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The map label for this gene is gdhII [H]

Identifier: 124266101

GI number: 124266101

Start: 962583

End: 963323

Strand: Reverse

Name: gdhII [H]

Synonym: Mpe_A0908

Alternate gene names: 124266101

Gene position: 963323-962583 (Counterclockwise)

Preceding gene: 124266102

Following gene: 124266100

Centisome position: 23.82

GC content: 72.06

Gene sequence:

>741_bases
ATGGGCCTTCCAACCGCCGTCGTCGTCGGCGTGGGTGTCGAGCAGGGCGTGGGCGGCGCTGTCTGCCGGCGCTTCGCAGC
CGAGGGCTACCACGTCCTCGCGGCGGGGCACACCGCCGCCAAGATCGGCCAGGTGGTCGACGCCATCCGCGCGGCCGGCG
GCAGCGCGCAGGCCGTCGTCACCGACACCACCTCGGAAACCGATGTCGAGCGGCTGTTCGACCTGGCCATGACGCCGGGT
GCGGGCCGCGAACCGGCCGATCTGGTGGTGTTCAACGCCGGCAACAACCAGGTGATCGATTTCCGCACGCTCACCGCGGC
GCAGTTCGAGAGCTTCTGGCGCGTCGGCTGCTTCGGCGGCTTCCTGGTCGGCCGCGAGGCGGCGCGGCGCCTGGCACCGC
TGGGGCGCGGCACGGTGATCTTCACCGGCGCCTCGGGCAGCCTGCGCGGCAAGCCGGGCTTCGCCCACTTCGCTGCGGCC
AAGGCCGGGCTGCGCATGCTGAGCCAGAGCATGGCGCGCGAGTTCGGCCCCCTGGGCCTCCACGTGGCCCACGTCGTGAT
CGACGGCGGCATCAACGGCGAGCGCCTGCGCAGCGTGATGCCGAAGATGGTGGCGCAGCGCGGCGAGGACGGTCTGCTCG
ACGTCGATGCGATCGCCGAGACCTACTGGCAGCTCCACCGCCAGCCCCGCAGCGCGTGGGCGCAGGAGATCGACCTGCGC
CCCTACAAGGAATCGTTCTGA

Upstream 100 bases:

>100_bases
ACGGGTCGATGCGTCCGGAGCGCAGCGGCACGGCAAGGCACCGAGCATGCCCGCTGAGATTCGCCTGAACCCGCAACCGA
GTTCATTGGTGGAGAACAGC

Downstream 100 bases:

>100_bases
GCCCCCGTGCGCGCACACCCGTGCGCGCTTGATCGTCAATGTTCGTCACAACAGGAGACCCGCTTGAAACTGCTCAATTC
CTTCGGCCCCAATCCCCGCA

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: GLCDH-II [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MGLPTAVVVGVGVEQGVGGAVCRRFAAEGYHVLAAGHTAAKIGQVVDAIRAAGGSAQAVVTDTTSETDVERLFDLAMTPG
AGREPADLVVFNAGNNQVIDFRTLTAAQFESFWRVGCFGGFLVGREAARRLAPLGRGTVIFTGASGSLRGKPGFAHFAAA
KAGLRMLSQSMAREFGPLGLHVAHVVIDGGINGERLRSVMPKMVAQRGEDGLLDVDAIAETYWQLHRQPRSAWAQEIDLR
PYKESF

Sequences:

>Translated_246_residues
MGLPTAVVVGVGVEQGVGGAVCRRFAAEGYHVLAAGHTAAKIGQVVDAIRAAGGSAQAVVTDTTSETDVERLFDLAMTPG
AGREPADLVVFNAGNNQVIDFRTLTAAQFESFWRVGCFGGFLVGREAARRLAPLGRGTVIFTGASGSLRGKPGFAHFAAA
KAGLRMLSQSMAREFGPLGLHVAHVVIDGGINGERLRSVMPKMVAQRGEDGLLDVDAIAETYWQLHRQPRSAWAQEIDLR
PYKESF
>Mature_245_residues
GLPTAVVVGVGVEQGVGGAVCRRFAAEGYHVLAAGHTAAKIGQVVDAIRAAGGSAQAVVTDTTSETDVERLFDLAMTPGA
GREPADLVVFNAGNNQVIDFRTLTAAQFESFWRVGCFGGFLVGREAARRLAPLGRGTVIFTGASGSLRGKPGFAHFAAAK
AGLRMLSQSMAREFGPLGLHVAHVVIDGGINGERLRSVMPKMVAQRGEDGLLDVDAIAETYWQLHRQPRSAWAQEIDLRP
YKESF

Specific function: Sorbitol metabolism. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=29.2553191489362, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 26048; Mature: 25917

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPTAVVVGVGVEQGVGGAVCRRFAAEGYHVLAAGHTAAKIGQVVDAIRAAGGSAQAVV
CCCCCEEEEECCHHCCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEE
TDTTSETDVERLFDLAMTPGAGREPADLVVFNAGNNQVIDFRTLTAAQFESFWRVGCFGG
ECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHH
FLVGREAARRLAPLGRGTVIFTGASGSLRGKPGFAHFAAAKAGLRMLSQSMAREFGPLGL
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
HVAHVVIDGGINGERLRSVMPKMVAQRGEDGLLDVDAIAETYWQLHRQPRSAWAQEIDLR
EEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHCCCC
PYKESF
CCCCCC
>Mature Secondary Structure 
GLPTAVVVGVGVEQGVGGAVCRRFAAEGYHVLAAGHTAAKIGQVVDAIRAAGGSAQAVV
CCCCEEEEECCHHCCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEE
TDTTSETDVERLFDLAMTPGAGREPADLVVFNAGNNQVIDFRTLTAAQFESFWRVGCFGG
ECCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHH
FLVGREAARRLAPLGRGTVIFTGASGSLRGKPGFAHFAAAKAGLRMLSQSMAREFGPLGL
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
HVAHVVIDGGINGERLRSVMPKMVAQRGEDGLLDVDAIAETYWQLHRQPRSAWAQEIDLR
EEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHCCCC
PYKESF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA