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The map label for this gene is cbiZ [H]

Identifier: 124486484

GI number: 124486484

Start: 1705265

End: 1706188

Strand: Reverse

Name: cbiZ [H]

Synonym: Mlab_1672

Alternate gene names: 124486484

Gene position: 1706188-1705265 (Counterclockwise)

Preceding gene: 124486485

Following gene: 124486479

Centisome position: 94.53

GC content: 56.6

Gene sequence:

>924_bases
ATGCGGTATTATCTGCGAAAGGATGTTTTGATCGTCAGAGGAAACTTTCGGGCGGCAAGCAACGGTGTGGACGGCGGCCT
TGCGGACGTCAGATCGATTCTGAACATCTCGGTCCCGCGGCTGTTTTCCGAGGATGCTTCCCGGCACATCAGCACTGTCT
CGATGCGGAATGGATTTCTCCATCCGTATTTCGGTCTTCTGACCGCTCTGCCGATCACGAACCTCTGCATCGCCCGCTAT
GACTACGTTACGGTTTTTGTGACCGCCGCCGTTTCAGACCGGAACCGGACGATCAACATCATCGTGACGTGCGAGCGTCC
GCTCACCGACGCCGCTTTGCTTGGGGCTATGATGACGGTCACCGAAGCGAAAATGCAGGTGATCACGGCGAGAAAAGTTC
CGGGCAGCGCTTTGTCCACGGACGCCGTGGTTGTGGCCTGCGAAAAAACGGACGGGATCCCGGAGGCGTTTGTGGGACCC
CTGACCGAGACCGGCATGCGGATCTCAAAAGCCGTGTCCCATGCCCTGACCGAGGCTCTTGTCCGGTTCGACAACTATCT
TCTCTCCACCTGGGGCGTGACCCGCGGCTGGTCCCGGGGAAACCCTGCGATCGTCAAACGGCACCGGCCGTCGTTTTTCA
TCTACAGCAGGTACGGGGGCGACCACTGGAACGAATGGATCCCGGAGGACTGTCCGTATTATCCGTGCCATAATTATGCC
GATCAGCAGTGCAGTTTTTGTTACTGCCCGCTTTACCCCTGCATGGACACGGAATACGGGCAGATGATCGAGACGCCTCA
CGGCGAGATCTGGAGCTGCATGGACTGCCGCTTAGTTCACGAACCACGGGTGGCGAATCATCTTCTCGCAAATCCCGAAG
CCGGTGTTTTGGAACTGAAATCGTTAAAAAAGAAAAATATTTAG

Upstream 100 bases:

>100_bases
CCCTGCTGGACCATGCAGCGTATCTCGGTAAAGAGCTGTATAAAGCGGAGCTTGCCCTGCGGTTTGGCAGAAGTTTCGAG
CAGGACGGGAACTTCTGACC

Downstream 100 bases:

>100_bases
AGACCGAGCTTTTTTGCAAGCTCTTCTAATGGGATGCCGTGAACCATTGCGGCCTCGCGAATGGTTTCGTTGTTTGCGAT
CGCGCAGCCGAGGCAGCCCA

Product: hypothetical protein

Products: NA

Alternate protein names: AdoCbi hydrolase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MRYYLRKDVLIVRGNFRAASNGVDGGLADVRSILNISVPRLFSEDASRHISTVSMRNGFLHPYFGLLTALPITNLCIARY
DYVTVFVTAAVSDRNRTINIIVTCERPLTDAALLGAMMTVTEAKMQVITARKVPGSALSTDAVVVACEKTDGIPEAFVGP
LTETGMRISKAVSHALTEALVRFDNYLLSTWGVTRGWSRGNPAIVKRHRPSFFIYSRYGGDHWNEWIPEDCPYYPCHNYA
DQQCSFCYCPLYPCMDTEYGQMIETPHGEIWSCMDCRLVHEPRVANHLLANPEAGVLELKSLKKKNI

Sequences:

>Translated_307_residues
MRYYLRKDVLIVRGNFRAASNGVDGGLADVRSILNISVPRLFSEDASRHISTVSMRNGFLHPYFGLLTALPITNLCIARY
DYVTVFVTAAVSDRNRTINIIVTCERPLTDAALLGAMMTVTEAKMQVITARKVPGSALSTDAVVVACEKTDGIPEAFVGP
LTETGMRISKAVSHALTEALVRFDNYLLSTWGVTRGWSRGNPAIVKRHRPSFFIYSRYGGDHWNEWIPEDCPYYPCHNYA
DQQCSFCYCPLYPCMDTEYGQMIETPHGEIWSCMDCRLVHEPRVANHLLANPEAGVLELKSLKKKNI
>Mature_307_residues
MRYYLRKDVLIVRGNFRAASNGVDGGLADVRSILNISVPRLFSEDASRHISTVSMRNGFLHPYFGLLTALPITNLCIARY
DYVTVFVTAAVSDRNRTINIIVTCERPLTDAALLGAMMTVTEAKMQVITARKVPGSALSTDAVVVACEKTDGIPEAFVGP
LTETGMRISKAVSHALTEALVRFDNYLLSTWGVTRGWSRGNPAIVKRHRPSFFIYSRYGGDHWNEWIPEDCPYYPCHNYA
DQQCSFCYCPLYPCMDTEYGQMIETPHGEIWSCMDCRLVHEPRVANHLLANPEAGVLELKSLKKKNI

Specific function: Converts adenosylcobinamide (AdoCbi) to adenosylcobyric acid (AdoCby), an intermediate of the de novo coenzyme B12 biosynthetic route [H]

COG id: COG1865

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CbiZ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002808 [H]

Pfam domain/function: PF01955 CbiZ [H]

EC number: =3.5.1.90 [H]

Molecular weight: Translated: 34392; Mature: 34392

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYYLRKDVLIVRGNFRAASNGVDGGLADVRSILNISVPRLFSEDASRHISTVSMRNGFL
CCCEEECCEEEEECCCEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHEEEHHCCCCC
HPYFGLLTALPITNLCIARYDYVTVFVTAAVSDRNRTINIIVTCERPLTDAALLGAMMTV
CHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHH
TEAKMQVITARKVPGSALSTDAVVVACEKTDGIPEAFVGPLTETGMRISKAVSHALTEAL
HHHHHHHEEECCCCCCCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
VRFDNYLLSTWGVTRGWSRGNPAIVKRHRPSFFIYSRYGGDHWNEWIPEDCPYYPCHNYA
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCC
DQQCSFCYCPLYPCMDTEYGQMIETPHGEIWSCMDCRLVHEPRVANHLLANPEAGVLELK
CCCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHCCEEECCCCHHHHHHCCCCCCHHHHH
SLKKKNI
HHHHCCC
>Mature Secondary Structure
MRYYLRKDVLIVRGNFRAASNGVDGGLADVRSILNISVPRLFSEDASRHISTVSMRNGFL
CCCEEECCEEEEECCCEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHEEEHHCCCCC
HPYFGLLTALPITNLCIARYDYVTVFVTAAVSDRNRTINIIVTCERPLTDAALLGAMMTV
CHHHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHHHHH
TEAKMQVITARKVPGSALSTDAVVVACEKTDGIPEAFVGPLTETGMRISKAVSHALTEAL
HHHHHHHEEECCCCCCCCCCCEEEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHH
VRFDNYLLSTWGVTRGWSRGNPAIVKRHRPSFFIYSRYGGDHWNEWIPEDCPYYPCHNYA
HHHHHHHHHHCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCC
DQQCSFCYCPLYPCMDTEYGQMIETPHGEIWSCMDCRLVHEPRVANHLLANPEAGVLELK
CCCCCEEEECCCCCCCCCCHHHHCCCCCCHHHHHCCEEECCCCHHHHHHCCCCCCHHHHH
SLKKKNI
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]