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The map label for this gene is trpS [H]

Identifier: 125622958

GI number: 125622958

Start: 73937

End: 74962

Strand: Reverse

Name: trpS [H]

Synonym: llmg_0079

Alternate gene names: 125622958

Gene position: 74962-73937 (Counterclockwise)

Preceding gene: 125622962

Following gene: 125622957

Centisome position: 2.96

GC content: 40.64

Gene sequence:

>1026_bases
ATGACAAAACCAACTATTTTAACCGGCGATCGTCCAACGGGAAAACTTCATATTGGCCACTATGTTGGCTCCCTACAAAA
TCGTGTCAAGATGCAAAATGAAGATAAATACAATATGTTTGTTTTCTTAGCTGACCAACAAGCTTTGACTGACCATGCCA
AAGACCCTGAACTTATTCGTCAATCAGTCGGCGATGTTGCTCTCGACTATTTAGCAGCAGGACTTGACCCTGAAAAATCA
ACTATTTTTATTCAAAGTCAAATTCCCGAATTAGCTGAACTTTCAATGTATTATATGAACTTAGTTTCACTTGCTCGACT
TGAACGCAACCCTACTGTAAAAACAGAAATTGCCCAAAAAGCTTTTGGGGAATCAATTCCTGCGGGATTCTTGGTTTACC
CTGTTTCTCAAGCTGCTGATATTACTGCTTTCAAAGCCACTCATGTCCCAGTCGGAAATGACCAAAAACCAATGATTGAG
CAAACACGCGAGATTGTTCGCTCATTCAACAATGCTTACCATACTGATATTTTGGTTGAACCAGAAGGAATTTACCCTGA
GAATGAAGCAGCCGGTCGCTTGCCTGGACTTGATGGAAATGCCAAAATGTCTAAATCACTCGGTAACGGAATTTTCCTTG
CTGATGACATGGATACACTCAAGAAAAAAGTCATGTCAATGTATACTGACCCTGACCACATCAAAGTGGAAGATCCTGGT
AAAATCGAAGGGAACATGGTCTTCCATTATCTTGATGTTTTCGGTAAAGCTGAAGATGCTGAACAAATCGCCGAAATGAA
AGCCCAATATCAAGCGGGTGGTCTTGGCGATGTGAAGACAAAACGTTTCCTTCTTGAAGTGCTTGAACGTGAACTTTCAC
CAATTCGCGAACGACGTATTGAATTTGCGCAAAATATGGATTATGTTTACGATATGCTCAAGGCTGGTTCTTTAAAAGCC
GAAGCTGTAGCTAGCCAAACGCTTGATGAAGTCAAGAATGCAATGGGAATCAATTATTTTAGGTAA

Upstream 100 bases:

>100_bases
TTTATAGTTCTACGGGTGCTTTTTTTATTTTTTTATTAGGTGTAAACCAGTTTACACTGTTCAAATAAACAAACTAAACT
CATCTACAAAGGAGAAAAAA

Downstream 100 bases:

>100_bases
TTCATTGTTTTGACACCTTATTGAAATTTATGTTATTTTCTGTTATATTAATCTTGTTTAATAGACTATAAAATTTCAAA
GAGGTTCTGCTTATGGAAAG

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTKPTILTGDRPTGKLHIGHYVGSLQNRVKMQNEDKYNMFVFLADQQALTDHAKDPELIRQSVGDVALDYLAAGLDPEKS
TIFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEIAQKAFGESIPAGFLVYPVSQAADITAFKATHVPVGNDQKPMIE
QTREIVRSFNNAYHTDILVEPEGIYPENEAAGRLPGLDGNAKMSKSLGNGIFLADDMDTLKKKVMSMYTDPDHIKVEDPG
KIEGNMVFHYLDVFGKAEDAEQIAEMKAQYQAGGLGDVKTKRFLLEVLERELSPIRERRIEFAQNMDYVYDMLKAGSLKA
EAVASQTLDEVKNAMGINYFR

Sequences:

>Translated_341_residues
MTKPTILTGDRPTGKLHIGHYVGSLQNRVKMQNEDKYNMFVFLADQQALTDHAKDPELIRQSVGDVALDYLAAGLDPEKS
TIFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEIAQKAFGESIPAGFLVYPVSQAADITAFKATHVPVGNDQKPMIE
QTREIVRSFNNAYHTDILVEPEGIYPENEAAGRLPGLDGNAKMSKSLGNGIFLADDMDTLKKKVMSMYTDPDHIKVEDPG
KIEGNMVFHYLDVFGKAEDAEQIAEMKAQYQAGGLGDVKTKRFLLEVLERELSPIRERRIEFAQNMDYVYDMLKAGSLKA
EAVASQTLDEVKNAMGINYFR
>Mature_340_residues
TKPTILTGDRPTGKLHIGHYVGSLQNRVKMQNEDKYNMFVFLADQQALTDHAKDPELIRQSVGDVALDYLAAGLDPEKST
IFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEIAQKAFGESIPAGFLVYPVSQAADITAFKATHVPVGNDQKPMIEQ
TREIVRSFNNAYHTDILVEPEGIYPENEAAGRLPGLDGNAKMSKSLGNGIFLADDMDTLKKKVMSMYTDPDHIKVEDPGK
IEGNMVFHYLDVFGKAEDAEQIAEMKAQYQAGGLGDVKTKRFLLEVLERELSPIRERRIEFAQNMDYVYDMLKAGSLKAE
AVASQTLDEVKNAMGINYFR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=341, Percent_Identity=29.9120234604106, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI41352700, Length=173, Percent_Identity=36.9942196531792, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1789786, Length=340, Percent_Identity=34.4117647058824, Blast_Score=163, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71982800, Length=347, Percent_Identity=30.835734870317, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71982793, Length=348, Percent_Identity=30.7471264367816, Blast_Score=136, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320474, Length=356, Percent_Identity=27.5280898876405, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24666151, Length=337, Percent_Identity=32.0474777448071, Blast_Score=151, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 38120; Mature: 37989

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPTILTGDRPTGKLHIGHYVGSLQNRVKMQNEDKYNMFVFLADQQALTDHAKDPELIR
CCCCCEEECCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHCCCCHHHHH
QSVGDVALDYLAAGLDPEKSTIFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEIAQK
HHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AFGESIPAGFLVYPVSQAADITAFKATHVPVGNDQKPMIEQTREIVRSFNNAYHTDILVE
HHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEC
PEGIYPENEAAGRLPGLDGNAKMSKSLGNGIFLADDMDTLKKKVMSMYTDPDHIKVEDPG
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCEEECCCC
KIEGNMVFHYLDVFGKAEDAEQIAEMKAQYQAGGLGDVKTKRFLLEVLERELSPIRERRI
CCCCCCCEEHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EFAQNMDYVYDMLKAGSLKAEAVASQTLDEVKNAMGINYFR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TKPTILTGDRPTGKLHIGHYVGSLQNRVKMQNEDKYNMFVFLADQQALTDHAKDPELIR
CCCCEEECCCCCCEEEHHHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHCCCCHHHHH
QSVGDVALDYLAAGLDPEKSTIFIQSQIPELAELSMYYMNLVSLARLERNPTVKTEIAQK
HHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AFGESIPAGFLVYPVSQAADITAFKATHVPVGNDQKPMIEQTREIVRSFNNAYHTDILVE
HHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEC
PEGIYPENEAAGRLPGLDGNAKMSKSLGNGIFLADDMDTLKKKVMSMYTDPDHIKVEDPG
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCEEECCCC
KIEGNMVFHYLDVFGKAEDAEQIAEMKAQYQAGGLGDVKTKRFLLEVLERELSPIRERRI
CCCCCCCEEHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EFAQNMDYVYDMLKAGSLKAEAVASQTLDEVKNAMGINYFR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]