131148, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI24497614, Length=498, Percent_Identity=30.7228915662651, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI28376633, Length=480, Percent_Identity=30, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=46.9387755102041, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI2367174, Length=504, Percent_Identity=37.6984126984127, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789070, Length=496, Percent_Identity=36.6935483870968, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI2367270, Length=490, Percent_Identity=37.7551020408163, Blast_Score=291, Evalue=8e-80,
Organism=Caenorhabditis elegans, GI17552856, Length=490, Percent_Identity=30.8163265306122, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17539390, Length=488, Percent_Identity=30.327868852459, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356577, Length=493, Percent_Identity=31.8458417849899, Blast_Score=216, Evalue=4e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54678; Mature: 54678

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHKKLSSFPSDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDH
CCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEHHH
YHRYKEDVALMKELGLKSYRFSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANHIEPIV
HHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
TIYHWDLPQALEDLYGGWESREIISDFVNYAEVLFKAFKGKVKYWVSLNEQNIFTSQGWS
EEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCE
LATHPPGKRDMKLFYQVNHIANLANAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINY
EECCCHHHHHHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECEE
YQTATNAWNPIDGGVGVGSFNTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGL
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEECCHHH
RIALRRITSRYRIPVMITENGLGEYDKVEEGKIHDDYRIKYLESHVKAIKEAMTDGATVI
HHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNGEEL
EEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEHKKLSSFPSDFLWGSASAAYQVEGAPFEDGKKASVWDNFVRIPGKTFKGTNGDVAVDH
CCCCCCCCCCCHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEHHH
YHRYKEDVALMKELGLKSYRFSIAWTRILPDGRGEVNQAGLKFYEDLIDELIANHIEPIV
HHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
TIYHWDLPQALEDLYGGWESREIISDFVNYAEVLFKAFKGKVKYWVSLNEQNIFTSQGWS
EEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEECCCCE
LATHPPGKRDMKLFYQVNHIANLANAAVINKFHELEMDGQIGPSFAYTPQYAKDSDPLNV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEE
LAAENAEELYSHFWMDVYLYGEYPIAAMAYLRENGLAPEFEAGDAELLKSAKPDFLGINY
EECCCHHHHHHHHEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEECEE
YQTATNAWNPIDGGVGVGSFNTSGKKGTTKESGIPGLHKKIQNPFIDRTNWDWEIDPEGL
EECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEECCHHH
RIALRRITSRYRIPVMITENGLGEYDKVEEGKIHDDYRIKYLESHVKAIKEAMTDGATVI
HHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEE
GYHTWSYTDLLSWLNGYQKRYGFVYVDQDETMEGSLKRIPKDSYYWYQHLIETNGEEL
EEECCCHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]