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The map label for this gene is doxJ [H]

Identifier: 124265937

GI number: 124265937

Start: 773198

End: 773803

Strand: Direct

Name: doxJ [H]

Synonym: Mpe_A0744

Alternate gene names: 124265937

Gene position: 773198-773803 (Clockwise)

Preceding gene: 124265936

Following gene: 124265939

Centisome position: 19.12

GC content: 67.0

Gene sequence:

>606_bases
ATGAGCGCCGCGCCGATCGAGTTCTGGTTCGAGTTCGCCAGCAACTACAGCTACCTCAGCGTGATGCGCATCGAGGACTG
CGCTGCCCGGCGCGGCGTGCAAGTCCGCTGGAAGCCCTTCCTGCTGGGGCCGATCTTCCGGAGCTTTGGCTGGCAGACAT
CGCCCTTCGTGCTGCAGAAGGCCAAGGGCGACTACGTCTGGCAGGACATGGTGCGCCAGTGCCGCAAGTACGACCTGGCA
TGGACCCGGCCCTCGGGCTTTCCCCGCTCGTCGCTGCTGCCCTCACGCGTGGCGCTCGTGGGGGCCGAGCAGGATTGGAT
CGGCGCCTACTGCCGGCGCGTGATGTCGATCAACTTCGGCGAGGACCGGGAGATCGATACGAACAAGGTGGTGACGGAGG
TGCTCACGGCGCTCGGCCTGCCGGCACGGCAGATCATCGACGAGGCGCAGTCCGAGGCCAACAAGCTGCGGCTGAGGCAG
CAGACGGAGACGGCGGCGCGGCGAGGGATCTTCGGTGCGCCGATGTTCTTCGTGGGCGACGACATGTTCTGGGGCAACGA
TCGCCTGGACGATGCCCTGGACCACTGCGTCCAGGCGCCGGCGTAG

Upstream 100 bases:

>100_bases
TCACACCGCACACCGCCTTCGACCTGCCCGACATCCCCGCCGGCGCGCCGCTGCGCGAGAGCATCGAGCTGCGCTGCCTC
GTGGTCTACGGAGACGCGCA

Downstream 100 bases:

>100_bases
GGACGACTCAGGAACGCCGGGCGCGCGGCTTCGGTGCCGTCTGCGGGGGCGCGAGAGCGGGCTCGGCCGACATTCGCGCC
TCGCTTTCTATCCACTCCGC

Product: 2-hydroxychromene-2-carboxylate isomerase family protein

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSAAPIEFWFEFASNYSYLSVMRIEDCAARRGVQVRWKPFLLGPIFRSFGWQTSPFVLQKAKGDYVWQDMVRQCRKYDLA
WTRPSGFPRSSLLPSRVALVGAEQDWIGAYCRRVMSINFGEDREIDTNKVVTEVLTALGLPARQIIDEAQSEANKLRLRQ
QTETAARRGIFGAPMFFVGDDMFWGNDRLDDALDHCVQAPA

Sequences:

>Translated_201_residues
MSAAPIEFWFEFASNYSYLSVMRIEDCAARRGVQVRWKPFLLGPIFRSFGWQTSPFVLQKAKGDYVWQDMVRQCRKYDLA
WTRPSGFPRSSLLPSRVALVGAEQDWIGAYCRRVMSINFGEDREIDTNKVVTEVLTALGLPARQIIDEAQSEANKLRLRQ
QTETAARRGIFGAPMFFVGDDMFWGNDRLDDALDHCVQAPA
>Mature_200_residues
SAAPIEFWFEFASNYSYLSVMRIEDCAARRGVQVRWKPFLLGPIFRSFGWQTSPFVLQKAKGDYVWQDMVRQCRKYDLAW
TRPSGFPRSSLLPSRVALVGAEQDWIGAYCRRVMSINFGEDREIDTNKVVTEVLTALGLPARQIIDEAQSEANKLRLRQQ
TETAARRGIFGAPMFFVGDDMFWGNDRLDDALDHCVQAPA

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 22997; Mature: 22866

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAAPIEFWFEFASNYSYLSVMRIEDCAARRGVQVRWKPFLLGPIFRSFGWQTSPFVLQK
CCCCHHHHHHHHHCCCCEEEEEHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCHHEEC
AKGDYVWQDMVRQCRKYDLAWTRPSGFPRSSLLPSRVALVGAEQDWIGAYCRRVMSINFG
CCCCHHHHHHHHHHHHCCCCEECCCCCCCHHCCCHHHHEECCCHHHHHHHHHHHHHCCCC
EDREIDTNKVVTEVLTALGLPARQIIDEAQSEANKLRLRQQTETAARRGIFGAPMFFVGD
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECC
DMFWGNDRLDDALDHCVQAPA
CCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SAAPIEFWFEFASNYSYLSVMRIEDCAARRGVQVRWKPFLLGPIFRSFGWQTSPFVLQK
CCCHHHHHHHHHCCCCEEEEEHHHHHHHHCCCEEEECHHHHHHHHHHCCCCCCCHHEEC
AKGDYVWQDMVRQCRKYDLAWTRPSGFPRSSLLPSRVALVGAEQDWIGAYCRRVMSINFG
CCCCHHHHHHHHHHHHCCCCEECCCCCCCHHCCCHHHHEECCCHHHHHHHHHHHHHCCCC
EDREIDTNKVVTEVLTALGLPARQIIDEAQSEANKLRLRQQTETAARRGIFGAPMFFVGD
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEECC
DMFWGNDRLDDALDHCVQAPA
CCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226631 [H]