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The map label for this gene is rnc [H]

Identifier: 124486133

GI number: 124486133

Start: 1339909

End: 1340346

Strand: Reverse

Name: rnc [H]

Synonym: Mlab_1315

Alternate gene names: 124486133

Gene position: 1340346-1339909 (Counterclockwise)

Preceding gene: 124486134

Following gene: 124486132

Centisome position: 74.26

GC content: 53.88

Gene sequence:

>438_bases
ATGAACTACTCTGACCTGTATGCAAAGATCGGCTACACGTTTGCGAATGTCGATCTTCTTCTCCATGCCCTCACCCGAAC
GGCCTATGCCCGGGAAAACGAACTTTCCATGAGCGAGACGATGGATTCGCTGGCCGTTCTCGGAGATGCCGTCCTCGATC
TGATCGTGATCCGCCGGTTAATCGAGGAAGGCGAGTTTGATAAAGGCGAGATCACCCGGAAAAAAATCGATCTCGTGAAC
ATGACCGTGGTTCGAAAACTCGCAGAGGATATCGGTCTTCCTGAGTATATGCGGTGGGGAAAAGGCGAACTCCGCATGCA
GATCTGGACAAGCGGCCGAGTTTCAGCCGAATGCTTCGAGGCGTTGATGGGGGCAGCATATCTTGACGGGGGTGTCGAGG
CCTCTTCTGCTATCCTCGATCACGTCTGGATGCCGTGA

Upstream 100 bases:

>100_bases
GCGAAACCAGTATGGGGATGGATCTGACCGGTGTATTAACGATGGAGATGGAGGGTTTTACCTACCTGATCCAGCTCATC
AATCAATACGGGAGAACAGA

Downstream 100 bases:

>100_bases
AAAACCATAGAGCTTATTGGCAGTGAATACGATATGATAGACGTATGGTACGGGTAAAAGCATCCCACATTTTAGTAAAG
ACCGAAGCTCAAGCAAAAGA

Product: hypothetical protein

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MNYSDLYAKIGYTFANVDLLLHALTRTAYARENELSMSETMDSLAVLGDAVLDLIVIRRLIEEGEFDKGEITRKKIDLVN
MTVVRKLAEDIGLPEYMRWGKGELRMQIWTSGRVSAECFEALMGAAYLDGGVEASSAILDHVWMP

Sequences:

>Translated_145_residues
MNYSDLYAKIGYTFANVDLLLHALTRTAYARENELSMSETMDSLAVLGDAVLDLIVIRRLIEEGEFDKGEITRKKIDLVN
MTVVRKLAEDIGLPEYMRWGKGELRMQIWTSGRVSAECFEALMGAAYLDGGVEASSAILDHVWMP
>Mature_145_residues
MNYSDLYAKIGYTFANVDLLLHALTRTAYARENELSMSETMDSLAVLGDAVLDLIVIRRLIEEGEFDKGEITRKKIDLVN
MTVVRKLAEDIGLPEYMRWGKGELRMQIWTSGRVSAECFEALMGAAYLDGGVEASSAILDHVWMP

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Escherichia coli, GI1788920, Length=136, Percent_Identity=30.8823529411765, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 16281; Mature: 16281

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYSDLYAKIGYTFANVDLLLHALTRTAYARENELSMSETMDSLAVLGDAVLDLIVIRRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEEGEFDKGEITRKKIDLVNMTVVRKLAEDIGLPEYMRWGKGELRMQIWTSGRVSAECFE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCHHHHH
ALMGAAYLDGGVEASSAILDHVWMP
HHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNYSDLYAKIGYTFANVDLLLHALTRTAYARENELSMSETMDSLAVLGDAVLDLIVIRRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IEEGEFDKGEITRKKIDLVNMTVVRKLAEDIGLPEYMRWGKGELRMQIWTSGRVSAECFE
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCHHHHH
ALMGAAYLDGGVEASSAILDHVWMP
HHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA