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The map label for this gene is 124485035

Identifier: 124485035

GI number: 124485035

Start: 199277

End: 200440

Strand: Reverse

Name: 124485035

Synonym: Mlab_0208

Alternate gene names: NA

Gene position: 200440-199277 (Counterclockwise)

Preceding gene: 124485037

Following gene: 124485034

Centisome position: 11.1

GC content: 52.41

Gene sequence:

>1164_bases
ATGTTTATTCTCATATATGTAACAGACTTTCCCATGTATAAAGAAACACTGCTCATGATGCCGGGACCCGTTCCGATGCC
CGAAACGGTCCGGAATGCAATGACGAAACAGGCAATCAACCACCGGAGTACGGAGTTTGGCGACTGCTATGCAGATATTG
TCAGAGGCTTAAAACCCATCTTCGGCACGACAAACGATATGCTTGTCCTCTCCGGCTCGGGAACTGCTGGTCAGGAAGCT
GCGATCGGCTCGTTTGCCAAAGGCAAAAAAATCGTATCCCTCGTGAATGGAAAGTTCGGAGAAAGACTCGGCCTGATCTC
CAAGATCTACGGCGAGACCACGATGATCGAATCAGAGTGGGGACATGCGCTGAATCTCGAAGCCCTCAAACAGGAACTGG
AAAACGGCGCAGAAGTCGTAACTCTCGTCCACAACGAAACCTCTGCAGCAATCCTGAATCCAGCCGAAGAGGTTGGAAAA
CTAGCACGAAAATACGATGCACTGTTCATCCTCGATGCGATCACTTCGATCGGCGGAGACGTCGTTAAGGCAGATGCCTG
GGGCGCTGATGTAACGATCGTCGGAAGCCAGAAATGTCTGGCAGCCCCTGCAGGACTTGCCGCCGTTTCCGTTTCACAGA
GAGCCTGGGACAGACTCTCCGAGAACAGACCGTTCTATCTCGACTTAAAGAAGGCAAAGAAATCAGCCGACGGCAACCCG
ATGGAAACTCCGGCAACACCGGCCGTTCCGTTGTTCCTCGCACTGCGCGAAGCATGCAGACTCATCGAAGAAGAGGGGCT
TGAAAACAGGATCGCACGCCACCACAGAATGTCCGGCGCCGTTCGCGCAGCCGGCGAAGCATGGGGTCTTTCGCTTGTAC
CTCAGGTCGATGCTCTGCAAAAAGCATCGAACACCGTCACCGGATTCTTCTATCCGGAAGGCGTCGAAGATGCAAAAATC
CGTGGAGCCTGCAAAAAGATGGGAATCGAGTTTGCCGGCGGGCAGGATCGGTTCAAAGGAAAGATCTTCAGAATCGGAAA
TATGGGTATTATCGATACGCCCGAGATCATCGCAACCATTGCAGCTGTTCAGATGTGCTTCAAGAAAGCCGGCTACAATC
TCGAAGGCGACGGACTTTCCGCAGCAGTCGATTTCTTATCCTAA

Upstream 100 bases:

>100_bases
AACGGCCGTTGCCTTATCAACGATCGCCTGGTCCGAAACCGAACCTGCTATAACTGCGACTTCTGGCATCTGATACAACC
TCTATGGAATTACTATATGT

Downstream 100 bases:

>100_bases
TCTCTTTTTTTCAGACCAACGTCTTTCCTTAAATATCTTGCAGAACAGACATAGATAGTATGTTGCCTCTTTCAGAAAAC
ATCGCTGCAGTCCCTCCGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MFILIYVTDFPMYKETLLMMPGPVPMPETVRNAMTKQAINHRSTEFGDCYADIVRGLKPIFGTTNDMLVLSGSGTAGQEA
AIGSFAKGKKIVSLVNGKFGERLGLISKIYGETTMIESEWGHALNLEALKQELENGAEVVTLVHNETSAAILNPAEEVGK
LARKYDALFILDAITSIGGDVVKADAWGADVTIVGSQKCLAAPAGLAAVSVSQRAWDRLSENRPFYLDLKKAKKSADGNP
METPATPAVPLFLALREACRLIEEEGLENRIARHHRMSGAVRAAGEAWGLSLVPQVDALQKASNTVTGFFYPEGVEDAKI
RGACKKMGIEFAGGQDRFKGKIFRIGNMGIIDTPEIIATIAAVQMCFKKAGYNLEGDGLSAAVDFLS

Sequences:

>Translated_387_residues
MFILIYVTDFPMYKETLLMMPGPVPMPETVRNAMTKQAINHRSTEFGDCYADIVRGLKPIFGTTNDMLVLSGSGTAGQEA
AIGSFAKGKKIVSLVNGKFGERLGLISKIYGETTMIESEWGHALNLEALKQELENGAEVVTLVHNETSAAILNPAEEVGK
LARKYDALFILDAITSIGGDVVKADAWGADVTIVGSQKCLAAPAGLAAVSVSQRAWDRLSENRPFYLDLKKAKKSADGNP
METPATPAVPLFLALREACRLIEEEGLENRIARHHRMSGAVRAAGEAWGLSLVPQVDALQKASNTVTGFFYPEGVEDAKI
RGACKKMGIEFAGGQDRFKGKIFRIGNMGIIDTPEIIATIAAVQMCFKKAGYNLEGDGLSAAVDFLS
>Mature_387_residues
MFILIYVTDFPMYKETLLMMPGPVPMPETVRNAMTKQAINHRSTEFGDCYADIVRGLKPIFGTTNDMLVLSGSGTAGQEA
AIGSFAKGKKIVSLVNGKFGERLGLISKIYGETTMIESEWGHALNLEALKQELENGAEVVTLVHNETSAAILNPAEEVGK
LARKYDALFILDAITSIGGDVVKADAWGADVTIVGSQKCLAAPAGLAAVSVSQRAWDRLSENRPFYLDLKKAKKSADGNP
METPATPAVPLFLALREACRLIEEEGLENRIARHHRMSGAVRAAGEAWGLSLVPQVDALQKASNTVTGFFYPEGVEDAKI
RGACKKMGIEFAGGQDRFKGKIFRIGNMGIIDTPEIIATIAAVQMCFKKAGYNLEGDGLSAAVDFLS

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=370, Percent_Identity=31.0810810810811, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17536281, Length=343, Percent_Identity=29.1545189504373, Blast_Score=131, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6321079, Length=360, Percent_Identity=26.1111111111111, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17530823, Length=366, Percent_Identity=30.327868852459, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 41634; Mature: 41634

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFILIYVTDFPMYKETLLMMPGPVPMPETVRNAMTKQAINHRSTEFGDCYADIVRGLKPI
CEEEEEEECCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FGTTNDMLVLSGSGTAGQEAAIGSFAKGKKIVSLVNGKFGERLGLISKIYGETTMIESEW
HCCCCCEEEEECCCCCCCHHHHCHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCC
GHALNLEALKQELENGAEVVTLVHNETSAAILNPAEEVGKLARKYDALFILDAITSIGGD
CCEECHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VVKADAWGADVTIVGSQKCLAAPAGLAAVSVSQRAWDRLSENRPFYLDLKKAKKSADGNP
EEEECCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCCC
METPATPAVPLFLALREACRLIEEEGLENRIARHHRMSGAVRAAGEAWGLSLVPQVDALQ
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
KASNTVTGFFYPEGVEDAKIRGACKKMGIEFAGGQDRFKGKIFRIGNMGIIDTPEIIATI
HHCCCEEEEECCCCCCCHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCCCCHHHHHHH
AAVQMCFKKAGYNLEGDGLSAAVDFLS
HHHHHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MFILIYVTDFPMYKETLLMMPGPVPMPETVRNAMTKQAINHRSTEFGDCYADIVRGLKPI
CEEEEEEECCCCHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FGTTNDMLVLSGSGTAGQEAAIGSFAKGKKIVSLVNGKFGERLGLISKIYGETTMIESEW
HCCCCCEEEEECCCCCCCHHHHCHHHCCHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCC
GHALNLEALKQELENGAEVVTLVHNETSAAILNPAEEVGKLARKYDALFILDAITSIGGD
CCEECHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
VVKADAWGADVTIVGSQKCLAAPAGLAAVSVSQRAWDRLSENRPFYLDLKKAKKSADGNP
EEEECCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCCC
METPATPAVPLFLALREACRLIEEEGLENRIARHHRMSGAVRAAGEAWGLSLVPQVDALQ
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
KASNTVTGFFYPEGVEDAKIRGACKKMGIEFAGGQDRFKGKIFRIGNMGIIDTPEIIATI
HHCCCEEEEECCCCCCCHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCCCCHHHHHHH
AAVQMCFKKAGYNLEGDGLSAAVDFLS
HHHHHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]