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The map label for this gene is yyaH [H]

Identifier: 125623061

GI number: 125623061

Start: 173038

End: 173418

Strand: Direct

Name: yyaH [H]

Synonym: llmg_0184

Alternate gene names: 125623061

Gene position: 173038-173418 (Clockwise)

Preceding gene: 125623060

Following gene: 125623062

Centisome position: 6.84

GC content: 35.7

Gene sequence:

>381_bases
ATGAAAATTGAACATGTTGGCCTAATGGTTCAAGATTTGGAAGGAATGCGTCACTTTTATGAGCATTATTTTGAAGGACA
GGCAGGTCAAAAATATCATAATCCTAAAACGAATTTTCAATCTTACTTTTTAACTTTTTCTGATGGAGCGCGACTTGAAA
TTGGGACTAAAGAGAACTTGAAAAGTGATGACAAATCTGTTTGGACAGGTTATGCTCATTTAGCTATTTCTGTTGGTTCC
AAAGAAAAAGTGGATGAACTCTGTCAGCGATTTTTGGAAGATGGTTTTGAAGTCAAATCTGGGCCAAGAACGACTGGAGA
TGGATATTATGAAGCCGTAATCTTAGACCCTGAAGAAAATGAAATCGAAATTACTATTTGA

Upstream 100 bases:

>100_bases
TTGGTCGTTTCAAGAAACGTCAAATGGTTGCCATATTGGATAATGTTAATCGTGCCTACAACGGAGGTAGAGCGCACTAA
TCAAAGAAGAGAGAAATGTG

Downstream 100 bases:

>100_bases
AATAGCATCCTTTTGTAGGCTGTTATTTTTATTTTTCGAGAATAATTTTAGAAAGTAAACGCTAACAAAAATGTTTTCTT
ATTTCTACAGTTTTGTGTTA

Product: putative lactoylglutathione lyase

Products: glutathione; methylglyoxal

Alternate protein names: ORFF [H]

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MKIEHVGLMVQDLEGMRHFYEHYFEGQAGQKYHNPKTNFQSYFLTFSDGARLEIGTKENLKSDDKSVWTGYAHLAISVGS
KEKVDELCQRFLEDGFEVKSGPRTTGDGYYEAVILDPEENEIEITI

Sequences:

>Translated_126_residues
MKIEHVGLMVQDLEGMRHFYEHYFEGQAGQKYHNPKTNFQSYFLTFSDGARLEIGTKENLKSDDKSVWTGYAHLAISVGS
KEKVDELCQRFLEDGFEVKSGPRTTGDGYYEAVILDPEENEIEITI
>Mature_126_residues
MKIEHVGLMVQDLEGMRHFYEHYFEGQAGQKYHNPKTNFQSYFLTFSDGARLEIGTKENLKSDDKSVWTGYAHLAISVGS
KEKVDELCQRFLEDGFEVKSGPRTTGDGYYEAVILDPEENEIEITI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 14445; Mature: 14445

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEHVGLMVQDLEGMRHFYEHYFEGQAGQKYHNPKTNFQSYFLTFSDGARLEIGTKENL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCC
KSDDKSVWTGYAHLAISVGSKEKVDELCQRFLEDGFEVKSGPRTTGDGYYEAVILDPEEN
CCCCCHHEEEEEEEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCCC
EIEITI
EEEEEC
>Mature Secondary Structure
MKIEHVGLMVQDLEGMRHFYEHYFEGQAGQKYHNPKTNFQSYFLTFSDGARLEIGTKENL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCC
KSDDKSVWTGYAHLAISVGSKEKVDELCQRFLEDGFEVKSGPRTTGDGYYEAVILDPEEN
CCCCCHHEEEEEEEEEECCCHHHHHHHHHHHHHCCCEECCCCCCCCCCEEEEEEECCCCC
EIEITI
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]