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The map label for this gene is fabH [H]

Identifier: 124265829

GI number: 124265829

Start: 671149

End: 672147

Strand: Direct

Name: fabH [H]

Synonym: Mpe_A0636

Alternate gene names: 124265829

Gene position: 671149-672147 (Clockwise)

Preceding gene: 124265828

Following gene: 124265830

Centisome position: 16.6

GC content: 69.57

Gene sequence:

>999_bases
ATGACCCCCTCTGCCTCTTCCCTTCCTCGCTACGCGCGCATCACCGGCACCGGCAGCTACTTGCCGCCGCGTCGCCTGAC
CAACGCCCAACTCGCCGCCGAGCTGGCTCAGAGCGGCGTCGAGACCTCCGATGAATGGATCGTCGAGCGCACCGGTATCC
GCGCTCGCCACTTCGCGGCGACCGACGTCGCCTGCAGCGACCTGGCCGTCGAAGCCGCTCGCCATGCGCTCGAGGCAGCA
GGGCGGCAGGCGGCCGAAATCGACCTGATCATCGTGGCGACCTCCACGCCCGACATGGTCTTCCCCTCGACAGCCTGCAT
CGTGCAGCACAAGCTCGGTGTCGCCGGCTGCCCGGCCTTCGACCTGCAGGCGGTGTGTTCCGGCTTCGTCTATGCGCTGT
CGGTGGCCGATGCCATGATCCGCACGGGCGCCGCCAGCAGGGCGCTCGTGATCGGTGCCGAGGTGTTCTCCCGCATCCTC
GATTTCAAGGATCGCACCACCTGCGTGCTGTTCGGCGACGGTGCCGGTGCCGTGGTGCTGGAGGCCAGCGACACGCCGGG
CATCCTGGCGACCGAACTGCATGCCGACGGCAGCCATGTGGGCATCCTGTGCGTGCCGGGCACGGTCGCTGGCGGCCACG
TCACCGGCGATCCGCTGCTCAAGATGGACGGACAGGCGGTGTTCAAGCTCGCCGTCCGGGTGCTCGACGAGGCGGCGCGC
GCGGTGCTGGCCAAGGCCGGCCGCCAGGAGGCGGACGTCGACTGGCTGATTCCGCACCAAGCCAACATCCGCATCATGCA
GGGCACGGCCAAGAAGCTGAAGCTGCCGCTGGAGAAGCTGGTCGTGACCGTCGACGAGCACGGCAATACGTCGGCCGCCT
CGGTGCCGCTGGCGCTGGACCACGCGGTGCGCAGCGGCCGGGTCAAGCCGGGCGACACGGTGATGCTCGAAGGCGTGGGC
GGCGGCTTCACCTGGGGCGCGGTGCTGCTCGACCTGTGA

Upstream 100 bases:

>100_bases
GAAACCGACTGCTCGATCGGGTCCACGACCGCATCAGCGCGACGCTGCAGGCCCTGCCGGCCGATGCGGGCGCGCCGGAC
GGTCAGGTGCCCGAAGCCGC

Downstream 100 bases:

>100_bases
TCGGCGCCGGGCCCGCCCGGCCAGAAGCCATAAGAAGATTGGGAAGTTCTCGATGTCCGCATTCGCATTTGTCTTTCCCG
GCCAGGGCTCCCAGACCGTC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTPSASSLPRYARITGTGSYLPPRRLTNAQLAAELAQSGVETSDEWIVERTGIRARHFAATDVACSDLAVEAARHALEAA
GRQAAEIDLIIVATSTPDMVFPSTACIVQHKLGVAGCPAFDLQAVCSGFVYALSVADAMIRTGAASRALVIGAEVFSRIL
DFKDRTTCVLFGDGAGAVVLEASDTPGILATELHADGSHVGILCVPGTVAGGHVTGDPLLKMDGQAVFKLAVRVLDEAAR
AVLAKAGRQEADVDWLIPHQANIRIMQGTAKKLKLPLEKLVVTVDEHGNTSAASVPLALDHAVRSGRVKPGDTVMLEGVG
GGFTWGAVLLDL

Sequences:

>Translated_332_residues
MTPSASSLPRYARITGTGSYLPPRRLTNAQLAAELAQSGVETSDEWIVERTGIRARHFAATDVACSDLAVEAARHALEAA
GRQAAEIDLIIVATSTPDMVFPSTACIVQHKLGVAGCPAFDLQAVCSGFVYALSVADAMIRTGAASRALVIGAEVFSRIL
DFKDRTTCVLFGDGAGAVVLEASDTPGILATELHADGSHVGILCVPGTVAGGHVTGDPLLKMDGQAVFKLAVRVLDEAAR
AVLAKAGRQEADVDWLIPHQANIRIMQGTAKKLKLPLEKLVVTVDEHGNTSAASVPLALDHAVRSGRVKPGDTVMLEGVG
GGFTWGAVLLDL
>Mature_331_residues
TPSASSLPRYARITGTGSYLPPRRLTNAQLAAELAQSGVETSDEWIVERTGIRARHFAATDVACSDLAVEAARHALEAAG
RQAAEIDLIIVATSTPDMVFPSTACIVQHKLGVAGCPAFDLQAVCSGFVYALSVADAMIRTGAASRALVIGAEVFSRILD
FKDRTTCVLFGDGAGAVVLEASDTPGILATELHADGSHVGILCVPGTVAGGHVTGDPLLKMDGQAVFKLAVRVLDEAARA
VLAKAGRQEADVDWLIPHQANIRIMQGTAKKLKLPLEKLVVTVDEHGNTSAASVPLALDHAVRSGRVKPGDTVMLEGVGG
GFTWGAVLLDL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=320, Percent_Identity=51.875, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 34590; Mature: 34459

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSASSLPRYARITGTGSYLPPRRLTNAQLAAELAQSGVETSDEWIVERTGIRARHFAA
CCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEH
TDVACSDLAVEAARHALEAAGRQAAEIDLIIVATSTPDMVFPSTACIVQHKLGVAGCPAF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCHHHEEECCCCCCCCCCC
DLQAVCSGFVYALSVADAMIRTGAASRALVIGAEVFSRILDFKDRTTCVLFGDGAGAVVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEE
EASDTPGILATELHADGSHVGILCVPGTVAGGHVTGDPLLKMDGQAVFKLAVRVLDEAAR
ECCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
AVLAKAGRQEADVDWLIPHQANIRIMQGTAKKLKLPLEKLVVTVDEHGNTSAASVPLALD
HHHHHCCCCCCCCEEECCCCCCEEEEECCHHHHHCCHHHEEEEECCCCCCCCCCCCHHHH
HAVRSGRVKPGDTVMLEGVGGGFTWGAVLLDL
HHHHCCCCCCCCEEEEEECCCCEEEHEEEECC
>Mature Secondary Structure 
TPSASSLPRYARITGTGSYLPPRRLTNAQLAAELAQSGVETSDEWIVERTGIRARHFAA
CCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEH
TDVACSDLAVEAARHALEAAGRQAAEIDLIIVATSTPDMVFPSTACIVQHKLGVAGCPAF
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCHHHEEECCCCCCCCCCC
DLQAVCSGFVYALSVADAMIRTGAASRALVIGAEVFSRILDFKDRTTCVLFGDGAGAVVL
CHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEEEECCCCEEEE
EASDTPGILATELHADGSHVGILCVPGTVAGGHVTGDPLLKMDGQAVFKLAVRVLDEAAR
ECCCCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHH
AVLAKAGRQEADVDWLIPHQANIRIMQGTAKKLKLPLEKLVVTVDEHGNTSAASVPLALD
HHHHHCCCCCCCCEEECCCCCCEEEEECCHHHHHCCHHHEEEEECCCCCCCCCCCCHHHH
HAVRSGRVKPGDTVMLEGVGGGFTWGAVLLDL
HHHHCCCCCCCCEEEEEECCCCEEEHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA