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The map label for this gene is glpE [C]

Identifier: 124265907

GI number: 124265907

Start: 742078

End: 742494

Strand: Direct

Name: glpE [C]

Synonym: Mpe_A0714

Alternate gene names: 124265907

Gene position: 742078-742494 (Clockwise)

Preceding gene: 124265905

Following gene: 124265908

Centisome position: 18.35

GC content: 70.98

Gene sequence:

>417_bases
GTGAAGTTTCTCCTCGACAACTGGTATCTGGTCCTCGCTGCGCTCGCCTCGGGCGGTCTTCTGGTCTGGCCGCTGATCGC
TCGCGGCGGCGGCCCGAACCGCGTGTCCACCGCCGAGGCGGTGATGCTGATCAACCGCGAGAAGGCGGTGCTGATCGACG
TGAGCGAGCCCGCCGAGTACGCCGCCGGCCATGCCAGCAACGCCCGCAACATCCCGCTCGCCGGTCTGGAGAGCGGCGCC
AAGGGCCTGCCCACCAACAAGAGCCTGCCGGTGCTGGTGATCTGCCCGACCGGCGCGCGCGCCAACCGCGCCGTCGCCAC
CCTGCGCAAGCTCGGCTACGAGAAGGCCAGCACCGTGATCGGCGGCCTGGCGGCCTGGCGCGAGGCGCAACTGCCGGTGG
AGAAGTCGGCGGCCTGA

Upstream 100 bases:

>100_bases
GGGTCATGAGGCGGGTCGCGGCAGCAATGGGAATAGCCGCAGATTCTAGAATCGCTGTCTTTCCGCCTCCCTGACCGCGC
TGGCCGCGCGCGCCCCCACC

Downstream 100 bases:

>100_bases
GCGGGCCCGGGCCTATCGACGAGATAGCGCCAAATGCCGCGCATTGCCGCGCAAATCAAACCCGCAGCCCGGCAAGGACG
TGTCGATTCCGTGACACTGG

Product: putative transmembrane protein

Products: H+; Sulfite; Thiocyanate [C]

Alternate protein names: Rhodanese Domain Protein; Rhodanese-Like Protein; Rhodanese-Related Sulfurtransferase; Transmembrane Protein; Rhodanese Domain-Containing Protein Sulfurtransferase; Thiosulfate Sulfurtransferase; SirA Family Protein; Rhodanese-Like Domain-Containing; Rhodanese-Like Domain Protein; Sulfurtransferase; Rhodanese-Related Sulfurtransferases; Rhodanese-Like Domain-Containing Protein; Sulphurtransferase; Sulfate Permease Andrelated Transporter; Rhodanese Sulfur Transferase; Rhodanese-Like Sulfurtransferase

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKFLLDNWYLVLAALASGGLLVWPLIARGGGPNRVSTAEAVMLINREKAVLIDVSEPAEYAAGHASNARNIPLAGLESGA
KGLPTNKSLPVLVICPTGARANRAVATLRKLGYEKASTVIGGLAAWREAQLPVEKSAA

Sequences:

>Translated_138_residues
MKFLLDNWYLVLAALASGGLLVWPLIARGGGPNRVSTAEAVMLINREKAVLIDVSEPAEYAAGHASNARNIPLAGLESGA
KGLPTNKSLPVLVICPTGARANRAVATLRKLGYEKASTVIGGLAAWREAQLPVEKSAA
>Mature_138_residues
MKFLLDNWYLVLAALASGGLLVWPLIARGGGPNRVSTAEAVMLINREKAVLIDVSEPAEYAAGHASNARNIPLAGLESGA
KGLPTNKSLPVLVICPTGARANRAVATLRKLGYEKASTVIGGLAAWREAQLPVEKSAA

Specific function: Catalyzes, Although With Low Efficiency, The Sulfur Transfer Reaction From Thiosulfate To Cyanide. The Relatively Low Affinity Of Glpe For Both Thiosulfate And Cyanide Suggests That These Compounds Are Not The Physiological Substrates. Thioredoxin 1 Or Re

COG id: COG0607

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.8.1.1 [C]

Molecular weight: Translated: 14399; Mature: 14399

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLLDNWYLVLAALASGGLLVWPLIARGGGPNRVSTAEAVMLINREKAVLIDVSEPAEY
CCEEHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCHHHEEEEECCCCEEEEECCCCHHH
AAGHASNARNIPLAGLESGAKGLPTNKSLPVLVICPTGARANRAVATLRKLGYEKASTVI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHH
GGLAAWREAQLPVEKSAA
HHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKFLLDNWYLVLAALASGGLLVWPLIARGGGPNRVSTAEAVMLINREKAVLIDVSEPAEY
CCEEHHHHHHHHHHHHCCCEEEEEHHHCCCCCCCCCHHHEEEEECCCCEEEEECCCCHHH
AAGHASNARNIPLAGLESGAKGLPTNKSLPVLVICPTGARANRAVATLRKLGYEKASTVI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHH
GGLAAWREAQLPVEKSAA
HHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cyanide; Thiosulfate [C]

Specific reaction: Cyanide + Thiosulfate --> H+ + Sulfite + Thiocyanate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA