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The map label for this gene is pyrR [H]

Identifier: 124265900

GI number: 124265900

Start: 736927

End: 737427

Strand: Direct

Name: pyrR [H]

Synonym: Mpe_A0707

Alternate gene names: 124265900

Gene position: 736927-737427 (Clockwise)

Preceding gene: 124265899

Following gene: 124265901

Centisome position: 18.22

GC content: 72.65

Gene sequence:

>501_bases
ATGACGACCCTGCACCTCGACGCGGAAGCGCTCTACGCCGATCTGCTGGCGCGGGTGCGGCCGCTGCTCAAGCCCGAGAC
CGTGCTGGTCGGCATCTGGTCGGGCGGCGCCTGGCTGGCCGAGCGGCTGCAGCGTGACCTGGGACTGGCCGGCCGCCACG
GCGTGATCTCGAGCGCGCTGCACCGAGACGACTTCGGCTCGCGCGGCATGAGCGCCACCACCGATGCGACGGCGCTGCCG
TTCGAGATCGAGGGCCGCCACATCCTGCTGATCGACGACGTGCTCTACACCGGCCGCACGGTGCGCGCGGTGATCAACGA
ACTGTTCGACTTCGGCCGCCCGGCCAGCGTCGGCCTCGCGGTGCTCGTCGACCGCGGCGGGCGCGAACTGCCGATCGAGC
CCGCCGTGTCGGCCGCCCGCGTGGTGGTGCCGCGCCACCAGCGGCTCGCGCTGGTGCGCGACGAGGCCGGCGGCTTCACA
CTCCAACTCGAAAGCGCCTGA

Upstream 100 bases:

>100_bases
ACGAGCGCTGGTCCACCACCGAGGCCCTGTCCGATGGGGCGCGCGACGCCGATGCCGCCGCCGCGGCGATCCTGCTCGAA
CAGTATTTCCAGGAGCACGC

Downstream 100 bases:

>100_bases
TGCTGAACAAGCGCAACCCGCAGCTCAACGCCCACGGCGAGCTGATCCACCTGCTGTCGATCGAAGGCCTGCCGAAGGCG
GTGCTGACGCAGATCCTCGA

Product: bifunctional regulator/uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTTLHLDAEALYADLLARVRPLLKPETVLVGIWSGGAWLAERLQRDLGLAGRHGVISSALHRDDFGSRGMSATTDATALP
FEIEGRHILLIDDVLYTGRTVRAVINELFDFGRPASVGLAVLVDRGGRELPIEPAVSAARVVVPRHQRLALVRDEAGGFT
LQLESA

Sequences:

>Translated_166_residues
MTTLHLDAEALYADLLARVRPLLKPETVLVGIWSGGAWLAERLQRDLGLAGRHGVISSALHRDDFGSRGMSATTDATALP
FEIEGRHILLIDDVLYTGRTVRAVINELFDFGRPASVGLAVLVDRGGRELPIEPAVSAARVVVPRHQRLALVRDEAGGFT
LQLESA
>Mature_165_residues
TTLHLDAEALYADLLARVRPLLKPETVLVGIWSGGAWLAERLQRDLGLAGRHGVISSALHRDDFGSRGMSATTDATALPF
EIEGRHILLIDDVLYTGRTVRAVINELFDFGRPASVGLAVLVDRGGRELPIEPAVSAARVVVPRHQRLALVRDEAGGFTL
QLESA

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 17969; Mature: 17838

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLHLDAEALYADLLARVRPLLKPETVLVGIWSGGAWLAERLQRDLGLAGRHGVISSAL
CCEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHH
HRDDFGSRGMSATTDATALPFEIEGRHILLIDDVLYTGRTVRAVINELFDFGRPASVGLA
HCCCCCCCCCCCCCCCEECCEEECCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCCCCEE
VLVDRGGRELPIEPAVSAARVVVPRHQRLALVRDEAGGFTLQLESA
EEEECCCCCCCCCCCCCHHEEECCCCCCEEEEEECCCCEEEEEECC
>Mature Secondary Structure 
TTLHLDAEALYADLLARVRPLLKPETVLVGIWSGGAWLAERLQRDLGLAGRHGVISSAL
CEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHH
HRDDFGSRGMSATTDATALPFEIEGRHILLIDDVLYTGRTVRAVINELFDFGRPASVGLA
HCCCCCCCCCCCCCCCEECCEEECCCEEEEECCHHHCCHHHHHHHHHHHHCCCCCCCCEE
VLVDRGGRELPIEPAVSAARVVVPRHQRLALVRDEAGGFTLQLESA
EEEECCCCCCCCCCCCCHHEEECCCCCCEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]