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The map label for this gene is 124484888

Identifier: 124484888

GI number: 124484888

Start: 59889

End: 61094

Strand: Reverse

Name: 124484888

Synonym: Mlab_0059

Alternate gene names: NA

Gene position: 61094-59889 (Counterclockwise)

Preceding gene: 124484889

Following gene: 124484887

Centisome position: 3.38

GC content: 53.15

Gene sequence:

>1206_bases
ATGGCAAAGCAGATCAAAGACCCGGTCCACGGATACATCGAAGTTCCAACGCCTCTCGTCCCCCTTCTGGATACGGAAGT
CGTTCAGCGGCTCAGATATATCAAACAGCTCGGATTCGTATATCTCGTGTATCCGGGAGCGAACCACACGCGTTTCGAAC
ACTCGCTTGGAGCGATGCATCTCGCTTCTCTGCTTGCAAGGCAGCTCGATCTGAGTAAGGACGATACGCTTCTGGTCTGC
ACGGCCGCCCTTCTCCATGATATTGGACACGGACCGTTCTCCCATGCAAGCGAAAAACTCCGGGCTGAGTACGGGCCGTT
CTCCCATGATGATATCGCACCGCTCCTGATAATGCCGGAGATCTCCGACATTCTGGATGAGAACGGCACGGATCCTCACG
AAATCGCCGGGATCGTTTCAGGACATCACCGGCTCGCCGAGATCATACACGGCGATCTTGACGTTGACCGGATGGATTAT
CTTTTACGCGATGCACACTATACCGGAGTCCCATACGGAAATCTCGATGCCGGCCGGCTTATCCAGTCCCTTGTTTTGAC
GGAAGACGGACTTGCCATCAAAGAATCCGGCATCGCGGCGGCTGAATCACTTTTGATTGCGAGAACGCTCATGGGGCCTT
CCGTCTATTATCATCACGTCGGCAGAATCGCAGAACAGATGTTTCTGCTTGCCGGAAGAAGTCATTTCGCCGACGAAAAA
CCGGATGCATTCATGAGAATGGACGACCTTGCAGGAACAACTCTTCTTATGAACTCGCCATCAAGCGTCTCCAAAGAGAT
GATGCACAGGATATGGAGAAGAGATCTCTACAAGCGGGCGGTCTACACCGGGCGCGAACAACTGGACATGAACCGGCTCT
CGACCCTTAGACCGGAAGAGAAAGACCGGATGAAGCGGGCGATCGCCGAAACAGCAGGTGTCCCCGATGAAAAAATCATC
CTCGACATACCCCCCATCCGAAAAGAGATGCGGATGATGGTCCAGGTACAAAACCAGCACGACCTTGTCGCTTTTGAAGA
AATCATCCCGCTGTTATCCATGATGAATGCAACAAGGCAGGATCAGTGGCGTCTTGGTGTGTTTGCCCCGGCAGATATCC
TTGAAAAGGTCGGCGACGCGGCACGGGAGGTCCTTTCCCTGCGCCGGGCAACAAAACAAGATAAACTCCCAGGTACTATA
GTATAG

Upstream 100 bases:

>100_bases
AGACGGCAGGATCATCAAAGAACATACATCCGTAGTTACATTCAGCGACGGCGGAAAAGATCCGGCCAACCTCAAAAACA
CGCTCACATCATCCTGAGAA

Downstream 100 bases:

>100_bases
ATATGAAGAGGATCGTCGTCGGGGTGACCGGAGCATCCGGGATACTGTATGCAAAACGGTTACTTGAGGCGCTCAAACAG
ACAAAAGCCGAAGTTTTTCT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MAKQIKDPVHGYIEVPTPLVPLLDTEVVQRLRYIKQLGFVYLVYPGANHTRFEHSLGAMHLASLLARQLDLSKDDTLLVC
TAALLHDIGHGPFSHASEKLRAEYGPFSHDDIAPLLIMPEISDILDENGTDPHEIAGIVSGHHRLAEIIHGDLDVDRMDY
LLRDAHYTGVPYGNLDAGRLIQSLVLTEDGLAIKESGIAAAESLLIARTLMGPSVYYHHVGRIAEQMFLLAGRSHFADEK
PDAFMRMDDLAGTTLLMNSPSSVSKEMMHRIWRRDLYKRAVYTGREQLDMNRLSTLRPEEKDRMKRAIAETAGVPDEKII
LDIPPIRKEMRMMVQVQNQHDLVAFEEIIPLLSMMNATRQDQWRLGVFAPADILEKVGDAAREVLSLRRATKQDKLPGTI
V

Sequences:

>Translated_401_residues
MAKQIKDPVHGYIEVPTPLVPLLDTEVVQRLRYIKQLGFVYLVYPGANHTRFEHSLGAMHLASLLARQLDLSKDDTLLVC
TAALLHDIGHGPFSHASEKLRAEYGPFSHDDIAPLLIMPEISDILDENGTDPHEIAGIVSGHHRLAEIIHGDLDVDRMDY
LLRDAHYTGVPYGNLDAGRLIQSLVLTEDGLAIKESGIAAAESLLIARTLMGPSVYYHHVGRIAEQMFLLAGRSHFADEK
PDAFMRMDDLAGTTLLMNSPSSVSKEMMHRIWRRDLYKRAVYTGREQLDMNRLSTLRPEEKDRMKRAIAETAGVPDEKII
LDIPPIRKEMRMMVQVQNQHDLVAFEEIIPLLSMMNATRQDQWRLGVFAPADILEKVGDAAREVLSLRRATKQDKLPGTI
V
>Mature_400_residues
AKQIKDPVHGYIEVPTPLVPLLDTEVVQRLRYIKQLGFVYLVYPGANHTRFEHSLGAMHLASLLARQLDLSKDDTLLVCT
AALLHDIGHGPFSHASEKLRAEYGPFSHDDIAPLLIMPEISDILDENGTDPHEIAGIVSGHHRLAEIIHGDLDVDRMDYL
LRDAHYTGVPYGNLDAGRLIQSLVLTEDGLAIKESGIAAAESLLIARTLMGPSVYYHHVGRIAEQMFLLAGRSHFADEKP
DAFMRMDDLAGTTLLMNSPSSVSKEMMHRIWRRDLYKRAVYTGREQLDMNRLSTLRPEEKDRMKRAIAETAGVPDEKIIL
DIPPIRKEMRMMVQVQNQHDLVAFEEIIPLLSMMNATRQDQWRLGVFAPADILEKVGDAAREVLSLRRATKQDKLPGTIV

Specific function: Unknown

COG id: COG1078

COG function: function code R; HD superfamily phosphohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Homo sapiens, GI38016914, Length=299, Percent_Identity=33.4448160535117, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17537829, Length=226, Percent_Identity=34.070796460177, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17537827, Length=226, Percent_Identity=34.070796460177, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24666702, Length=192, Percent_Identity=30.7291666666667, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221512937, Length=192, Percent_Identity=30.7291666666667, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003607
- InterPro:   IPR006675
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45069; Mature: 44938

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQIKDPVHGYIEVPTPLVPLLDTEVVQRLRYIKQLGFVYLVYPGANHTRFEHSLGAMH
CCCCCCCCCCCEEECCCCCHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
LASLLARQLDLSKDDTLLVCTAALLHDIGHGPFSHASEKLRAEYGPFSHDDIAPLLIMPE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCC
ISDILDENGTDPHEIAGIVSGHHRLAEIIHGDLDVDRMDYLLRDAHYTGVPYGNLDAGRL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHH
IQSLVLTEDGLAIKESGIAAAESLLIARTLMGPSVYYHHVGRIAEQMFLLAGRSHFADEK
HHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHCCCCC
PDAFMRMDDLAGTTLLMNSPSSVSKEMMHRIWRRDLYKRAVYTGREQLDMNRLSTLRPEE
CHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCH
KDRMKRAIAETAGVPDEKIILDIPPIRKEMRMMVQVQNQHDLVAFEEIIPLLSMMNATRQ
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
DQWRLGVFAPADILEKVGDAAREVLSLRRATKQDKLPGTIV
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKQIKDPVHGYIEVPTPLVPLLDTEVVQRLRYIKQLGFVYLVYPGANHTRFEHSLGAMH
CCCCCCCCCCEEECCCCCHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHH
LASLLARQLDLSKDDTLLVCTAALLHDIGHGPFSHASEKLRAEYGPFSHDDIAPLLIMPE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEECCC
ISDILDENGTDPHEIAGIVSGHHRLAEIIHGDLDVDRMDYLLRDAHYTGVPYGNLDAGRL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCHHHH
IQSLVLTEDGLAIKESGIAAAESLLIARTLMGPSVYYHHVGRIAEQMFLLAGRSHFADEK
HHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHCCCCC
PDAFMRMDDLAGTTLLMNSPSSVSKEMMHRIWRRDLYKRAVYTGREQLDMNRLSTLRPEE
CHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCH
KDRMKRAIAETAGVPDEKIILDIPPIRKEMRMMVQVQNQHDLVAFEEIIPLLSMMNATRQ
HHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
DQWRLGVFAPADILEKVGDAAREVLSLRRATKQDKLPGTIV
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]