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The map label for this gene is ytcJ [H]

Identifier: 124486505

GI number: 124486505

Start: 1726815

End: 1728416

Strand: Reverse

Name: ytcJ [H]

Synonym: Mlab_1693

Alternate gene names: 124486505

Gene position: 1728416-1726815 (Counterclockwise)

Preceding gene: 124486508

Following gene: 124486504

Centisome position: 95.76

GC content: 58.8

Gene sequence:

>1602_bases
ATGACAACAATACCGAACGAAAAAATAACTGCGTTCACCGGCGGCAAGATCCTCACCATGGATCCAGACCGCGGCCACGC
TGAGACAGTAATAATTCAAAACGGCCGGATCAAGGATATCGGCGATGCAGAACTCATAAATCAGTATCCAAACGCCGCGG
TCGTCGACCTCTCCGGCCGGACCCTTATACCGGGCTTCATCGATTCGCATAACCACCTCTCCTCCTTCGGCTGTTTTTTC
CCGGAATGGGCAAACCTGATTGGGATCACCGATGAGACGGCGGTCTTTGCAGCTCTGGCCGAACATGAAAAAGAGAATCT
GGGGCCAGGCTGGCTGGTCGGATTCGGCTGGTTCGATGCACAGTGCGGGGGAAAAGAATTCACCCGGGCAGATCTCGACG
CGATCTATCCCGACCGTCCGGTCGTTCTGATCCAGGCGACATTTCATAAAAGCGTTGTCAACAGCAAAGCGCTGGAACTC
CTCGGCATCGAATCATCGTCGCCGGATCCGCGGTGCGGGATCATTCAGAGGGATCAAAACGGTGTTCCAACCGGCATCCT
GATCGAAGAGGCCCAGGTCCCGGTGTTTCAAACGATCATGGCGGCAGACACCAGGCGTCATGCCGATCTGATCGAGGCCC
GGGCGAAGGAACTTCTGCCGTTTGGGATCACTGCGGTCCATGATCCGGGCGTCACCCCGGCAGCCGAGGCCGCCTACCGT
CTGCTCTATGACGAAGGCCGGCTTCCCGTTTCGGTCCTGATGATGCCGCACGGAAGCGCCGTGCTCGATAATGATCTCGG
CTCCCGTCTCGCAGGTCCCTCTACCGGAGCGGGAGACGAAAAGCTTCGGACCGGTCCTGCGAAACTTTTCGCCGACGGGG
CAACCTCCGAGACCGTCGCTTTTGCGATGAAGATGCACGGCCAGGTCATCACCAGCGGAAAATACCGGGACGACTTCGCC
GATGTCTTGTGCACGGCCGCCAGAAACGGATGGCAGACCTGCGTCCATTCGTTTGGGAACGCCACGACCGACGCCGTACT
CGATGCCTACGAACAGGCGGCAAAGGAAACGCCCGCCGGCTTCGTGCTTCGGCCCCGTCTCGAACATGTGACGCTTCTTT
CGAACAGCCAGATCGAGCGGCTTTCCAAAATGAACGCCTGCGTCTCCGTCCAGCCGCAGTTCCTTGTTCGGGGCGAGGGC
ATGAAGCGTGCTCCTCTCGACGAAGGAAAATGGTTTGCATACGGCGATCTTTCCCGTTCCGGCGTAGTTGTTGCGGCAAG
CAGCGATGATCCCGGAGGATTCATGGATGCCCGCGATCCGATCAAATGCTCGGTCATGGGCTCGACGATGAGCGCCGGGG
ACGGCAAAACGATCTTCCCCGAGCAGGTCATGCCGTTTGTCGAGTGGCTGCGTATCTACACTGCGGGCAGTGCCTTTGCC
GGAGGACAGGAGAATGAGAGGGGCATGCTGAAAAAAGGCATGGTCGCGGATCTCGTGCTCCTGAAAGGGGAACTCGACCC
CCAAAATCCCCCGGTCGTCGATGAGACCTGGAAGGACGGCCGGCTCGTCTACCAACGGGAGGCCCCGGAGAAAACCGTAT
GA

Upstream 100 bases:

>100_bases
AGTTACTATGCAGTAACTTTAATTAGTACACAGTATAATTAGTAAATTGGATTGTGCAGCGTATCCGGGCAGTTTGCTGG
AGAGACAATCCGTGATCACC

Downstream 100 bases:

>100_bases
CCCCGGACCCCGTTCCCCTTTCGAAAAAGGCCGTCCGCATCCTGCGGGCGAAAGGCATCCTTTCCGGAACGATCCCGGTT
CTGATCATGGGCGTGATCCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MTTIPNEKITAFTGGKILTMDPDRGHAETVIIQNGRIKDIGDAELINQYPNAAVVDLSGRTLIPGFIDSHNHLSSFGCFF
PEWANLIGITDETAVFAALAEHEKENLGPGWLVGFGWFDAQCGGKEFTRADLDAIYPDRPVVLIQATFHKSVVNSKALEL
LGIESSSPDPRCGIIQRDQNGVPTGILIEEAQVPVFQTIMAADTRRHADLIEARAKELLPFGITAVHDPGVTPAAEAAYR
LLYDEGRLPVSVLMMPHGSAVLDNDLGSRLAGPSTGAGDEKLRTGPAKLFADGATSETVAFAMKMHGQVITSGKYRDDFA
DVLCTAARNGWQTCVHSFGNATTDAVLDAYEQAAKETPAGFVLRPRLEHVTLLSNSQIERLSKMNACVSVQPQFLVRGEG
MKRAPLDEGKWFAYGDLSRSGVVVAASSDDPGGFMDARDPIKCSVMGSTMSAGDGKTIFPEQVMPFVEWLRIYTAGSAFA
GGQENERGMLKKGMVADLVLLKGELDPQNPPVVDETWKDGRLVYQREAPEKTV

Sequences:

>Translated_533_residues
MTTIPNEKITAFTGGKILTMDPDRGHAETVIIQNGRIKDIGDAELINQYPNAAVVDLSGRTLIPGFIDSHNHLSSFGCFF
PEWANLIGITDETAVFAALAEHEKENLGPGWLVGFGWFDAQCGGKEFTRADLDAIYPDRPVVLIQATFHKSVVNSKALEL
LGIESSSPDPRCGIIQRDQNGVPTGILIEEAQVPVFQTIMAADTRRHADLIEARAKELLPFGITAVHDPGVTPAAEAAYR
LLYDEGRLPVSVLMMPHGSAVLDNDLGSRLAGPSTGAGDEKLRTGPAKLFADGATSETVAFAMKMHGQVITSGKYRDDFA
DVLCTAARNGWQTCVHSFGNATTDAVLDAYEQAAKETPAGFVLRPRLEHVTLLSNSQIERLSKMNACVSVQPQFLVRGEG
MKRAPLDEGKWFAYGDLSRSGVVVAASSDDPGGFMDARDPIKCSVMGSTMSAGDGKTIFPEQVMPFVEWLRIYTAGSAFA
GGQENERGMLKKGMVADLVLLKGELDPQNPPVVDETWKDGRLVYQREAPEKTV
>Mature_532_residues
TTIPNEKITAFTGGKILTMDPDRGHAETVIIQNGRIKDIGDAELINQYPNAAVVDLSGRTLIPGFIDSHNHLSSFGCFFP
EWANLIGITDETAVFAALAEHEKENLGPGWLVGFGWFDAQCGGKEFTRADLDAIYPDRPVVLIQATFHKSVVNSKALELL
GIESSSPDPRCGIIQRDQNGVPTGILIEEAQVPVFQTIMAADTRRHADLIEARAKELLPFGITAVHDPGVTPAAEAAYRL
LYDEGRLPVSVLMMPHGSAVLDNDLGSRLAGPSTGAGDEKLRTGPAKLFADGATSETVAFAMKMHGQVITSGKYRDDFAD
VLCTAARNGWQTCVHSFGNATTDAVLDAYEQAAKETPAGFVLRPRLEHVTLLSNSQIERLSKMNACVSVQPQFLVRGEGM
KRAPLDEGKWFAYGDLSRSGVVVAASSDDPGGFMDARDPIKCSVMGSTMSAGDGKTIFPEQVMPFVEWLRIYTAGSAFAG
GQENERGMLKKGMVADLVLLKGELDPQNPPVVDETWKDGRLVYQREAPEKTV

Specific function: Catalyzes The Hydrolytic Cleavage Of A Subset Of L- Isoaspartyl (L-Beta-Aspartyl) Dipeptides. Used To Degrade Proteins Damaged By L-Isoaspartyl Residues Formation. The Best Substrate For The Enzyme Reported Thus Far Is Iso-Asp-Leu. [C]

COG id: COG1574

COG function: function code R; Predicted metal-dependent hydrolase with the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: 3.4.19.- [C]

Molecular weight: Translated: 57594; Mature: 57463

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIPNEKITAFTGGKILTMDPDRGHAETVIIQNGRIKDIGDAELINQYPNAAVVDLSGR
CCCCCCCCEEEEECCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEECCC
TLIPGFIDSHNHLSSFGCFFPEWANLIGITDETAVFAALAEHEKENLGPGWLVGFGWFDA
EECCCCCCCCCCHHHHCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCEEC
QCGGKEFTRADLDAIYPDRPVVLIQATFHKSVVNSKALELLGIESSSPDPRCGIIQRDQN
CCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHCCHHEEEEECCCCCCCCCCCEEEECCC
GVPTGILIEEAQVPVFQTIMAADTRRHADLIEARAKELLPFGITAVHDPGVTPAAEAAYR
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHH
LLYDEGRLPVSVLMMPHGSAVLDNDLGSRLAGPSTGAGDEKLRTGPAKLFADGATSETVA
HHHCCCCCCEEEEEECCCCEEECCCHHHHCCCCCCCCCCHHHCCCCHHEEECCCCHHHHH
FAMKMHGQVITSGKYRDDFADVLCTAARNGWQTCVHSFGNATTDAVLDAYEQAAKETPAG
HHHHHCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
FVLRPRLEHVTLLSNSQIERLSKMNACVSVQPQFLVRGEGMKRAPLDEGKWFAYGDLSRS
EEECCCCCEEEEECCHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCC
GVVVAASSDDPGGFMDARDPIKCSVMGSTMSAGDGKTIFPEQVMPFVEWLRIYTAGSAFA
CEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCC
GGQENERGMLKKGMVADLVLLKGELDPQNPPVVDETWKDGRLVYQREAPEKTV
CCCCCCCCHHHHCHHHEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TTIPNEKITAFTGGKILTMDPDRGHAETVIIQNGRIKDIGDAELINQYPNAAVVDLSGR
CCCCCCCEEEEECCEEEEECCCCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEEECCC
TLIPGFIDSHNHLSSFGCFFPEWANLIGITDETAVFAALAEHEKENLGPGWLVGFGWFDA
EECCCCCCCCCCHHHHCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCCCCEEEEECCEEC
QCGGKEFTRADLDAIYPDRPVVLIQATFHKSVVNSKALELLGIESSSPDPRCGIIQRDQN
CCCCCHHHHHHHHHCCCCCCEEEEEEHHHHHHHCCHHEEEEECCCCCCCCCCCEEEECCC
GVPTGILIEEAQVPVFQTIMAADTRRHADLIEARAKELLPFGITAVHDPGVTPAAEAAYR
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHH
LLYDEGRLPVSVLMMPHGSAVLDNDLGSRLAGPSTGAGDEKLRTGPAKLFADGATSETVA
HHHCCCCCCEEEEEECCCCEEECCCHHHHCCCCCCCCCCHHHCCCCHHEEECCCCHHHHH
FAMKMHGQVITSGKYRDDFADVLCTAARNGWQTCVHSFGNATTDAVLDAYEQAAKETPAG
HHHHHCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
FVLRPRLEHVTLLSNSQIERLSKMNACVSVQPQFLVRGEGMKRAPLDEGKWFAYGDLSRS
EEECCCCCEEEEECCHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCCCEEEEECCCCC
GVVVAASSDDPGGFMDARDPIKCSVMGSTMSAGDGKTIFPEQVMPFVEWLRIYTAGSAFA
CEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHCCCCCC
GGQENERGMLKKGMVADLVLLKGELDPQNPPVVDETWKDGRLVYQREAPEKTV
CCCCCCCCHHHHCHHHEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]