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The map label for this gene is codY [H]

Identifier: 125623050

GI number: 125623050

Start: 163457

End: 164245

Strand: Direct

Name: codY [H]

Synonym: llmg_0172

Alternate gene names: 125623050

Gene position: 163457-164245 (Clockwise)

Preceding gene: 125623049

Following gene: 125623051

Centisome position: 6.46

GC content: 38.78

Gene sequence:

>789_bases
GTGGCTACATTACTTGAAAAAACACGTAAAATCACCGCGATTTTGCAAGATGGAGTGACCGATTTGCAACAAGAGTTGCC
ATACAACAGTATGACTGAACGCTTGGCAAACGTCATTGATTGCAACGCCTGCGTGATTAATACGAAGGGCGAGTTGCTTG
GTTACTCATTGCCTTACAATACAAACAATGATCGCGTTGACCAATTTTTCTACGATCGTAAATTGCCTGACGAATACGTT
CGTGCAGCAGTACGTATTTACGATACAATGGCAAACGTTCCTGTTGATCGTCCTTTAGCAATTTTCCCAGAAGAAAGTCT
TAGCGATTTTCCAAAAGGTGTAACAACTTTAGCGCCTATCTATGGTTCTGGAATGCGTCTTGGAACATTTATTATGTGGC
GTGAAGATGGTGAATTTACAGATGACGATCTTGTTTTGGTTGAGCTTGCAACAACAGTAATCGGTGTACAACTCTCAAAC
CTTAAACTTGAACAAATGGAAGAAAATATCCGTAAAGACACTATGGCAACAATGGCTGTTAATACACTTTCTTACTCAGA
AATGAAAGCTGTCAAAGCAATTATTGAAGAACTTGATGGTGAAGAAGGGCATGTTATTGCCTCTGTCATTGCTGACAAGA
TTGGTATTACACGTTCAGTGATTGTTAATGCTTTACGTAAACTTGAATCTGCTGGTGTTATTGAATCACGTTCACTTGGT
ATGAAAGGAACTTATCTTAAAGTTCTTAATACTGGTTTGTTTGATAAACTTGCTGGACGTAATTTCTAA

Upstream 100 bases:

>100_bases
ATTTTCTGACAATTTTTATTGTTTTTCATGCTTTTTTATGTTATACTGATTATGAAAAATTTTGTATAAAAACAAGAATA
TAAAAAAATAGGAGAACAAA

Downstream 100 bases:

>100_bases
AAGTCAGAGCTTAACGCTTGTTCTTTTATCATTTGTTTTTGCAGGTAGATAAATGGACAGCTAGATTGCGTTTAGCTTTC
GACTTCACAAGAACCTCCTA

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYV
RAAVRIYDTMANVPVDRPLAIFPEESLSDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSN
LKLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
MKGTYLKVLNTGLFDKLAGRNF

Sequences:

>Translated_262_residues
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYV
RAAVRIYDTMANVPVDRPLAIFPEESLSDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSN
LKLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
MKGTYLKVLNTGLFDKLAGRNF
>Mature_261_residues
ATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYVR
AAVRIYDTMANVPVDRPLAIFPEESLSDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNL
KLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLGM
KGTYLKVLNTGLFDKLAGRNF

Specific function: DNA-binding protein that represses the expression of many genes essential for supplying Lactococcus lactis with amino acids during growth in milk. Seem to act on the major components of the proteolytic system, including the cell wall proteinase (PrtP), th

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991 [H]

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY [H]

EC number: NA

Molecular weight: Translated: 29159; Mature: 29028

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCC
TNNDRVDQFFYDRKLPDEYVRAAVRIYDTMANVPVDRPLAIFPEESLSDFPKGVTTLAPI
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCHHHHHHH
YGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNLKLEQMEENIRKDTMATMAV
HCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCC
MKGTYLKVLNTGLFDKLAGRNF
CCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYN
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCC
TNNDRVDQFFYDRKLPDEYVRAAVRIYDTMANVPVDRPLAIFPEESLSDFPKGVTTLAPI
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHCCCCHHHHHHH
YGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNLKLEQMEENIRKDTMATMAV
HCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCC
MKGTYLKVLNTGLFDKLAGRNF
CCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471; 11401725 [H]