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The map label for this gene is cbr [H]

Identifier: 125623033

GI number: 125623033

Start: 145859

End: 146644

Strand: Reverse

Name: cbr [H]

Synonym: llmg_0154

Alternate gene names: 125623033

Gene position: 146644-145859 (Counterclockwise)

Preceding gene: 125623034

Following gene: 125623032

Centisome position: 5.8

GC content: 36.13

Gene sequence:

>786_bases
ATGAAAACACTCATCACAGGTGCAAATAAAGGAATTGGTTTTGCTCTTGCGCAAAATCTCGGTCATCGTGGCTATGAAGT
TTTAGTCGGAGCTCGTAATGAGACTCGTGGACAAGAAGCCGTTGAAAAATTGAAAGCCGAAGGAATCAATGCGGAATTTG
TCAAAGTTGATTTAGATGACTTAAATCAATTAACTAGCCTGTCAGCACTGACAGACATTGACTTACTCATTAATAATGCT
GGAATTTCTGGTAATATTCATTCAGATAAAGGACATCTTGATATGGAAAAATCAGCTTTTGATTATTCTAATTCTGACTT
AGAAGAAACAATCAAGACCAACTTTTTGGGAACACATGCAGTGATTACAGAACTCCTCCCACATTCACTGACCGAAAATG
CTAAAATTATTAACATCACCGTACCCGTTTCTCAGGAATATTGGATGCCGCTGGCCTATGTCACTTCAAAAGCCGCTCAG
AATGCCATGACTTTTGCTTTTGGTCATCAATTTAAAAAAGACAAATCACAAAAACAAATTTTTGCTGTCATGCCTGGGGC
TGTTGCAACAGATTTAAATGGCGCAAAAGTTGGTGACAGTCCTTTTGTCAAATCTCCAGAAGAAACAGCTCAAATGATTA
GTAAATTCATTTTTGATAACAAAAATCACAATGCTCAAATTATTAATTTTGACGGAACAATTTATGATAACTATGAACCA
GGCTTACGTAACAAAGTGATTAAAGACGTCGCTAAAAATGGCTTGAAGCGTAAATTTAAAAAATAA

Upstream 100 bases:

>100_bases
TTAGCGGGAGATTGGCACCACCACTGGTTTTTAAATGCTGATTTAATTGACCATCAACAAATGTCTAAGGGCGACAACTA
GAAATTAAAGGAGAAATACA

Downstream 100 bases:

>100_bases
ATGAAAAAATTACTGACAGATTAGTCAGTAATTTTTATATTTACAATCTATTCGTAAAAAAACCTTAATATTTATGATAA
AATAATTTTATGGAAAAAGA

Product: carbonyl reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKTLITGANKGIGFALAQNLGHRGYEVLVGARNETRGQEAVEKLKAEGINAEFVKVDLDDLNQLTSLSALTDIDLLINNA
GISGNIHSDKGHLDMEKSAFDYSNSDLEETIKTNFLGTHAVITELLPHSLTENAKIINITVPVSQEYWMPLAYVTSKAAQ
NAMTFAFGHQFKKDKSQKQIFAVMPGAVATDLNGAKVGDSPFVKSPEETAQMISKFIFDNKNHNAQIINFDGTIYDNYEP
GLRNKVIKDVAKNGLKRKFKK

Sequences:

>Translated_261_residues
MKTLITGANKGIGFALAQNLGHRGYEVLVGARNETRGQEAVEKLKAEGINAEFVKVDLDDLNQLTSLSALTDIDLLINNA
GISGNIHSDKGHLDMEKSAFDYSNSDLEETIKTNFLGTHAVITELLPHSLTENAKIINITVPVSQEYWMPLAYVTSKAAQ
NAMTFAFGHQFKKDKSQKQIFAVMPGAVATDLNGAKVGDSPFVKSPEETAQMISKFIFDNKNHNAQIINFDGTIYDNYEP
GLRNKVIKDVAKNGLKRKFKK
>Mature_261_residues
MKTLITGANKGIGFALAQNLGHRGYEVLVGARNETRGQEAVEKLKAEGINAEFVKVDLDDLNQLTSLSALTDIDLLINNA
GISGNIHSDKGHLDMEKSAFDYSNSDLEETIKTNFLGTHAVITELLPHSLTENAKIINITVPVSQEYWMPLAYVTSKAAQ
NAMTFAFGHQFKKDKSQKQIFAVMPGAVATDLNGAKVGDSPFVKSPEETAQMISKFIFDNKNHNAQIINFDGTIYDNYEP
GLRNKVIKDVAKNGLKRKFKK

Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4502599, Length=261, Percent_Identity=29.1187739463602, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4502601, Length=146, Percent_Identity=36.3013698630137, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558006, Length=226, Percent_Identity=27.4336283185841, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28718; Mature: 28718

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLITGANKGIGFALAQNLGHRGYEVLVGARNETRGQEAVEKLKAEGINAEFVKVDLDD
CCCEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEHHH
LNQLTSLSALTDIDLLINNAGISGNIHSDKGHLDMEKSAFDYSNSDLEETIKTNFLGTHA
HHHHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCCHHHCCCCCCHHHHHHHHHCCHHHH
VITELLPHSLTENAKIINITVPVSQEYWMPLAYVTSKAAQNAMTFAFGHQFKKDKSQKQI
HHHHHHHHHHCCCCEEEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEE
FAVMPGAVATDLNGAKVGDSPFVKSPEETAQMISKFIFDNKNHNAQIINFDGTIYDNYEP
EEECCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCC
GLRNKVIKDVAKNGLKRKFKK
CHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTLITGANKGIGFALAQNLGHRGYEVLVGARNETRGQEAVEKLKAEGINAEFVKVDLDD
CCCEECCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEEHHH
LNQLTSLSALTDIDLLINNAGISGNIHSDKGHLDMEKSAFDYSNSDLEETIKTNFLGTHA
HHHHHHHHHHHHHHHEEECCCCCCCEECCCCCCCCCHHHCCCCCCHHHHHHHHHCCHHHH
VITELLPHSLTENAKIINITVPVSQEYWMPLAYVTSKAAQNAMTFAFGHQFKKDKSQKQI
HHHHHHHHHHCCCCEEEEEEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEE
FAVMPGAVATDLNGAKVGDSPFVKSPEETAQMISKFIFDNKNHNAQIINFDGTIYDNYEP
EEECCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCC
GLRNKVIKDVAKNGLKRKFKK
CHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA