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The map label for this gene is aspC [H]

Identifier: 124485034

GI number: 124485034

Start: 198087

End: 199217

Strand: Reverse

Name: aspC [H]

Synonym: Mlab_0207

Alternate gene names: 124485034

Gene position: 199217-198087 (Counterclockwise)

Preceding gene: 124485035

Following gene: 124485033

Centisome position: 11.04

GC content: 51.11

Gene sequence:

>1131_bases
ATGTTGCCTCTTTCAGAAAACATCGCTGCAGTCCCTCCGTCTGCAACGATGGCGATGAACAACCGTTCAAAGGATATGGT
CGCCAAAGGGATTGATGTGATCAGCCTCGCCGTCGGTGAACCGGACTTCGCTACGCCCTCTCATATTACTCAGGCTGCAA
TAGATGCCCTGCACCGTGGCGAGACTCATTATGCACCGTCCCGTGGCATCCCTGCCCTGACCAAAGCGATCGCCGATAAA
CTCAATACGGAAAACCATATCCCGACACATCAGAACAGAATCCTCTGTACAAGCGGAGCCAAGGATGCCATTCGGATCAC
AATGATGGCATGCCTAAATCCCGGCGATGAAGTGATTATTCTTGATCCGGCGTGGGTCTCATACGACCCTTGCGTCACTA
TTGCACGAGGAAAAGCAGTTCATCATTCTCTCAACGAAAATTTCCAGGTCGATGAGTCCCTATACGAAAAAATCACTGAT
AAGACCAAGATGATCATCGTGAACACGCCATCGAACCCCACCGGTTCGATCCTCGGCCGTTCATCGCTCAGGATCCTTGC
GGATGCCTGCATCGATCACGACCTGTATTGTCTTTCAGACGAGATCTACGAAAAACTCGTCTATGGTCAGGAGCATGTGT
CGATGGGATCCCTGCCGGATATGGATGAACGCACGATCACCATCAACGGATTTTCCAAAGCCTACGCGATGACCGGATGG
AGACTTGGCTATATCTCGGCTCCGGAAAACGTTATCCCGTACATGGATAAAGTCATGCAGCACTCGGTTGGAAACGTCAA
CACCTTTGCTATGTGGGGAGGCGTTGCTGCCCTCACAGGTGACCAGACCTGTGTCGAATCGATGCGAAAAGAGTTCGAGA
TACGGAAAAAATATGTCATCGGCAGACTTGCCGGCATGGGACTGAAAACTGCACCGGCAAACGGTGCATTCTATGCATTC
ATCAACTGCGGAGGCGATGATGGGGCAACAGCAAATCTTTGGCTTGACAAAGCTCATGTGGCGGCAACCCCGGGATTTGC
GTTTGGAGCTCCAGGATGGATTCGGATCTCCTACGCAGCATCCCTCGAAAGACTGGAAGAAGCACTCAACAGAATAGAAG
CTGTTCTCTAA

Upstream 100 bases:

>100_bases
AAGGCGACGGACTTTCCGCAGCAGTCGATTTCTTATCCTAATCTCTTTTTTTCAGACCAACGTCTTTCCTTAAATATCTT
GCAGAACAGACATAGATAGT

Downstream 100 bases:

>100_bases
TATAAGAGAAACCATACCTGCCTTCTTTTTTTCTTCGGCGCGTATCGGGTATCCTCCATTACGTCGTGGGGATACGCCCC
GGAAACATCGCAGATGACCG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MLPLSENIAAVPPSATMAMNNRSKDMVAKGIDVISLAVGEPDFATPSHITQAAIDALHRGETHYAPSRGIPALTKAIADK
LNTENHIPTHQNRILCTSGAKDAIRITMMACLNPGDEVIILDPAWVSYDPCVTIARGKAVHHSLNENFQVDESLYEKITD
KTKMIIVNTPSNPTGSILGRSSLRILADACIDHDLYCLSDEIYEKLVYGQEHVSMGSLPDMDERTITINGFSKAYAMTGW
RLGYISAPENVIPYMDKVMQHSVGNVNTFAMWGGVAALTGDQTCVESMRKEFEIRKKYVIGRLAGMGLKTAPANGAFYAF
INCGGDDGATANLWLDKAHVAATPGFAFGAPGWIRISYAASLERLEEALNRIEAVL

Sequences:

>Translated_376_residues
MLPLSENIAAVPPSATMAMNNRSKDMVAKGIDVISLAVGEPDFATPSHITQAAIDALHRGETHYAPSRGIPALTKAIADK
LNTENHIPTHQNRILCTSGAKDAIRITMMACLNPGDEVIILDPAWVSYDPCVTIARGKAVHHSLNENFQVDESLYEKITD
KTKMIIVNTPSNPTGSILGRSSLRILADACIDHDLYCLSDEIYEKLVYGQEHVSMGSLPDMDERTITINGFSKAYAMTGW
RLGYISAPENVIPYMDKVMQHSVGNVNTFAMWGGVAALTGDQTCVESMRKEFEIRKKYVIGRLAGMGLKTAPANGAFYAF
INCGGDDGATANLWLDKAHVAATPGFAFGAPGWIRISYAASLERLEEALNRIEAVL
>Mature_376_residues
MLPLSENIAAVPPSATMAMNNRSKDMVAKGIDVISLAVGEPDFATPSHITQAAIDALHRGETHYAPSRGIPALTKAIADK
LNTENHIPTHQNRILCTSGAKDAIRITMMACLNPGDEVIILDPAWVSYDPCVTIARGKAVHHSLNENFQVDESLYEKITD
KTKMIIVNTPSNPTGSILGRSSLRILADACIDHDLYCLSDEIYEKLVYGQEHVSMGSLPDMDERTITINGFSKAYAMTGW
RLGYISAPENVIPYMDKVMQHSVGNVNTFAMWGGVAALTGDQTCVESMRKEFEIRKKYVIGRLAGMGLKTAPANGAFYAF
INCGGDDGATANLWLDKAHVAATPGFAFGAPGWIRISYAASLERLEEALNRIEAVL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=314, Percent_Identity=32.484076433121, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI56713256, Length=314, Percent_Identity=32.484076433121, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI95147551, Length=313, Percent_Identity=30.6709265175719, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI169881279, Length=313, Percent_Identity=30.6709265175719, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI169881281, Length=222, Percent_Identity=30.6306306306306, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI4507369, Length=224, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=27.9778393351801, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788722, Length=364, Percent_Identity=25.8241758241758, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788627, Length=231, Percent_Identity=31.1688311688312, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787909, Length=365, Percent_Identity=21.3698630136986, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17567369, Length=245, Percent_Identity=34.2857142857143, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=261, Percent_Identity=31.4176245210728, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=261, Percent_Identity=31.4176245210728, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=369, Percent_Identity=26.0162601626016, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=321, Percent_Identity=26.791277258567, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28573069, Length=314, Percent_Identity=31.5286624203822, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24646114, Length=314, Percent_Identity=31.5286624203822, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28573067, Length=314, Percent_Identity=31.5286624203822, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28573065, Length=314, Percent_Identity=31.5286624203822, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI18859735, Length=369, Percent_Identity=24.6612466124661, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 40816; Mature: 40816

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLSENIAAVPPSATMAMNNRSKDMVAKGIDVISLAVGEPDFATPSHITQAAIDALHRG
CCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
ETHYAPSRGIPALTKAIADKLNTENHIPTHQNRILCTSGAKDAIRITMMACLNPGDEVII
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHEEEEEECCCCCCCEEE
LDPAWVSYDPCVTIARGKAVHHSLNENFQVDESLYEKITDKTKMIIVNTPSNPTGSILGR
ECCCCCCCCCEEEEECCCHHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCC
SSLRILADACIDHDLYCLSDEIYEKLVYGQEHVSMGSLPDMDERTITINGFSKAYAMTGW
CHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCHHHHCCCE
RLGYISAPENVIPYMDKVMQHSVGNVNTFAMWGGVAALTGDQTCVESMRKEFEIRKKYVI
EEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
GRLAGMGLKTAPANGAFYAFINCGGDDGATANLWLDKAHVAATPGFAFGAPGWIRISYAA
HHHHCCCCEECCCCCCEEEEEEECCCCCCEEEEEEECCCEEECCCCCCCCCCEEEEEHHH
SLERLEEALNRIEAVL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPLSENIAAVPPSATMAMNNRSKDMVAKGIDVISLAVGEPDFATPSHITQAAIDALHRG
CCCCCCCCCCCCCCCEEEECCCCHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
ETHYAPSRGIPALTKAIADKLNTENHIPTHQNRILCTSGAKDAIRITMMACLNPGDEVII
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHEEEEEECCCCCCCEEE
LDPAWVSYDPCVTIARGKAVHHSLNENFQVDESLYEKITDKTKMIIVNTPSNPTGSILGR
ECCCCCCCCCEEEEECCCHHHHHCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCC
SSLRILADACIDHDLYCLSDEIYEKLVYGQEHVSMGSLPDMDERTITINGFSKAYAMTGW
CHHHHHHHHHHCCCEEEHHHHHHHHHHCCHHHCCCCCCCCCCCCEEEEECCCHHHHCCCE
RLGYISAPENVIPYMDKVMQHSVGNVNTFAMWGGVAALTGDQTCVESMRKEFEIRKKYVI
EEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHHH
GRLAGMGLKTAPANGAFYAFINCGGDDGATANLWLDKAHVAATPGFAFGAPGWIRISYAA
HHHHCCCCEECCCCCCEEEEEEECCCCCCEEEEEEECCCEEECCCCCCCCCCEEEEEHHH
SLERLEEALNRIEAVL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]