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The map label for this gene is ymdB [C]

Identifier: 124485793

GI number: 124485793

Start: 965356

End: 965907

Strand: Reverse

Name: ymdB [C]

Synonym: Mlab_0972

Alternate gene names: 124485793

Gene position: 965907-965356 (Counterclockwise)

Preceding gene: 124485794

Following gene: 124485785

Centisome position: 53.51

GC content: 57.79

Gene sequence:

>552_bases
ATGGAAGATCCCGTCTTATGGATAACCGACCATCTCGGCGTCGTCAAAACCGACATAACAACCCTCTCCGTCGACGTAAT
CGTCAATGCCGCAAACACCACGCTTCTTGGTGGCGGGGGCGTGGACGGGGCGATTCATCATGCGGCCGGTCCCGGACTTC
TTGCTGAGTGCCGGACGCTTGGGGGGTGCAGGATCGGGGAAGCGAAAATCACGAAAGGCTATGCTCTCCCCGCGAAATAC
ATCATCCACACGGTTGGCCCCGTCTGGTGGGGCGGGAATGAAGGAGAGCCGGAACAACTGAGGGCCTGTTATTTTCATTC
GCTCACGCTTGCCGGGGAACACGGTCTTCGAACCATCGCCTTTCCCGCCGTAAGCACCGGAGTATACGGCTATCCGAAAG
ACAAAGCCGCCGTCATCGCGGTCGAAACGGTTCTGTCGTTTCTCCGGGACGATCCGGATGCATTCGACCGGGTCATTCTG
GTCGCCCACTCCAATGCTGACTTCCAAAATCTCACGGCTGCGGGGAAAATGGTTCGAATCGGTACGACGTGA

Upstream 100 bases:

>100_bases
GCATGGAAGGTGTTTTCGAGGCGGGTTTTTTTGGGTGTGTGGTCACCCGTTTCGTTCCCACAGGAAAAACACTATCCGGC
TGAACGGCGAAGAATTGAGC

Downstream 100 bases:

>100_bases
TGTCGTCCCCATCTCAATTATAGTGTATCTTCCTTTTCCTTTTTCCAAGGCAGTTTCTTATGACTGAACATCTCGCCGAA
CATTGCCCCGCCGAGAATCA

Product: tryptophan--tRNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MEDPVLWITDHLGVVKTDITTLSVDVIVNAANTTLLGGGGVDGAIHHAAGPGLLAECRTLGGCRIGEAKITKGYALPAKY
IIHTVGPVWWGGNEGEPEQLRACYFHSLTLAGEHGLRTIAFPAVSTGVYGYPKDKAAVIAVETVLSFLRDDPDAFDRVIL
VAHSNADFQNLTAAGKMVRIGTT

Sequences:

>Translated_183_residues
MEDPVLWITDHLGVVKTDITTLSVDVIVNAANTTLLGGGGVDGAIHHAAGPGLLAECRTLGGCRIGEAKITKGYALPAKY
IIHTVGPVWWGGNEGEPEQLRACYFHSLTLAGEHGLRTIAFPAVSTGVYGYPKDKAAVIAVETVLSFLRDDPDAFDRVIL
VAHSNADFQNLTAAGKMVRIGTT
>Mature_183_residues
MEDPVLWITDHLGVVKTDITTLSVDVIVNAANTTLLGGGGVDGAIHHAAGPGLLAECRTLGGCRIGEAKITKGYALPAKY
IIHTVGPVWWGGNEGEPEQLRACYFHSLTLAGEHGLRTIAFPAVSTGVYGYPKDKAAVIAVETVLSFLRDDPDAFDRVIL
VAHSNADFQNLTAAGKMVRIGTT

Specific function: Unknown

COG id: COG2110

COG function: function code R; Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Macro domain [H]

Homologues:

Organism=Homo sapiens, GI117968621, Length=163, Percent_Identity=53.3742331288344, Blast_Score=176, Evalue=1e-44,
Organism=Homo sapiens, GI13569840, Length=161, Percent_Identity=52.1739130434783, Blast_Score=175, Evalue=2e-44,
Organism=Homo sapiens, GI207450721, Length=161, Percent_Identity=36.6459627329193, Blast_Score=103, Evalue=9e-23,
Organism=Homo sapiens, GI8923143, Length=161, Percent_Identity=36.6459627329193, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI154813199, Length=147, Percent_Identity=38.7755102040816, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI226371718, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI226371716, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI226371714, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI226371712, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI226371710, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI226371706, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI20336746, Length=147, Percent_Identity=31.9727891156463, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1787283, Length=139, Percent_Identity=56.1151079136691, Blast_Score=149, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17538214, Length=156, Percent_Identity=50.6410256410256, Blast_Score=133, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24586353, Length=133, Percent_Identity=39.0977443609023, Blast_Score=90, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002589
- InterPro:   IPR022942 [H]

Pfam domain/function: PF01661 Macro [H]

EC number: NA

Molecular weight: Translated: 19321; Mature: 19321

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS51154 MACRO

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDPVLWITDHLGVVKTDITTLSVDVIVNAANTTLLGGGGVDGAIHHAAGPGLLAECRTL
CCCCEEEEECCCCEEEECCEEEEEEEEEEECCEEEEECCCCCCEEECCCCCCHHHHHHHC
GGCRIGEAKITKGYALPAKYIIHTVGPVWWGGNEGEPEQLRACYFHSLTLAGEHGLRTIA
CCCEECCCEECCCCCCCHHHHHHHCCCEEECCCCCCHHHHHHHHHHEEEEECCCCCEEEE
FPAVSTGVYGYPKDKAAVIAVETVLSFLRDDPDAFDRVILVAHSNADFQNLTAAGKMVRI
ECCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHCCCCEEEE
GTT
CCC
>Mature Secondary Structure
MEDPVLWITDHLGVVKTDITTLSVDVIVNAANTTLLGGGGVDGAIHHAAGPGLLAECRTL
CCCCEEEEECCCCEEEECCEEEEEEEEEEECCEEEEECCCCCCEEECCCCCCHHHHHHHC
GGCRIGEAKITKGYALPAKYIIHTVGPVWWGGNEGEPEQLRACYFHSLTLAGEHGLRTIA
CCCEECCCEECCCCCCCHHHHHHHCCCEEECCCCCCHHHHHHHHHHEEEEECCCCCEEEE
FPAVSTGVYGYPKDKAAVIAVETVLSFLRDDPDAFDRVILVAHSNADFQNLTAAGKMVRI
ECCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHCCCCEEEE
GTT
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]