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The map label for this gene is ydcR [H]

Identifier: 124265945

GI number: 124265945

Start: 780447

End: 781877

Strand: Reverse

Name: ydcR [H]

Synonym: Mpe_A0752

Alternate gene names: 124265945

Gene position: 781877-780447 (Counterclockwise)

Preceding gene: 124265949

Following gene: 124265944

Centisome position: 19.33

GC content: 74.84

Gene sequence:

>1431_bases
ATGAAACGCTACGAACGCTATGCCGACGAGATCGCGCGGCTGATCGCCGACCGCGCGCTGCAGCCCGGCGACCGCCTGCC
GTCGGTGCGCCAGGCCAGCGCGCACCGCGGCATCAGCCCGGCCACGGTGTTCCAGGCCTACTACCTGCTGGAGTCGCGCG
GGCTGGCCGAGGCACGGCCCCGCTCGGGCTACTACGTGGCGGCGCGCGCGCTGCCGGCGCCGGCCGAGCCGCGGCTGTCG
CGGCCGCGGCGGCGCTCCAGCGGCGTGGAGGTCAGCGAGCTGGTGTTCGAGGTGCTGGGCTCGGTGAAGGACCGCGACGT
GGTGCCGCTGGGCTCGGCCTTCCCGAGCCCGCAGCTGTTCCCGATGGCGCAGCTGGCGCGCGGGCTGGCGGCCGGGCTGA
AGCGCCTGGACCCCTGGCGCACGGTGGAAGACCTGACGCCGGGCAGCGCCCGGCTGCGCGAGCAGATCGCGCTGCGCTAC
CGGCTCGACGGCCTGGAGGTGAGCGCCGAGGAGATCGTCATCACCAACGGCGCGCTGGAGGCGCTGAACCTCAGCCTGCA
GGCGCTCACGCGGCCGGGCGACACGGTGATCGTGGAGTCGCCCACCTTCTATGCCGCGCTGCAGGCGCTGGAGCAGCAGC
ACCTGAAGGCGCTGGAGGTGGCGACCCACCCGCGCACCGGCATCGACCTCGCGGCGCTGGCGCAGGCGCTGGAGCGCCAC
ACGGTGAAGGCCTGCTGGCTGATGCCCAATTTCCAGAACCCGCTGGGCAGCCTGATGCCCGACGCGAACAAGCAGGCGCT
GGTGGAGCTGCTGGCCGCGCACGGCGTGCCGCTGATCGAGGACGACGTGTACGGCGAGCTGCACCACGGCACGCGCCGCC
CGCCGCCGGCCAAGGCCTGGGACCGTGCGGGCGGCGTGCTGCACTGCGCCTCGTTCTCCAAGAGCCTGGCGCCGGGCTAC
CGCGTGGGCTGGGTGGCGGCCGGCCGGCACGCGCAGGCGATCGAGCGGCGCAAGCTGATGACCACGCTGTCGGCGGCGGT
GCCGTCGCAGCTGGCGCTGTCGGAGTACCTCGACCGCGGCGGCTACGACCGCCATCTGCGCCGGCTGCGCCCCGCGCTGG
CGCGCCAGCAGACGCTGGCCCTGCGCACCATCGCCCGCCATTTCCCCGCCGGCACGCGCGTGGCGCGGCCCGAGGGCGGC
TACTTCCTGTGGATCGAGCTGCCGGCGAGCGTGGACGCGCTGGCGCTGCACCGGCTGGCGCTGGCGCAGCGCATCAGCCT
CGCGCCGGGCCAGCTGTTCTCGACCGACCGGCGATTCCGCCACCACGTGCGCCTGAACCACGGCCACCCGGACGACCCGC
GCTTCGAATCCGCCCTGCAGACGGTGGGCCGGCTGGCCGGCGAACTGGCCGCCGCGGGCCGCGTCGCCTGA

Upstream 100 bases:

>100_bases
AAGGCTCAGATCGACGCAAAAAAACCAGATCAGTTTGCCGGCTTTCTTGAAATTCCTTGCTTTCTGATCAGTACAGTCGG
GCCACAGCCCTCCGCGCCCG

Downstream 100 bases:

>100_bases
AGCGCACGCACGGCGCCGGAACCCCGGCCCGTCCGGCCGCTCGAAGCAGCTCCCCCACTCCCCGCCGTCGCACCATGCAG
CTCGCCCTCTGGCTCTTCAC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MKRYERYADEIARLIADRALQPGDRLPSVRQASAHRGISPATVFQAYYLLESRGLAEARPRSGYYVAARALPAPAEPRLS
RPRRRSSGVEVSELVFEVLGSVKDRDVVPLGSAFPSPQLFPMAQLARGLAAGLKRLDPWRTVEDLTPGSARLREQIALRY
RLDGLEVSAEEIVITNGALEALNLSLQALTRPGDTVIVESPTFYAALQALEQQHLKALEVATHPRTGIDLAALAQALERH
TVKACWLMPNFQNPLGSLMPDANKQALVELLAAHGVPLIEDDVYGELHHGTRRPPPAKAWDRAGGVLHCASFSKSLAPGY
RVGWVAAGRHAQAIERRKLMTTLSAAVPSQLALSEYLDRGGYDRHLRRLRPALARQQTLALRTIARHFPAGTRVARPEGG
YFLWIELPASVDALALHRLALAQRISLAPGQLFSTDRRFRHHVRLNHGHPDDPRFESALQTVGRLAGELAAAGRVA

Sequences:

>Translated_476_residues
MKRYERYADEIARLIADRALQPGDRLPSVRQASAHRGISPATVFQAYYLLESRGLAEARPRSGYYVAARALPAPAEPRLS
RPRRRSSGVEVSELVFEVLGSVKDRDVVPLGSAFPSPQLFPMAQLARGLAAGLKRLDPWRTVEDLTPGSARLREQIALRY
RLDGLEVSAEEIVITNGALEALNLSLQALTRPGDTVIVESPTFYAALQALEQQHLKALEVATHPRTGIDLAALAQALERH
TVKACWLMPNFQNPLGSLMPDANKQALVELLAAHGVPLIEDDVYGELHHGTRRPPPAKAWDRAGGVLHCASFSKSLAPGY
RVGWVAAGRHAQAIERRKLMTTLSAAVPSQLALSEYLDRGGYDRHLRRLRPALARQQTLALRTIARHFPAGTRVARPEGG
YFLWIELPASVDALALHRLALAQRISLAPGQLFSTDRRFRHHVRLNHGHPDDPRFESALQTVGRLAGELAAAGRVA
>Mature_476_residues
MKRYERYADEIARLIADRALQPGDRLPSVRQASAHRGISPATVFQAYYLLESRGLAEARPRSGYYVAARALPAPAEPRLS
RPRRRSSGVEVSELVFEVLGSVKDRDVVPLGSAFPSPQLFPMAQLARGLAAGLKRLDPWRTVEDLTPGSARLREQIALRY
RLDGLEVSAEEIVITNGALEALNLSLQALTRPGDTVIVESPTFYAALQALEQQHLKALEVATHPRTGIDLAALAQALERH
TVKACWLMPNFQNPLGSLMPDANKQALVELLAAHGVPLIEDDVYGELHHGTRRPPPAKAWDRAGGVLHCASFSKSLAPGY
RVGWVAAGRHAQAIERRKLMTTLSAAVPSQLALSEYLDRGGYDRHLRRLRPALARQQTLALRTIARHFPAGTRVARPEGG
YFLWIELPASVDALALHRLALAQRISLAPGQLFSTDRRFRHHVRLNHGHPDDPRFESALQTVGRLAGELAAAGRVA

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=317, Percent_Identity=24.9211356466877, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI33469970, Length=317, Percent_Identity=24.9211356466877, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4507369, Length=176, Percent_Identity=27.8409090909091, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=51.2820512820513, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1790797, Length=469, Percent_Identity=39.6588486140725, Blast_Score=317, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6321000, Length=341, Percent_Identity=25.2199413489736, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356535, Length=319, Percent_Identity=23.5109717868339, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52296; Mature: 52296

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYERYADEIARLIADRALQPGDRLPSVRQASAHRGISPATVFQAYYLLESRGLAEARP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
RSGYYVAARALPAPAEPRLSRPRRRSSGVEVSELVFEVLGSVKDRDVVPLGSAFPSPQLF
CCCEEEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PMAQLARGLAAGLKRLDPWRTVEDLTPGSARLREQIALRYRLDGLEVSAEEIVITNGALE
HHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHEECCCEECCCEEEEECCCHH
ALNLSLQALTRPGDTVIVESPTFYAALQALEQQHLKALEVATHPRTGIDLAALAQALERH
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TVKACWLMPNFQNPLGSLMPDANKQALVELLAAHGVPLIEDDVYGELHHGTRRPPPAKAW
HHHHEEECCCCCCHHHHHCCCCCHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCCHH
DRAGGVLHCASFSKSLAPGYRVGWVAAGRHAQAIERRKLMTTLSAAVPSQLALSEYLDRG
HHCCCEEEEHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
GYDRHLRRLRPALARQQTLALRTIARHFPAGTRVARPEGGYFLWIELPASVDALALHRLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHH
LAQRISLAPGQLFSTDRRFRHHVRLNHGHPDDPRFESALQTVGRLAGELAAAGRVA
HHHHHCCCCCHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRYERYADEIARLIADRALQPGDRLPSVRQASAHRGISPATVFQAYYLLESRGLAEARP
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCC
RSGYYVAARALPAPAEPRLSRPRRRSSGVEVSELVFEVLGSVKDRDVVPLGSAFPSPQLF
CCCEEEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
PMAQLARGLAAGLKRLDPWRTVEDLTPGSARLREQIALRYRLDGLEVSAEEIVITNGALE
HHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHEECCCEECCCEEEEECCCHH
ALNLSLQALTRPGDTVIVESPTFYAALQALEQQHLKALEVATHPRTGIDLAALAQALERH
HHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
TVKACWLMPNFQNPLGSLMPDANKQALVELLAAHGVPLIEDDVYGELHHGTRRPPPAKAW
HHHHEEECCCCCCHHHHHCCCCCHHHHHHHHHHCCCCEECCCCCHHHHCCCCCCCCCCHH
DRAGGVLHCASFSKSLAPGYRVGWVAAGRHAQAIERRKLMTTLSAAVPSQLALSEYLDRG
HHCCCEEEEHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
GYDRHLRRLRPALARQQTLALRTIARHFPAGTRVARPEGGYFLWIELPASVDALALHRLA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCHHHHHHHHHH
LAQRISLAPGQLFSTDRRFRHHVRLNHGHPDDPRFESALQTVGRLAGELAAAGRVA
HHHHHCCCCCHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]