BacMap

Definition	Methanocorpusculum labreanum Z chromosome, complete genome.
Accession	NC_008942
Length	1,804,962

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The map label for this gene is dnaJ [H]

Identifier: 124485763

GI number: 124485763

Start: 939957

End: 941090

Strand: Reverse

Name: dnaJ [H]

Synonym: Mlab_0942

Alternate gene names: 124485763

Gene position: 941090-939957 (Counterclockwise)

Preceding gene: 124485764

Following gene: 124485762

Centisome position: 52.14

GC content: 53.97

Gene sequence:

>1134_bases
ATGGGTTCGGAATCGTACTATGATGTCTTAGGTTTGCCCCGTAATGCTACGGAGACAGACATTAAAAAAGCTTACCGAAA
CCTCGCCAAGAAGTATCACCCGGATGTCTGCAAGGATCCCGGGGCTGAGGAGAAGTTCAAGTCGATCAACGAGGCCTACG
ACGTTCTTTCTGATGAGACGAAACGCCGGCAGTATGATCAGCTCGGACATGATAATTTCACGAATGCATCGAAAGGGAAC
TATTCCGGTGCAGGAGGTGCAGGATTCAATGCGGACTTCTCGGGATTCGGAGACATCTTCGATTTCTTCGGCGGAGGGGG
ACGCAGACAGAGCGGGCCGCGCGAAGGCGACGATATGCTGATGCGTATCCAGATCACGCTCGAAGAGGCAGTGTTTGGAA
CGCAAAAAGAGATCGAAGTCATGCATACGGAGAGCTGTCCGGACTGCGATGGTACCGGCAGTGCAACGAAAAAGACCACC
ACATGCAGCAAATGCGGCGGCACTGGTCAGATCAAACAGGTGAAAAATTCCATCTTTGGTCAGATGGTCACCCAGTCGAC
CTGTCCGACCTGCGGCGGCAGAGGAAAAATTCCCGAGACGCCGTGTAAGAAATGCAACGGAACGGGACGAACCAAAGTCC
GCCGTCAGGTGACGGTGAATGTTCCGGCAGGCATCGACAGCGGCATGCGTCTGCGCATGGAAGGATACGGCGAGGCAGGA
GATTACGGAGCGAGAAACGGCGATCTGTACATCGAAGTCTATGTCGTGGCAAATCCGAAGTTCGACCGCGAGGACGACAA
TCTGATCACGCAGTACGAGATTTCCCCGGCACAGGCGGTTCTCGGATGCGAGGTGGAGATCGAGACGATCGACAGAAAGA
AGGTCATGCTCAAGGTCCCGGCAGGAATCGCCTACGGGACCCGTCTCAGGATCGCCGGCGAAGGTGTTCGAAGACGCGGC
AACTATGGAAATCTGCTGGTCAGAATCGTGATCGCCACGCCAAAGAAGGTCTCTTCGGCTGAAAGAGAGCTGTATGAAAA
GCTTCTCAAGGCCGAAGGAAATGCCGGTTCTTCCTCATCTTCCAAGGATGATGAGAAGGAAGGCCGCAGCAAAAAGCGCG
GGATCTTTAAGTAA

Upstream 100 bases:

>100_bases
GTGAAGGCAACTGTGACTCCTGCAAAACCGACGACAATGTCGTAGACGCAGACTACGAAGTCAAAAAGGACTAAACCTCC
TTTTTTTGGGAATGTAGAAA

Downstream 100 bases:

>100_bases
GCGAGGGTTGAGTGAAGGTCCCCTTCACTCCACCCGAAGCGGGGAGCAAATCTTTGATTTGCGACCAAGTGAGGATGGAT
CTTCACACAGCCCCGAGAAG

Product: putative CoA-substrate-specific enzyme activase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MGSESYYDVLGLPRNATETDIKKAYRNLAKKYHPDVCKDPGAEEKFKSINEAYDVLSDETKRRQYDQLGHDNFTNASKGN
YSGAGGAGFNADFSGFGDIFDFFGGGGRRQSGPREGDDMLMRIQITLEEAVFGTQKEIEVMHTESCPDCDGTGSATKKTT
TCSKCGGTGQIKQVKNSIFGQMVTQSTCPTCGGRGKIPETPCKKCNGTGRTKVRRQVTVNVPAGIDSGMRLRMEGYGEAG
DYGARNGDLYIEVYVVANPKFDREDDNLITQYEISPAQAVLGCEVEIETIDRKKVMLKVPAGIAYGTRLRIAGEGVRRRG
NYGNLLVRIVIATPKKVSSAERELYEKLLKAEGNAGSSSSSKDDEKEGRSKKRGIFK

Sequences:

>Translated_377_residues
MGSESYYDVLGLPRNATETDIKKAYRNLAKKYHPDVCKDPGAEEKFKSINEAYDVLSDETKRRQYDQLGHDNFTNASKGN
YSGAGGAGFNADFSGFGDIFDFFGGGGRRQSGPREGDDMLMRIQITLEEAVFGTQKEIEVMHTESCPDCDGTGSATKKTT
TCSKCGGTGQIKQVKNSIFGQMVTQSTCPTCGGRGKIPETPCKKCNGTGRTKVRRQVTVNVPAGIDSGMRLRMEGYGEAG
DYGARNGDLYIEVYVVANPKFDREDDNLITQYEISPAQAVLGCEVEIETIDRKKVMLKVPAGIAYGTRLRIAGEGVRRRG
NYGNLLVRIVIATPKKVSSAERELYEKLLKAEGNAGSSSSSKDDEKEGRSKKRGIFK
>Mature_376_residues
GSESYYDVLGLPRNATETDIKKAYRNLAKKYHPDVCKDPGAEEKFKSINEAYDVLSDETKRRQYDQLGHDNFTNASKGNY
SGAGGAGFNADFSGFGDIFDFFGGGGRRQSGPREGDDMLMRIQITLEEAVFGTQKEIEVMHTESCPDCDGTGSATKKTTT
CSKCGGTGQIKQVKNSIFGQMVTQSTCPTCGGRGKIPETPCKKCNGTGRTKVRRQVTVNVPAGIDSGMRLRMEGYGEAGD
YGARNGDLYIEVYVVANPKFDREDDNLITQYEISPAQAVLGCEVEIETIDRKKVMLKVPAGIAYGTRLRIAGEGVRRRGN
YGNLLVRIVIATPKKVSSAERELYEKLLKAEGNAGSSSSSKDDEKEGRSKKRGIFK

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI205360838, Length=351, Percent_Identity=35.3276353276353, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI205360840, Length=351, Percent_Identity=35.3276353276353, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4504511, Length=357, Percent_Identity=31.9327731092437, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI194328758, Length=342, Percent_Identity=30.7017543859649, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI194328760, Length=342, Percent_Identity=30.7017543859649, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI5031741, Length=348, Percent_Identity=30.1724137931034, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI7706495, Length=365, Percent_Identity=29.5890410958904, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI6631085, Length=368, Percent_Identity=29.0760869565217, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI194328762, Length=305, Percent_Identity=27.2131147540984, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI9558755, Length=112, Percent_Identity=47.3214285714286, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI194306642, Length=102, Percent_Identity=50.9803921568627, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI194306640, Length=102, Percent_Identity=50.9803921568627, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5453690, Length=367, Percent_Identity=26.9754768392371, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI201862518, Length=118, Percent_Identity=45.7627118644068, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI201862587, Length=118, Percent_Identity=45.7627118644068, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI56549115, Length=118, Percent_Identity=45.7627118644068, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI27151736, Length=108, Percent_Identity=45.3703703703704, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI88501736, Length=108, Percent_Identity=45.3703703703704, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI56687498, Length=63, Percent_Identity=58.7301587301587, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI72534740, Length=108, Percent_Identity=43.5185185185185, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI39204547, Length=176, Percent_Identity=33.5227272727273, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI45504382, Length=67, Percent_Identity=59.7014925373134, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI22749377, Length=102, Percent_Identity=39.2156862745098, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI23503241, Length=108, Percent_Identity=44.4444444444444, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI17388799, Length=105, Percent_Identity=45.7142857142857, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4885495, Length=66, Percent_Identity=57.5757575757576, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI47777312, Length=105, Percent_Identity=42.8571428571429, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI29126218, Length=67, Percent_Identity=50.7462686567164, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI21553335, Length=68, Percent_Identity=54.4117647058823, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI68077168, Length=63, Percent_Identity=53.968253968254, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI68077166, Length=63, Percent_Identity=53.968253968254, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786197, Length=367, Percent_Identity=42.5068119891008, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI1787235, Length=358, Percent_Identity=30.7262569832402, Blast_Score=157, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17553096, Length=358, Percent_Identity=34.6368715083799, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17553098, Length=358, Percent_Identity=34.6368715083799, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17507263, Length=343, Percent_Identity=35.2769679300292, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI212645553, Length=342, Percent_Identity=30.4093567251462, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538236, Length=111, Percent_Identity=44.1441441441441, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17534355, Length=71, Percent_Identity=59.1549295774648, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554644, Length=96, Percent_Identity=46.875, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115532378, Length=97, Percent_Identity=38.1443298969072, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17563890, Length=241, Percent_Identity=25.3112033195021, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17568643, Length=65, Percent_Identity=55.3846153846154, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532476, Length=63, Percent_Identity=47.6190476190476, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=348, Percent_Identity=35.0574712643678, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6323870, Length=368, Percent_Identity=35.3260869565217, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6321094, Length=386, Percent_Identity=31.6062176165803, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323119, Length=404, Percent_Identity=28.7128712871287, Blast_Score=112, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6323813, Length=119, Percent_Identity=43.6974789915966, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320888, Length=104, Percent_Identity=43.2692307692308, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324321, Length=63, Percent_Identity=52.3809523809524, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322194, Length=65, Percent_Identity=47.6923076923077, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45549272, Length=401, Percent_Identity=31.6708229426434, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45552813, Length=376, Percent_Identity=32.1808510638298, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45552811, Length=378, Percent_Identity=32.010582010582, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI20129487, Length=360, Percent_Identity=30, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24584014, Length=360, Percent_Identity=30, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574949, Length=362, Percent_Identity=27.3480662983425, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646562, Length=346, Percent_Identity=28.3236994219653, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646560, Length=346, Percent_Identity=28.3236994219653, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646558, Length=346, Percent_Identity=28.3236994219653, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646556, Length=346, Percent_Identity=28.3236994219653, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21357547, Length=346, Percent_Identity=28.3236994219653, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19920464, Length=349, Percent_Identity=30.3724928366762, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI85726398, Length=367, Percent_Identity=26.9754768392371, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24658562, Length=367, Percent_Identity=27.5204359673025, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24658555, Length=367, Percent_Identity=27.5204359673025, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI18858081, Length=365, Percent_Identity=27.6712328767123, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17737735, Length=69, Percent_Identity=55.0724637681159, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28574723, Length=69, Percent_Identity=55.0724637681159, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24668523, Length=69, Percent_Identity=55.0724637681159, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24654066, Length=70, Percent_Identity=51.4285714285714, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654070, Length=70, Percent_Identity=51.4285714285714, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654068, Length=70, Percent_Identity=51.4285714285714, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24654072, Length=70, Percent_Identity=51.4285714285714, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641698, Length=63, Percent_Identity=49.2063492063492, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641696, Length=63, Percent_Identity=49.2063492063492, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24668492, Length=69, Percent_Identity=49.2753623188406, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21358273, Length=117, Percent_Identity=40.1709401709402, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357687, Length=63, Percent_Identity=55.5555555555556, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161077138, Length=65, Percent_Identity=50.7692307692308, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 41188; Mature: 41057

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSESYYDVLGLPRNATETDIKKAYRNLAKKYHPDVCKDPGAEEKFKSINEAYDVLSDET
CCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHH
KRRQYDQLGHDNFTNASKGNYSGAGGAGFNADFSGFGDIFDFFGGGGRRQSGPREGDDML
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEE
MRIQITLEEAVFGTQKEIEVMHTESCPDCDGTGSATKKTTTCSKCGGTGQIKQVKNSIFG
EEEEEEEHHHHCCCCHHEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHH
QMVTQSTCPTCGGRGKIPETPCKKCNGTGRTKVRRQVTVNVPAGIDSGMRLRMEGYGEAG
HHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEECCCCCC
DYGARNGDLYIEVYVVANPKFDREDDNLITQYEISPAQAVLGCEVEIETIDRKKVMLKVP
CCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCHHHEEEECEEEEEECCCCEEEEEEC
AGIAYGTRLRIAGEGVRRRGNYGNLLVRIVIATPKKVSSAERELYEKLLKAEGNAGSSSS
CCEEECCEEEEECCHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
SKDDEKEGRSKKRGIFK
CCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
GSESYYDVLGLPRNATETDIKKAYRNLAKKYHPDVCKDPGAEEKFKSINEAYDVLSDET
CCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHH
KRRQYDQLGHDNFTNASKGNYSGAGGAGFNADFSGFGDIFDFFGGGGRRQSGPREGDDML
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEE
MRIQITLEEAVFGTQKEIEVMHTESCPDCDGTGSATKKTTTCSKCGGTGQIKQVKNSIFG
EEEEEEEHHHHCCCCHHEEEEECCCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHH
QMVTQSTCPTCGGRGKIPETPCKKCNGTGRTKVRRQVTVNVPAGIDSGMRLRMEGYGEAG
HHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEEECCCCCCCCCEEEEECCCCCC
DYGARNGDLYIEVYVVANPKFDREDDNLITQYEISPAQAVLGCEVEIETIDRKKVMLKVP
CCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCHHHEEEECEEEEEECCCCEEEEEEC
AGIAYGTRLRIAGEGVRRRGNYGNLLVRIVIATPKKVSSAERELYEKLLKAEGNAGSSSS
CCEEECCEEEEECCHHHCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
SKDDEKEGRSKKRGIFK
CCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]