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The map label for this gene is supH [H]

Identifier: 125622963

GI number: 125622963

Start: 78941

End: 79753

Strand: Reverse

Name: supH [H]

Synonym: llmg_0084

Alternate gene names: 125622963

Gene position: 79753-78941 (Counterclockwise)

Preceding gene: 125622964

Following gene: 125622962

Centisome position: 3.15

GC content: 37.88

Gene sequence:

>813_bases
ATGACTAAAAACTTAAAACTTTTTGCTACAGATATGGACGGAACTTTTCTGCGCAATGACCATTCTTATAATCATAAAAA
ACTTGCGGAACTAATTAAAGAAATTCAAGATAGAAATCTTCTTTTTGCCGCTTCTTCTGGCCGTTCTTTACTTGGTTTAA
CAGAGGTTTTTGCTGAATATAAAGACCAGATGGCTTTTGTCGCCGAAAACGGTGGCGTCGTTGCTTATAAAGGAGAAATC
CTCTTTGCCAAAGATTTGACTGTTGCCCAAACGCAAGAATTGATTGATGACTTGCAAGAAATGCCATTCAGTCCTAAAAG
TGATTATCTGATTTCTGGTCTCAAAGGGGCTTATTACCCTGAAGGAATTTCTAAAGAATACCTGACACATGCCAAACTTT
ACTATCCTAACTGTCAACTTTATCACCAATTAGATGAAATTGATGACAAACTTCTCAAAGTTACCACAAACTTTCCTGAG
GACCATGTTCGGGACTGTGAGCAATGGATTACTGACCGTCTTTCTTTTGTCAGAGCGACAACGACTGGTTTTACTAGTAT
TGATATCGTACCAAATGGAATTTCTAAAGCCTCCGGTCTGGCACATTTGTTGGCACATTTTAATTGGCTCCCTGAAAATT
TAGCTGTTTTTGGTGACCAAATGAATGATTTGGAAATGTTTGAATACGCAGGTTCTTCTTTTGCTGTCAGCAACGCAGCA
CCTGAAATTCTTGCTCTGGCTGACAAAGTCATTCTTTCTAATGACGAAGATGCTGTCCTTGTTGAAATTGAAAATATTTT
AAATGAGCAGTAA

Upstream 100 bases:

>100_bases
AAGGAACTGACAGCTTTACTGGCATTTCTTGTCAGTAAAATTTACTGACAGAACTAATTTTCATTCATTGATAGCATCAT
CAATGAATTAGGGAGAAGTC

Downstream 100 bases:

>100_bases
ATTTCTTCAATAGATTATCTATTGTGAAAAAAAGTGACTATCTGGTCACTTTTTTTGTTATAATTTTAATGAGATATTAT
TTGATTTGGAGAAAATAAAA

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTKNLKLFATDMDGTFLRNDHSYNHKKLAELIKEIQDRNLLFAASSGRSLLGLTEVFAEYKDQMAFVAENGGVVAYKGEI
LFAKDLTVAQTQELIDDLQEMPFSPKSDYLISGLKGAYYPEGISKEYLTHAKLYYPNCQLYHQLDEIDDKLLKVTTNFPE
DHVRDCEQWITDRLSFVRATTTGFTSIDIVPNGISKASGLAHLLAHFNWLPENLAVFGDQMNDLEMFEYAGSSFAVSNAA
PEILALADKVILSNDEDAVLVEIENILNEQ

Sequences:

>Translated_270_residues
MTKNLKLFATDMDGTFLRNDHSYNHKKLAELIKEIQDRNLLFAASSGRSLLGLTEVFAEYKDQMAFVAENGGVVAYKGEI
LFAKDLTVAQTQELIDDLQEMPFSPKSDYLISGLKGAYYPEGISKEYLTHAKLYYPNCQLYHQLDEIDDKLLKVTTNFPE
DHVRDCEQWITDRLSFVRATTTGFTSIDIVPNGISKASGLAHLLAHFNWLPENLAVFGDQMNDLEMFEYAGSSFAVSNAA
PEILALADKVILSNDEDAVLVEIENILNEQ
>Mature_269_residues
TKNLKLFATDMDGTFLRNDHSYNHKKLAELIKEIQDRNLLFAASSGRSLLGLTEVFAEYKDQMAFVAENGGVVAYKGEIL
FAKDLTVAQTQELIDDLQEMPFSPKSDYLISGLKGAYYPEGISKEYLTHAKLYYPNCQLYHQLDEIDDKLLKVTTNFPED
HVRDCEQWITDRLSFVRATTTGFTSIDIVPNGISKASGLAHLLAHFNWLPENLAVFGDQMNDLEMFEYAGSSFAVSNAAP
EILALADKVILSNDEDAVLVEIENILNEQ

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=270, Percent_Identity=30.7407407407407, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI87081790, Length=268, Percent_Identity=28.7313432835821, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 30332; Mature: 30200

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNLKLFATDMDGTFLRNDHSYNHKKLAELIKEIQDRNLLFAASSGRSLLGLTEVFAEY
CCCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
KDQMAFVAENGGVVAYKGEILFAKDLTVAQTQELIDDLQEMPFSPKSDYLISGLKGAYYP
HHHEEEEECCCCEEEEECCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
EGISKEYLTHAKLYYPNCQLYHQLDEIDDKLLKVTTNFPEDHVRDCEQWITDRLSFVRAT
CCCCHHHHHHCEEECCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TTGFTSIDIVPNGISKASGLAHLLAHFNWLPENLAVFGDQMNDLEMFEYAGSSFAVSNAA
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCEEECCCC
PEILALADKVILSNDEDAVLVEIENILNEQ
HHHHHHHHHHHCCCCCCEEEEEEHHHCCCC
>Mature Secondary Structure 
TKNLKLFATDMDGTFLRNDHSYNHKKLAELIKEIQDRNLLFAASSGRSLLGLTEVFAEY
CCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHH
KDQMAFVAENGGVVAYKGEILFAKDLTVAQTQELIDDLQEMPFSPKSDYLISGLKGAYYP
HHHEEEEECCCCEEEEECCEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
EGISKEYLTHAKLYYPNCQLYHQLDEIDDKLLKVTTNFPEDHVRDCEQWITDRLSFVRAT
CCCCHHHHHHCEEECCCHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHH
TTGFTSIDIVPNGISKASGLAHLLAHFNWLPENLAVFGDQMNDLEMFEYAGSSFAVSNAA
CCCCEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCCEEECCCC
PEILALADKVILSNDEDAVLVEIENILNEQ
HHHHHHHHHHHCCCCCCEEEEEEHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]