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The map label for this gene is fabD [H]

Identifier: 124265830

GI number: 124265830

Start: 672200

End: 673138

Strand: Direct

Name: fabD [H]

Synonym: Mpe_A0637

Alternate gene names: 124265830

Gene position: 672200-673138 (Clockwise)

Preceding gene: 124265829

Following gene: 124265831

Centisome position: 16.62

GC content: 71.88

Gene sequence:

>939_bases
ATGTCCGCATTCGCATTTGTCTTTCCCGGCCAGGGCTCCCAGACCGTCGGCATGCTCGACGCCTGGGGCGATCACCCGGT
CGTGGGCGAGACCCTGGCCGAAGCCTCGCAGGCGCTCGGCGAGGATCTGGTCGCGCTGATCCGGTCGGGTCCGAAGGAGG
CGCTGGACCTCACCTCGAACACCCAGCCGGTGATGCTCGCAGCCAGCATCGCCTGCTACCGTGCCTGGCTGGCCGAGACC
GGCCGGTCGCCGTCGATCGTGGCTGGGCACTCGCTGGGCGAGTACAGCGCCCTGGTGGCGGCCGGCGTGCTGAGCCTGGC
GGACGCGGTGCCGCTGGTCCGGCTGCGGGCGCAGGCGATGCAGGACGCGGTGCCGGTCGGCGCCGGCGCCATGGCGGCCA
TCCTCGGGCTGGACGCCGATGCGGTGCGCGCCGGGTGTGCCGACGCCGAGGCGGCGACCGGCGAGTCGGTGCAGGCGGCC
AACTACAACGACCCGAAGCAGACCGTGATCTCCGGCAGCAAGCTCGCCGTCGACAAGGCCTGCGAACTGCTGAAGGCGGC
CGGTGCCAAGCGGGCGCTCCCGCTGGCGGTGTCGGCACCTTTCCATTCGAGCCTGATGAAGCCGGCGGCCGAGCGGCTGC
GCCAGCGCCTTGTCGATGTGGCGCTGGCCGCGCCGGCCATTCCGGTGCTGAACAACATCGACGTCGCCGTCGAGTCCGAG
CCGGCGGCGATCCGCGACGCGCTCTACCGCCAGGCCTTCGGTCCGGTCCGCTGGGTCGAGACGGTGCAGGCGCTCAAGGC
CCGCGGTGTGTCGACCGTCGTGGAGTGCGGGCCGGGCAAGGTGCTGGCCGGGCTGGTGAAGCGGGTCGATGCCGAGCTGG
CCGTGCTGAACATCTTCGATCCGGCCAGCCTGGCCGAGACCCAAGGAGCCCTGGCATGA

Upstream 100 bases:

>100_bases
GGCGTGGGCGGCGGCTTCACCTGGGGCGCGGTGCTGCTCGACCTGTGATCGGCGCCGGGCCCGCCCGGCCAGAAGCCATA
AGAAGATTGGGAAGTTCTCG

Downstream 100 bases:

>100_bases
GCGCGGACGCTTCGGTGACGACGCAGGTGGCCCTGGTGACGGGCGCGAGCCGCGGCATCGGCCGCGCGATCGCGACCACG
CTGGCCGAGCGCGGCTTCAA

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSAFAFVFPGQGSQTVGMLDAWGDHPVVGETLAEASQALGEDLVALIRSGPKEALDLTSNTQPVMLAASIACYRAWLAET
GRSPSIVAGHSLGEYSALVAAGVLSLADAVPLVRLRAQAMQDAVPVGAGAMAAILGLDADAVRAGCADAEAATGESVQAA
NYNDPKQTVISGSKLAVDKACELLKAAGAKRALPLAVSAPFHSSLMKPAAERLRQRLVDVALAAPAIPVLNNIDVAVESE
PAAIRDALYRQAFGPVRWVETVQALKARGVSTVVECGPGKVLAGLVKRVDAELAVLNIFDPASLAETQGALA

Sequences:

>Translated_312_residues
MSAFAFVFPGQGSQTVGMLDAWGDHPVVGETLAEASQALGEDLVALIRSGPKEALDLTSNTQPVMLAASIACYRAWLAET
GRSPSIVAGHSLGEYSALVAAGVLSLADAVPLVRLRAQAMQDAVPVGAGAMAAILGLDADAVRAGCADAEAATGESVQAA
NYNDPKQTVISGSKLAVDKACELLKAAGAKRALPLAVSAPFHSSLMKPAAERLRQRLVDVALAAPAIPVLNNIDVAVESE
PAAIRDALYRQAFGPVRWVETVQALKARGVSTVVECGPGKVLAGLVKRVDAELAVLNIFDPASLAETQGALA
>Mature_311_residues
SAFAFVFPGQGSQTVGMLDAWGDHPVVGETLAEASQALGEDLVALIRSGPKEALDLTSNTQPVMLAASIACYRAWLAETG
RSPSIVAGHSLGEYSALVAAGVLSLADAVPLVRLRAQAMQDAVPVGAGAMAAILGLDADAVRAGCADAEAATGESVQAAN
YNDPKQTVISGSKLAVDKACELLKAAGAKRALPLAVSAPFHSSLMKPAAERLRQRLVDVALAAPAIPVLNNIDVAVESEP
AAIRDALYRQAFGPVRWVETVQALKARGVSTVVECGPGKVLAGLVKRVDAELAVLNIFDPASLAETQGALA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=33.003300330033, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=40.3669724770642, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1787334, Length=306, Percent_Identity=53.921568627451, Blast_Score=301, Evalue=5e-83,
Organism=Caenorhabditis elegans, GI71984332, Length=272, Percent_Identity=33.4558823529412, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17550940, Length=239, Percent_Identity=32.2175732217573, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=33.993399339934, Blast_Score=128, Evalue=4e-30,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31979; Mature: 31848

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFAFVFPGQGSQTVGMLDAWGDHPVVGETLAEASQALGEDLVALIRSGPKEALDLTSN
CCCEEEEECCCCCCEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
TQPVMLAASIACYRAWLAETGRSPSIVAGHSLGEYSALVAAGVLSLADAVPLVRLRAQAM
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAVPVGAGAMAAILGLDADAVRAGCADAEAATGESVQAANYNDPKQTVISGSKLAVDKA
HHHCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHCCCHHHHHHH
CELLKAAGAKRALPLAVSAPFHSSLMKPAAERLRQRLVDVALAAPAIPVLNNIDVAVESE
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCC
PAAIRDALYRQAFGPVRWVETVQALKARGVSTVVECGPGKVLAGLVKRVDAELAVLNIFD
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCEEEEEECC
PASLAETQGALA
CHHHHHHCCCCC
>Mature Secondary Structure 
SAFAFVFPGQGSQTVGMLDAWGDHPVVGETLAEASQALGEDLVALIRSGPKEALDLTSN
CCEEEEECCCCCCEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCC
TQPVMLAASIACYRAWLAETGRSPSIVAGHSLGEYSALVAAGVLSLADAVPLVRLRAQAM
CCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDAVPVGAGAMAAILGLDADAVRAGCADAEAATGESVQAANYNDPKQTVISGSKLAVDKA
HHHCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHCCCHHHHHHH
CELLKAAGAKRALPLAVSAPFHSSLMKPAAERLRQRLVDVALAAPAIPVLNNIDVAVESE
HHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEECCC
PAAIRDALYRQAFGPVRWVETVQALKARGVSTVVECGPGKVLAGLVKRVDAELAVLNIFD
CHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHCCCEEEEEECC
PASLAETQGALA
CHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]