Definition Lactococcus lactis subsp. cremoris MG1363, complete genome.
Accession NC_009004
Length 2,529,478

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The map label for this gene is vdlC [H]

Identifier: 125622966

GI number: 125622966

Start: 82640

End: 83464

Strand: Reverse

Name: vdlC [H]

Synonym: llmg_0087

Alternate gene names: 125622966

Gene position: 83464-82640 (Counterclockwise)

Preceding gene: 125622968

Following gene: 125622964

Centisome position: 3.3

GC content: 41.45

Gene sequence:

>825_bases
ATGAAAACAGTTATTATCACAGGAGCCTCTAATGGAATGGGCTATGAAGCAGCCAAAGTCTTTGCAAGTAAAGGTTGGAA
AGTATTCGCTGGTGCTCGACGTGTCGAAAAGATTCCGACCGATCAAAATATTGTCGGGCTAAAACTTGACGTCACAGATT
CTGCTTCTAATCATGCTTTTATCGCTGAAATCCTGAAACAAACACAGCAAATCGACGTACTTATCAATAACGCTGGCTAT
GGTGAGTTTGGTCCAGCCGAAGAAATTCCAATGGAAAATGTCCGTAAGCAATTTGAAACGAATTTCTTTGGCGCTGTGGA
GCTAACTCAGCTTGTTCTGCCTACGATGCGTGCTCAAAAATCTGGGCGAATTATTAATATTTCATCTATTGGTGGCGATT
TGTATATTCCTTTGGGAAGTTATTATCATGCAACAAAAGCTGCTCTTCAACAATGGAGCGATGCACTGGATGTTGAAATC
AAGGACTTTGGTGCACAATCAATCATTATACAACCTGGCGGAACTGCGTCCAGCTGGGGCGAGATTGCCATAGGAAATGC
GCTTAAAAACTTGAAAAAAGATAGTTTTTATCAACCATTAGTTGAAAAGATACAAGGCGCACTTTCTGGTAATGCTTCCG
TGGGGGCGACTTCTCTTGACCTTGCTGAACTTTTTTATAAATCGGCAACTGACCAAAATCCAAAACGTCGTTATTTCAAC
TCATTTGGTGATCGAGCAGTCGTTCATATTGCGCGAGCTCATCCAAGATTATTCAGTCGACTGGCTACTTTTATGCTTAA
TCGTGTCGCTAAAAAGAAAGCCTAA

Upstream 100 bases:

>100_bases
TTTTAAAAAAACTTTATACTTGACAAGTGAATGCTTATTCAGTTATAATCATTAAATAAAAATAAATGAACGTTCATTTA
ACTAAAAAAGGAAAAATATT

Downstream 100 bases:

>100_bases
GCCTATCAACTGTATGACTTTGTAGTCATTCAATAAAAAGTTAATATATTAATTTCCCGAGATATAAGATTTAAAAAAAA
TAAGCAGAAATTTAAAAAGC

Product: putative short-chain type dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKTVIITGASNGMGYEAAKVFASKGWKVFAGARRVEKIPTDQNIVGLKLDVTDSASNHAFIAEILKQTQQIDVLINNAGY
GEFGPAEEIPMENVRKQFETNFFGAVELTQLVLPTMRAQKSGRIINISSIGGDLYIPLGSYYHATKAALQQWSDALDVEI
KDFGAQSIIIQPGGTASSWGEIAIGNALKNLKKDSFYQPLVEKIQGALSGNASVGATSLDLAELFYKSATDQNPKRRYFN
SFGDRAVVHIARAHPRLFSRLATFMLNRVAKKKA

Sequences:

>Translated_274_residues
MKTVIITGASNGMGYEAAKVFASKGWKVFAGARRVEKIPTDQNIVGLKLDVTDSASNHAFIAEILKQTQQIDVLINNAGY
GEFGPAEEIPMENVRKQFETNFFGAVELTQLVLPTMRAQKSGRIINISSIGGDLYIPLGSYYHATKAALQQWSDALDVEI
KDFGAQSIIIQPGGTASSWGEIAIGNALKNLKKDSFYQPLVEKIQGALSGNASVGATSLDLAELFYKSATDQNPKRRYFN
SFGDRAVVHIARAHPRLFSRLATFMLNRVAKKKA
>Mature_274_residues
MKTVIITGASNGMGYEAAKVFASKGWKVFAGARRVEKIPTDQNIVGLKLDVTDSASNHAFIAEILKQTQQIDVLINNAGY
GEFGPAEEIPMENVRKQFETNFFGAVELTQLVLPTMRAQKSGRIINISSIGGDLYIPLGSYYHATKAALQQWSDALDVEI
KDFGAQSIIIQPGGTASSWGEIAIGNALKNLKKDSFYQPLVEKIQGALSGNASVGATSLDLAELFYKSATDQNPKRRYFN
SFGDRAVVHIARAHPRLFSRLATFMLNRVAKKKA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=185, Percent_Identity=36.2162162162162, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=32.9842931937173, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI7706318, Length=172, Percent_Identity=32.5581395348837, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI223718074, Length=260, Percent_Identity=28.8461538461538, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI40548397, Length=256, Percent_Identity=30.078125, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI214010158, Length=256, Percent_Identity=30.078125, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI214010156, Length=256, Percent_Identity=30.078125, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI22758144, Length=256, Percent_Identity=30.078125, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI119392083, Length=186, Percent_Identity=32.258064516129, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI157739938, Length=184, Percent_Identity=29.3478260869565, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI44680136, Length=186, Percent_Identity=31.1827956989247, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI44680133, Length=186, Percent_Identity=31.1827956989247, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI17738292, Length=186, Percent_Identity=31.1827956989247, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI4504503, Length=185, Percent_Identity=31.3513513513514, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI22507405, Length=181, Percent_Identity=31.4917127071823, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=217, Percent_Identity=28.110599078341, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7705855, Length=178, Percent_Identity=30.3370786516854, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4503817, Length=188, Percent_Identity=25.531914893617, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI166795268, Length=202, Percent_Identity=29.7029702970297, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786701, Length=176, Percent_Identity=36.3636363636364, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=32.9545454545455, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786812, Length=176, Percent_Identity=30.1136363636364, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082100, Length=180, Percent_Identity=32.2222222222222, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787335, Length=178, Percent_Identity=30.8988764044944, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI2367365, Length=179, Percent_Identity=31.2849162011173, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787905, Length=144, Percent_Identity=32.6388888888889, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082160, Length=185, Percent_Identity=30.8108108108108, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=217, Percent_Identity=33.1797235023041, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71997402, Length=195, Percent_Identity=34.8717948717949, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=200, Percent_Identity=31.5, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=197, Percent_Identity=33.502538071066, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=190, Percent_Identity=33.6842105263158, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17559104, Length=217, Percent_Identity=30.4147465437788, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=198, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17570069, Length=195, Percent_Identity=33.8461538461538, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=192, Percent_Identity=31.25, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115534660, Length=182, Percent_Identity=28.021978021978, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=211, Percent_Identity=29.8578199052133, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=196, Percent_Identity=31.1224489795918, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=198, Percent_Identity=26.2626262626263, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=227, Percent_Identity=29.9559471365639, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=217, Percent_Identity=29.4930875576037, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=190, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17557780, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=225, Percent_Identity=28, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562906, Length=199, Percent_Identity=25.1256281407035, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=185, Percent_Identity=25.9459459459459, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=194, Percent_Identity=28.3505154639175, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=175, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=212, Percent_Identity=34.9056603773585, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322067, Length=188, Percent_Identity=30.8510638297872, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319635, Length=189, Percent_Identity=30.6878306878307, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=30.3964757709251, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24651139, Length=191, Percent_Identity=30.3664921465969, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=181, Percent_Identity=32.5966850828729, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24580925, Length=192, Percent_Identity=29.6875, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=181, Percent_Identity=29.2817679558011, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=189, Percent_Identity=30.6878306878307, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24640442, Length=219, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007238, Length=176, Percent_Identity=31.8181818181818, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007236, Length=188, Percent_Identity=31.3829787234043, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=178, Percent_Identity=32.0224719101124, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643142, Length=167, Percent_Identity=31.7365269461078, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45553409, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647948, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24647946, Length=138, Percent_Identity=32.6086956521739, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29918; Mature: 29918

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MKTVIITGASNGMGYEAAKVFASKGWKVFAGARRVEKIPTDQNIVGLKLDVTDSASNHAF
CCEEEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHCCCCCCEEEEEEEECCCCCCHHH
IAEILKQTQQIDVLINNAGYGEFGPAEEIPMENVRKQFETNFFGAVELTQLVLPTMRAQK
HHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
SGRIINISSIGGDLYIPLGSYYHATKAALQQWSDALDVEIKDFGAQSIIIQPGGTASSWG
CCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCC
EIAIGNALKNLKKDSFYQPLVEKIQGALSGNASVGATSLDLAELFYKSATDQNPKRRYFN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
SFGDRAVVHIARAHPRLFSRLATFMLNRVAKKKA
HCCCHHEEHHHHHCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTVIITGASNGMGYEAAKVFASKGWKVFAGARRVEKIPTDQNIVGLKLDVTDSASNHAF
CCEEEEEECCCCCCHHHHHHHHHCCCEEECCCHHHHHCCCCCCEEEEEEEECCCCCCHHH
IAEILKQTQQIDVLINNAGYGEFGPAEEIPMENVRKQFETNFFGAVELTQLVLPTMRAQK
HHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
SGRIINISSIGGDLYIPLGSYYHATKAALQQWSDALDVEIKDFGAQSIIIQPGGTASSWG
CCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCC
EIAIGNALKNLKKDSFYQPLVEKIQGALSGNASVGATSLDLAELFYKSATDQNPKRRYFN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHH
SFGDRAVVHIARAHPRLFSRLATFMLNRVAKKKA
HCCCHHEEHHHHHCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9139899; 9252185 [H]