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The map label for this gene is 124266136

Identifier: 124266136

GI number: 124266136

Start: 997024

End: 999399

Strand: Reverse

Name: 124266136

Synonym: Mpe_A0943

Alternate gene names: NA

Gene position: 999399-997024 (Counterclockwise)

Preceding gene: 124266137

Following gene: 124266135

Centisome position: 24.71

GC content: 65.24

Gene sequence:

>2376_bases
GTGAAGAATGCAACGTTCGGAAAAATCGAGAGGGCGTTCGAGCGCCTGATCCACCACCGCCGCTGGGTGGTGCTGACGGT
GGCGCTGCTGACGGCGGTGATGGGCTACCTGGCCACCCACGTCGAGGTGAAGACGATCTTCAGCGACCTGCTGCCGAAGA
ACCACCCCTATGTGGCGGTGAACCAGAAGTTCAAGTCGACCTTCGGCGGCTCGAACATGGTCAGCATCATGGTCGAGACC
GACAATGGCGACATCTTCGACACGAAGGTGCTGCAGAAGGTGCAGAAGCTGACGGTCGGCCTGCAACAGGTCGACAGCGT
CGACACCTACCAGATCGTCTCGATCGCCTCCAAGAAGATCAAGGAGGTGCGGGCCTCGACCGAGGGCGTGGAGTCGCGCC
CGATCATGTGGCCCAACCTGCCGCAGACCCCGGGCGAGATGGCGGTGCTGAAGGAGGCGGTGCTCAACAACCCGCTGATC
TACGGCCCCTACGTCTCGATGGACCTCAAGGCCACGCTGATCACGGCCGACTTCCTCGACGGCGAGATCAACTACAGCAA
GGCCTTCGACCAGATCATGGGCTTGGTCAAGGAGGCATCGGGCGACGGCGTCAAGGTGCGGGTGGTGGGCGAACCGGTGC
TGTACGGCTGGGTCAACTTCTACCTCGACGAGACGCTCAAGATCTTCTTCGCAGCGATCGCCTCGCTGGTGCTGATCCTG
ATGCTGATCACGCGCACCTGGCACGGCACCCTGCTGCCGCTGCTGGCCGGCGTGGTGAGCGCGATCTGGGCGCTCGGCGC
CGCCCGGTTGATGGGCTTCCACCTCGACCCGCTGGTGATCGTGGTGGCGTTCCTGATCACCGCGCAGGCGATCTCGAACT
CGGTGCAGCTGATATCGCGCTACGACGACGAGATCGCCGCCGGCGCCACCAGCTCGGCCGCCGCGGCCCTGGCCAGCGTG
AAGAACCTCTTCAAGCCCAGCATGCTGGCGATCGTGGCCGACGCCGGCTGCGTGCTGGTGGTGGCGCTCACGCCGATCCC
GATGCTGGAGAAGATCTCCTACATCGGCACGGTGTGGATCTTCTCGATCCTGGTCAGCGCGCTGCTGCTGACGCCGGTGA
TGCTGTCGTACTTCAAGCCGAAGCAGAGCTACGTACATCCACTGAACATCCGCCCGCTGCTCGACGCGGTGCTGCGCCTG
TGCGCCAAGATCGTGACCACGCGCTGGCGCTACGGCGTGCTGGGCACCGCGCTGGTGGTGTTCTTCGTGTCGGGCTGGTA
CGCCTTCAACCTGAAGGTCGGCGACGCGAACCCGGGTTCGCCGATCCTGTGGCCGGACTCCTCCTACAACCGAGACGCCA
CCGATATCAACCGCCAGTTCCAGGGTTCGGATCGCATGTTCGTGGTGGTCGCCGGCAAGGAGAAGGGTGCGCTGCGCGAG
CCGGAAGTGCTCAAGAGCATGAGCGACTTCCAGCGCTACATGGAGGCCCAGCCGGAGGTCGGCGGCAGCATCTCGCTGGC
CGACGTGCTGCCCCAGGTGCGCCGCGTGCTGCGCGAAGGCAACCCGATGTACGCCGAACTCGGCAACGACGCCAACGAGA
ACGGCGAGCTGACCTACATGTTCGTCTCCGGCTCCGACCCGGGCGACATGGACCGCTACGCCGACGCCGACGCGAAGAAC
GGCGCCGTGACCCTGTTCTTCCGCGACCACCAGGGCGAGACCATCCGCACCGCGATCGCCCGCGTGCAGGACTACGTGGC
GCAGAACGCGATGGAGAAGGCGGACTACCTGCTGGCCGGCGGCCTGGTGGGCGTGCTGGCGGCGGTGAACGAGGTCATCC
TCGCGGGTCAGATCGAGGCCATCGCGCTGGCACTGCTGGTGCTGGTGGTGTGCTGCACGGTGACCTACCGCTCCACCGTG
GCCGGGGTGTTCTTCATGATCCCGGTGATGCTGTCCAACACCATCACGTTCAGCTACATGGCCTGGCACGGCATCGGCAT
GAACATCAACACGCTGCCGGTGGTGGCGCTGGGCATCGGCCTGGGGGTGGACTACACCTTCTACATCGTCGACGGCATCC
GCGAGGAACTGCACCACTCCGACAACGTCGAGGCCGCCATCATCAAGGCGCTCAGCAGCGCCGGCCGCGGGGTCCTGATC
ACCGCGCTCACGCTGATCACCAGCGTCGGGCTGTGGAGCTTCTCGTCGCTGCGGCTGCAGGCCGACATGGGCCTGCTGAT
CGCGCTCTGGCTGTTCATCTCGGCCTTCAGCGCGCTCTTCATCATGCCGGCGATCGTCTACGTGTTCCGCCCCGCCTTCA
TCGTGGGCAGCAAGCAGCGCCCGATCGAGCGCGCCAGTTCCGCAGTGGTTGTGTGA

Upstream 100 bases:

>100_bases
GGCCCGCGCTACTACCTGGCCGGCGCCAACCTCGCCGTGCTCGAAGGCGACCAGCTGACCGTCGCCGGTCGCTGACACGA
ACAAAAAGGAGGAGACGGCT

Downstream 100 bases:

>100_bases
GGGTGCCAGCCACTCGCGACGGCGCCGCTCCGGCGACGCCGTGCGGATCCGTGCTGGCTAATTTCTGGTTCTAGTGAAAA
GACGAAAGGAACGGAGACAT

Product: RND efflux transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MKNATFGKIERAFERLIHHRRWVVLTVALLTAVMGYLATHVEVKTIFSDLLPKNHPYVAVNQKFKSTFGGSNMVSIMVET
DNGDIFDTKVLQKVQKLTVGLQQVDSVDTYQIVSIASKKIKEVRASTEGVESRPIMWPNLPQTPGEMAVLKEAVLNNPLI
YGPYVSMDLKATLITADFLDGEINYSKAFDQIMGLVKEASGDGVKVRVVGEPVLYGWVNFYLDETLKIFFAAIASLVLIL
MLITRTWHGTLLPLLAGVVSAIWALGAARLMGFHLDPLVIVVAFLITAQAISNSVQLISRYDDEIAAGATSSAAAALASV
KNLFKPSMLAIVADAGCVLVVALTPIPMLEKISYIGTVWIFSILVSALLLTPVMLSYFKPKQSYVHPLNIRPLLDAVLRL
CAKIVTTRWRYGVLGTALVVFFVSGWYAFNLKVGDANPGSPILWPDSSYNRDATDINRQFQGSDRMFVVVAGKEKGALRE
PEVLKSMSDFQRYMEAQPEVGGSISLADVLPQVRRVLREGNPMYAELGNDANENGELTYMFVSGSDPGDMDRYADADAKN
GAVTLFFRDHQGETIRTAIARVQDYVAQNAMEKADYLLAGGLVGVLAAVNEVILAGQIEAIALALLVLVVCCTVTYRSTV
AGVFFMIPVMLSNTITFSYMAWHGIGMNINTLPVVALGIGLGVDYTFYIVDGIREELHHSDNVEAAIIKALSSAGRGVLI
TALTLITSVGLWSFSSLRLQADMGLLIALWLFISAFSALFIMPAIVYVFRPAFIVGSKQRPIERASSAVVV

Sequences:

>Translated_791_residues
MKNATFGKIERAFERLIHHRRWVVLTVALLTAVMGYLATHVEVKTIFSDLLPKNHPYVAVNQKFKSTFGGSNMVSIMVET
DNGDIFDTKVLQKVQKLTVGLQQVDSVDTYQIVSIASKKIKEVRASTEGVESRPIMWPNLPQTPGEMAVLKEAVLNNPLI
YGPYVSMDLKATLITADFLDGEINYSKAFDQIMGLVKEASGDGVKVRVVGEPVLYGWVNFYLDETLKIFFAAIASLVLIL
MLITRTWHGTLLPLLAGVVSAIWALGAARLMGFHLDPLVIVVAFLITAQAISNSVQLISRYDDEIAAGATSSAAAALASV
KNLFKPSMLAIVADAGCVLVVALTPIPMLEKISYIGTVWIFSILVSALLLTPVMLSYFKPKQSYVHPLNIRPLLDAVLRL
CAKIVTTRWRYGVLGTALVVFFVSGWYAFNLKVGDANPGSPILWPDSSYNRDATDINRQFQGSDRMFVVVAGKEKGALRE
PEVLKSMSDFQRYMEAQPEVGGSISLADVLPQVRRVLREGNPMYAELGNDANENGELTYMFVSGSDPGDMDRYADADAKN
GAVTLFFRDHQGETIRTAIARVQDYVAQNAMEKADYLLAGGLVGVLAAVNEVILAGQIEAIALALLVLVVCCTVTYRSTV
AGVFFMIPVMLSNTITFSYMAWHGIGMNINTLPVVALGIGLGVDYTFYIVDGIREELHHSDNVEAAIIKALSSAGRGVLI
TALTLITSVGLWSFSSLRLQADMGLLIALWLFISAFSALFIMPAIVYVFRPAFIVGSKQRPIERASSAVVV
>Mature_791_residues
MKNATFGKIERAFERLIHHRRWVVLTVALLTAVMGYLATHVEVKTIFSDLLPKNHPYVAVNQKFKSTFGGSNMVSIMVET
DNGDIFDTKVLQKVQKLTVGLQQVDSVDTYQIVSIASKKIKEVRASTEGVESRPIMWPNLPQTPGEMAVLKEAVLNNPLI
YGPYVSMDLKATLITADFLDGEINYSKAFDQIMGLVKEASGDGVKVRVVGEPVLYGWVNFYLDETLKIFFAAIASLVLIL
MLITRTWHGTLLPLLAGVVSAIWALGAARLMGFHLDPLVIVVAFLITAQAISNSVQLISRYDDEIAAGATSSAAAALASV
KNLFKPSMLAIVADAGCVLVVALTPIPMLEKISYIGTVWIFSILVSALLLTPVMLSYFKPKQSYVHPLNIRPLLDAVLRL
CAKIVTTRWRYGVLGTALVVFFVSGWYAFNLKVGDANPGSPILWPDSSYNRDATDINRQFQGSDRMFVVVAGKEKGALRE
PEVLKSMSDFQRYMEAQPEVGGSISLADVLPQVRRVLREGNPMYAELGNDANENGELTYMFVSGSDPGDMDRYADADAKN
GAVTLFFRDHQGETIRTAIARVQDYVAQNAMEKADYLLAGGLVGVLAAVNEVILAGQIEAIALALLVLVVCCTVTYRSTV
AGVFFMIPVMLSNTITFSYMAWHGIGMNINTLPVVALGIGLGVDYTFYIVDGIREELHHSDNVEAAIIKALSSAGRGVLI
TALTLITSVGLWSFSSLRLQADMGLLIALWLFISAFSALFIMPAIVYVFRPAFIVGSKQRPIERASSAVVV

Specific function: Unknown

COG id: COG1033

COG function: function code R; Predicted exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 86322; Mature: 86322

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNATFGKIERAFERLIHHRRWVVLTVALLTAVMGYLATHVEVKTIFSDLLPKNHPYVAV
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
NQKFKSTFGGSNMVSIMVETDNGDIFDTKVLQKVQKLTVGLQQVDSVDTYQIVSIASKKI
CHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEVRASTEGVESRPIMWPNLPQTPGEMAVLKEAVLNNPLIYGPYVSMDLKATLITADFLD
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCEECCEEEEEEEEEECCC
GEINYSKAFDQIMGLVKEASGDGVKVRVVGEPVLYGWVNFYLDETLKIFFAAIASLVLIL
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLITRTWHGTLLPLLAGVVSAIWALGAARLMGFHLDPLVIVVAFLITAQAISNSVQLISR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YDDEIAAGATSSAAAALASVKNLFKPSMLAIVADAGCVLVVALTPIPMLEKISYIGTVWI
HCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHEECCCEEEEEEECCCHHHHHHHHHHHHHH
FSILVSALLLTPVMLSYFKPKQSYVHPLNIRPLLDAVLRLCAKIVTTRWRYGVLGTALVV
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVSGWYAFNLKVGDANPGSPILWPDSSYNRDATDINRQFQGSDRMFVVVAGKEKGALRE
HHHCCEEEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCC
PEVLKSMSDFQRYMEAQPEVGGSISLADVLPQVRRVLREGNPMYAELGNDANENGELTYM
CHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEE
FVSGSDPGDMDRYADADAKNGAVTLFFRDHQGETIRTAIARVQDYVAQNAMEKADYLLAG
EEECCCCCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVGVLAAVNEVILAGQIEAIALALLVLVVCCTVTYRSTVAGVFFMIPVMLSNTITFSYM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH
AWHGIGMNINTLPVVALGIGLGVDYTFYIVDGIREELHHSDNVEAAIIKALSSAGRGVLI
EEECCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
TALTLITSVGLWSFSSLRLQADMGLLIALWLFISAFSALFIMPAIVYVFRPAFIVGSKQR
HHHHHHHHHHHCCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCC
PIERASSAVVV
CHHHCCCCCCC
>Mature Secondary Structure
MKNATFGKIERAFERLIHHRRWVVLTVALLTAVMGYLATHVEVKTIFSDLLPKNHPYVAV
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
NQKFKSTFGGSNMVSIMVETDNGDIFDTKVLQKVQKLTVGLQQVDSVDTYQIVSIASKKI
CHHHHHCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KEVRASTEGVESRPIMWPNLPQTPGEMAVLKEAVLNNPLIYGPYVSMDLKATLITADFLD
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEECCEECCEEEEEEEEEECCC
GEINYSKAFDQIMGLVKEASGDGVKVRVVGEPVLYGWVNFYLDETLKIFFAAIASLVLIL
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLITRTWHGTLLPLLAGVVSAIWALGAARLMGFHLDPLVIVVAFLITAQAISNSVQLISR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
YDDEIAAGATSSAAAALASVKNLFKPSMLAIVADAGCVLVVALTPIPMLEKISYIGTVWI
HCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHEECCCEEEEEEECCCHHHHHHHHHHHHHH
FSILVSALLLTPVMLSYFKPKQSYVHPLNIRPLLDAVLRLCAKIVTTRWRYGVLGTALVV
HHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVSGWYAFNLKVGDANPGSPILWPDSSYNRDATDINRQFQGSDRMFVVVAGKEKGALRE
HHHCCEEEEEEEECCCCCCCCEECCCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCCC
PEVLKSMSDFQRYMEAQPEVGGSISLADVLPQVRRVLREGNPMYAELGNDANENGELTYM
CHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEE
FVSGSDPGDMDRYADADAKNGAVTLFFRDHQGETIRTAIARVQDYVAQNAMEKADYLLAG
EEECCCCCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVGVLAAVNEVILAGQIEAIALALLVLVVCCTVTYRSTVAGVFFMIPVMLSNTITFSYM
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEH
AWHGIGMNINTLPVVALGIGLGVDYTFYIVDGIREELHHSDNVEAAIIKALSSAGRGVLI
EEECCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHH
TALTLITSVGLWSFSSLRLQADMGLLIALWLFISAFSALFIMPAIVYVFRPAFIVGSKQR
HHHHHHHHHHHCCCHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCC
PIERASSAVVV
CHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]