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The map label for this gene is mtnU [H]

Identifier: 124486249

GI number: 124486249

Start: 1463173

End: 1463919

Strand: Reverse

Name: mtnU [H]

Synonym: Mlab_1433

Alternate gene names: 124486249

Gene position: 1463919-1463173 (Counterclockwise)

Preceding gene: 124486250

Following gene: 124486247

Centisome position: 81.11

GC content: 56.09

Gene sequence:

>747_bases
ATGCGAGTCTGTTGTGCCCAGCTGATTCAGGTGTGGGATGATGTTGATGCTGCTTTTGCGAAAGCAGATGTTTTTCTTAA
AGAATATTCCGGGACAGCAGATATAGTGGTGTTTTCCGAGCAGTTTGCGACCGGATGGCGACCCGCCCCCGCTCCGGTCT
CGGCTGAGGATGTGAAATGCCGGTGGCTTGCCCTCGCAGCGAAGCATAATGTCTGCGTTGTTGGTTCCTATCAGAAAGTG
GAAGCTGGCGGGTTGCCGCAGAATACTATGCTCGTGTGCGGTCCGTCAGGCGAGGTCATTGCCGAGTATTCCAAGATGTA
TCTGTTTGTGCCGGGTAAGGAGGATCGGTGTTTTTCACCGGGTGCCCGGCCGGTGACGTTTGAGTATGGCGGGGTGAAGT
TTGGGTGTGCGATCTGTTTTGATCTGCGGTTTCCCGAGTTATTCCGCGCGTATCTGAAGTTGGGGTGCGAGTGCGTTCTG
GTTCAGGCAGCCTGGCCTGCGGCACGGGTCGCGGATTGGGAGCTTTTACTTCGGGCCCGGGCATTGGAGAACAGGGGATT
TGTTTTCGGGGCTGCGTGTATGGGATATGATCCCGCGTCGGGAACGGATTACTGTGGGCGGAGCATGGTGTGTGATTATG
AGGGGAGGGTTATTTGTGATGGTGGGGTGTTTGAAGGGGGATGCTCGGGCGAGGTAGATGTGGATGGGGTGCGGGAGATG
AGGAGGGAGTGGGGGATGAGGGTGTAA

Upstream 100 bases:

>100_bases
ACAAAGGAAAAAGTCGACAAAGTTAAAGGAAAGGTCTTTCAAAATAAGAAGGAGTGATTCCATCCAAATCTTTTTTTCCG
GACACGCTTTAATAGTTAAT

Downstream 100 bases:

>100_bases
AAATCACATATCTCCATTACAAACTGGTGTATCCGTAGCATAGAGATGCTTTGTTGTTTCAATCAGCGATAGTATTGGTT
TTGCTTCGTCTGGGAAATCT

Product: UDP-glucose pyrophosphorylase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MRVCCAQLIQVWDDVDAAFAKADVFLKEYSGTADIVVFSEQFATGWRPAPAPVSAEDVKCRWLALAAKHNVCVVGSYQKV
EAGGLPQNTMLVCGPSGEVIAEYSKMYLFVPGKEDRCFSPGARPVTFEYGGVKFGCAICFDLRFPELFRAYLKLGCECVL
VQAAWPAARVADWELLLRARALENRGFVFGAACMGYDPASGTDYCGRSMVCDYEGRVICDGGVFEGGCSGEVDVDGVREM
RREWGMRV

Sequences:

>Translated_248_residues
MRVCCAQLIQVWDDVDAAFAKADVFLKEYSGTADIVVFSEQFATGWRPAPAPVSAEDVKCRWLALAAKHNVCVVGSYQKV
EAGGLPQNTMLVCGPSGEVIAEYSKMYLFVPGKEDRCFSPGARPVTFEYGGVKFGCAICFDLRFPELFRAYLKLGCECVL
VQAAWPAARVADWELLLRARALENRGFVFGAACMGYDPASGTDYCGRSMVCDYEGRVICDGGVFEGGCSGEVDVDGVREM
RREWGMRV
>Mature_248_residues
MRVCCAQLIQVWDDVDAAFAKADVFLKEYSGTADIVVFSEQFATGWRPAPAPVSAEDVKCRWLALAAKHNVCVVGSYQKV
EAGGLPQNTMLVCGPSGEVIAEYSKMYLFVPGKEDRCFSPGARPVTFEYGGVKFGCAICFDLRFPELFRAYLKLGCECVL
VQAAWPAARVADWELLLRARALENRGFVFGAACMGYDPASGTDYCGRSMVCDYEGRVICDGGVFEGGCSGEVDVDGVREM
RREWGMRV

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=256, Percent_Identity=30.46875, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI297632350, Length=167, Percent_Identity=34.7305389221557, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI5031947, Length=167, Percent_Identity=34.7305389221557, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI297632348, Length=167, Percent_Identity=34.7305389221557, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1786412, Length=247, Percent_Identity=29.9595141700405, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17556280, Length=204, Percent_Identity=34.3137254901961, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323383, Length=270, Percent_Identity=25.1851851851852, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21355835, Length=195, Percent_Identity=31.7948717948718, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17933642, Length=164, Percent_Identity=32.3170731707317, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 27178; Mature: 27178

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50263 CN_HYDROLASE ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVCCAQLIQVWDDVDAAFAKADVFLKEYSGTADIVVFSEQFATGWRPAPAPVSAEDVKC
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCEE
RWLALAAKHNVCVVGSYQKVEAGGLPQNTMLVCGPSGEVIAEYSKMYLFVPGKEDRCFSP
EEEEEECCCCEEEEECCEEECCCCCCCCCEEEECCCCCCEEEECEEEEEECCCCCCCCCC
GARPVTFEYGGVKFGCAICFDLRFPELFRAYLKLGCECVLVQAAWPAARVADWELLLRAR
CCCEEEEECCCEEEEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHH
ALENRGFVFGAACMGYDPASGTDYCGRSMVCDYEGRVICDGGVFEGGCSGEVDVDGVREM
HHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCHHHHHHH
RREWGMRV
HHHCCCCC
>Mature Secondary Structure
MRVCCAQLIQVWDDVDAAFAKADVFLKEYSGTADIVVFSEQFATGWRPAPAPVSAEDVKC
CCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCEE
RWLALAAKHNVCVVGSYQKVEAGGLPQNTMLVCGPSGEVIAEYSKMYLFVPGKEDRCFSP
EEEEEECCCCEEEEECCEEECCCCCCCCCEEEECCCCCCEEEECEEEEEECCCCCCCCCC
GARPVTFEYGGVKFGCAICFDLRFPELFRAYLKLGCECVLVQAAWPAARVADWELLLRAR
CCCEEEEECCCEEEEEEEEEECCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHH
ALENRGFVFGAACMGYDPASGTDYCGRSMVCDYEGRVICDGGVFEGGCSGEVDVDGVREM
HHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCCCCCCCCHHHHHHH
RREWGMRV
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]