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The map label for this gene is accD [H]

Identifier: 124265985

GI number: 124265985

Start: 826644

End: 827579

Strand: Reverse

Name: accD [H]

Synonym: Mpe_A0792

Alternate gene names: 124265985

Gene position: 827579-826644 (Counterclockwise)

Preceding gene: 124265986

Following gene: 124265984

Centisome position: 20.46

GC content: 74.57

Gene sequence:

>936_bases
ATGAGCAGCGAACGCCCCGACGCCGCCGCCGTGCTGTCGCCGCAGGCCGCGCGCAGCTTCTACGAAGCCAACGCGCGCCA
GCGCGTGCGCGGCCTGTTCGACGCCGGCTCGGTGCACGAATGGCTGCCGCCGTCGCAGCGCATCGTCAGCCCGCACCTCG
AGCAGCTCGGCCAGCCGCGTGCGCTGGACGACGGCGTGATGATCGGCCGCGCCACGCTGGCCGGCCGGCCGGTGCTGTTC
GCGGCCGAGGAGCCCGGCTTCATGGGCGGCTCGGTCGGCGAAGTGCACGGCGCCAAGCTCACCGGCCTGCTGGAACGCGC
CGCGCGCGACCGGCCGGCCGCCGTGGTGCTGCTGCTCGACACCGGCGGCGTGCGCCTGCACGAGGCCAACGCGGGGCTGA
TCGCGATCTCGGAGATCCAGCGCGCGGTGTTCTCCGCGCGCGCCGCCGGCGTGCCGGTGATCGTGGTCTCGGGCGGGGCC
AACGGCTGCTACGGCGGGCTGGGCATCGTGGCGCGCTGCTGCGACCACATCGTGATGACCGAGGAAGGCCGGCTCTCGGT
GTCGGGGCCGGAGGTGATCGAGTCGCAGAAGGGCGTGGAGGAGTTCGACGCCAAGGACCGCGCGCTGGTGTGGCGCACGA
TGGGCGGCAAGCACCGCTACCTGATCGGCGAGGCCGACGGCTTCGCGCGCGACACGATGGACGACCTGCGGCAGGCGGTC
GCGGCCTTCTTCGACCGGCCGGTGCCGCTGACGCTGGAGGCGGTGGAGCGCGAGCACGCGGCGCTCGGCCGCCGGCTCGA
GCGCTTCGGCGCGGCGCCCGATGCCGTCGACATCTGGTCGGGCCTGGGTGTGGCCGAGCCGCGGCAGCTGCCGCTGCTCG
ACACCGAGGCCTTCACCGCCCTCGCCGACCGCGTGAAGGAGCGCGGCGATGTCTGA

Upstream 100 bases:

>100_bases
GACACCGCGTCGGCAACCTGCTGGTCACCGTGAACGACGCCGGCGCCACCCCCTCGGTGGTGGCGCTGCGCCTGGCGCAG
GCGATGGAGGAGCTGCGCGG

Downstream 100 bases:

>100_bases
GGCCCGCAGCCCCGCACTGGCCCTGTGCGACGGCTTGTTTCCCGGCGGCCACGACGTGCGCGCCGAAGGCCTGCTGCTGT
GGGGCAGCGGGCGCACGGCC

Product: subunit beta of malonate decarboxylase

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSSERPDAAAVLSPQAARSFYEANARQRVRGLFDAGSVHEWLPPSQRIVSPHLEQLGQPRALDDGVMIGRATLAGRPVLF
AAEEPGFMGGSVGEVHGAKLTGLLERAARDRPAAVVLLLDTGGVRLHEANAGLIAISEIQRAVFSARAAGVPVIVVSGGA
NGCYGGLGIVARCCDHIVMTEEGRLSVSGPEVIESQKGVEEFDAKDRALVWRTMGGKHRYLIGEADGFARDTMDDLRQAV
AAFFDRPVPLTLEAVEREHAALGRRLERFGAAPDAVDIWSGLGVAEPRQLPLLDTEAFTALADRVKERGDV

Sequences:

>Translated_311_residues
MSSERPDAAAVLSPQAARSFYEANARQRVRGLFDAGSVHEWLPPSQRIVSPHLEQLGQPRALDDGVMIGRATLAGRPVLF
AAEEPGFMGGSVGEVHGAKLTGLLERAARDRPAAVVLLLDTGGVRLHEANAGLIAISEIQRAVFSARAAGVPVIVVSGGA
NGCYGGLGIVARCCDHIVMTEEGRLSVSGPEVIESQKGVEEFDAKDRALVWRTMGGKHRYLIGEADGFARDTMDDLRQAV
AAFFDRPVPLTLEAVEREHAALGRRLERFGAAPDAVDIWSGLGVAEPRQLPLLDTEAFTALADRVKERGDV
>Mature_310_residues
SSERPDAAAVLSPQAARSFYEANARQRVRGLFDAGSVHEWLPPSQRIVSPHLEQLGQPRALDDGVMIGRATLAGRPVLFA
AEEPGFMGGSVGEVHGAKLTGLLERAARDRPAAVVLLLDTGGVRLHEANAGLIAISEIQRAVFSARAAGVPVIVVSGGAN
GCYGGLGIVARCCDHIVMTEEGRLSVSGPEVIESQKGVEEFDAKDRALVWRTMGGKHRYLIGEADGFARDTMDDLRQAVA
AFFDRPVPLTLEAVEREHAALGRRLERFGAAPDAVDIWSGLGVAEPRQLPLLDTEAFTALADRVKERGDV

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=186, Percent_Identity=28.494623655914, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 33201; Mature: 33070

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSERPDAAAVLSPQAARSFYEANARQRVRGLFDAGSVHEWLPPSQRIVSPHLEQLGQPR
CCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHCCHHHHHCCCCC
ALDDGVMIGRATLAGRPVLFAAEEPGFMGGSVGEVHGAKLTGLLERAARDRPAAVVLLLD
CCCCCEEEEEHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
TGGVRLHEANAGLIAISEIQRAVFSARAAGVPVIVVSGGANGCYGGLGIVARCCDHIVMT
CCCEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEC
EEGRLSVSGPEVIESQKGVEEFDAKDRALVWRTMGGKHRYLIGEADGFARDTMDDLRQAV
CCCCEECCCHHHHHHHCCHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHH
AAFFDRPVPLTLEAVEREHAALGRRLERFGAAPDAVDIWSGLGVAEPRQLPLLDTEAFTA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHH
LADRVKERGDV
HHHHHHHHCCC
>Mature Secondary Structure 
SSERPDAAAVLSPQAARSFYEANARQRVRGLFDAGSVHEWLPPSQRIVSPHLEQLGQPR
CCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHCCHHHHHCCCCC
ALDDGVMIGRATLAGRPVLFAAEEPGFMGGSVGEVHGAKLTGLLERAARDRPAAVVLLLD
CCCCCEEEEEHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEE
TGGVRLHEANAGLIAISEIQRAVFSARAAGVPVIVVSGGANGCYGGLGIVARCCDHIVMT
CCCEEEEECCCCEEEHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEC
EEGRLSVSGPEVIESQKGVEEFDAKDRALVWRTMGGKHRYLIGEADGFARDTMDDLRQAV
CCCCEECCCHHHHHHHCCHHHHCCCCCEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHH
AAFFDRPVPLTLEAVEREHAALGRRLERFGAAPDAVDIWSGLGVAEPRQLPLLDTEAFTA
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHH
LADRVKERGDV
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]