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The map label for this gene is dapB [H]

Identifier: 124265414

GI number: 124265414

Start: 239289

End: 240119

Strand: Reverse

Name: dapB [H]

Synonym: Mpe_A0221

Alternate gene names: 124265414

Gene position: 240119-239289 (Counterclockwise)

Preceding gene: 124265415

Following gene: 124265413

Centisome position: 5.94

GC content: 70.4

Gene sequence:

>831_bases
GTGAAGGCGGTGGCCGCGGCTGAACGGCGCCGCATCGCGATCGCCGGTGCGTCGGGCCGCATGGGCCACATGCTGATCGA
GGCCGTGCTGGCCTCGGACGACTGCGTGCTGGCGGGCGCGCTCGACCGGCCCGACAGCCCCCAGCTCGGGCAGGATGCCG
CCGGTTTCCTCGGCCAGCGCAGCGGCGTGATGATCACCGACGACCTGCGTACCGGGCTCGCGAACGCCCAGGTCCTGATC
GACTTCACGCGCCCCGAGGGCACGCTGGCCCACCTGCAGGCCTGCCGCGAGCTCGGCGTGCAGCTGGTGATCGGCACCAC
CGGTTTCGACGAGGCCGGCAAGGCTCGCATCTCCGAGGCCGCGCAGCACATCGCCATCGTGATGGCGCCCAACATGAGCG
TGGGCGTGAATGTGGTTCTGCAGCTGCTGGCCACCGCTGCCAAGGCACTGAGCCAGGGCTACGACATCGAGATCATCGAG
GCCCACCACCGCCACAAGGTCGACGCCCCCAGCGGCACCGCGCTGAAGATGGGCGAAGTGGTGGCCGACGCGCTGGGCCG
CGATCTGAAGTCCTGCGCGGTCTACGGTCGCGAGGGCGTCACCGGTGAACGCGATCCGTCGACGATCGGCTTCGCCACCG
TGCGCGGCGGCGACATCGTCGGCGATCACACCGTGCTGTTCGCCGGCACTGGCGAGCGCATCGAGATCACGCACAAGTCC
AGCAGTCGCGCCACCTATGCCCAGGGCAGCCTGCGCGCGGTGCGTTTCCTCGCCGACCAGCAGCGCGGCCTCTACGGCAT
GGAGGCCGTTCTGGGCCTCGTGGCGACGTGA

Upstream 100 bases:

>100_bases
AGCTCAAGGCGCTGCCGATGCCCGCCAAGGGCAGCATCCCGGAGCCGAACAGCGCGCCGCAGGGCCCGGCCCGCGACTAC
CCGCCGCTGGAGGCGACGCC

Downstream 100 bases:

>100_bases
CCAGCGGTCTCGTGCACTTCTGGTCCGAGGGTGACGCGATCACCCGCCTCGTCGCCGCGCTGCTGTTGCTGATGTCGGTC
AGCGCGTGGGTGCTGATCTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MKAVAAAERRRIAIAGASGRMGHMLIEAVLASDDCVLAGALDRPDSPQLGQDAAGFLGQRSGVMITDDLRTGLANAQVLI
DFTRPEGTLAHLQACRELGVQLVIGTTGFDEAGKARISEAAQHIAIVMAPNMSVGVNVVLQLLATAAKALSQGYDIEIIE
AHHRHKVDAPSGTALKMGEVVADALGRDLKSCAVYGREGVTGERDPSTIGFATVRGGDIVGDHTVLFAGTGERIEITHKS
SSRATYAQGSLRAVRFLADQQRGLYGMEAVLGLVAT

Sequences:

>Translated_276_residues
MKAVAAAERRRIAIAGASGRMGHMLIEAVLASDDCVLAGALDRPDSPQLGQDAAGFLGQRSGVMITDDLRTGLANAQVLI
DFTRPEGTLAHLQACRELGVQLVIGTTGFDEAGKARISEAAQHIAIVMAPNMSVGVNVVLQLLATAAKALSQGYDIEIIE
AHHRHKVDAPSGTALKMGEVVADALGRDLKSCAVYGREGVTGERDPSTIGFATVRGGDIVGDHTVLFAGTGERIEITHKS
SSRATYAQGSLRAVRFLADQQRGLYGMEAVLGLVAT
>Mature_276_residues
MKAVAAAERRRIAIAGASGRMGHMLIEAVLASDDCVLAGALDRPDSPQLGQDAAGFLGQRSGVMITDDLRTGLANAQVLI
DFTRPEGTLAHLQACRELGVQLVIGTTGFDEAGKARISEAAQHIAIVMAPNMSVGVNVVLQLLATAAKALSQGYDIEIIE
AHHRHKVDAPSGTALKMGEVVADALGRDLKSCAVYGREGVTGERDPSTIGFATVRGGDIVGDHTVLFAGTGERIEITHKS
SSRATYAQGSLRAVRFLADQQRGLYGMEAVLGLVAT

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=59.8484848484849, Blast_Score=285, Evalue=3e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28867; Mature: 28867

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVAAAERRRIAIAGASGRMGHMLIEAVLASDDCVLAGALDRPDSPQLGQDAAGFLGQR
CCCCHHHCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCCC
SGVMITDDLRTGLANAQVLIDFTRPEGTLAHLQACRELGVQLVIGTTGFDEAGKARISEA
CCEEEEHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHH
AQHIAIVMAPNMSVGVNVVLQLLATAAKALSQGYDIEIIEAHHRHKVDAPSGTALKMGEV
HHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEHHHHH
VADALGRDLKSCAVYGREGVTGERDPSTIGFATVRGGDIVGDHTVLFAGTGERIEITHKS
HHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEEEECC
SSRATYAQGSLRAVRFLADQQRGLYGMEAVLGLVAT
CCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MKAVAAAERRRIAIAGASGRMGHMLIEAVLASDDCVLAGALDRPDSPQLGQDAAGFLGQR
CCCCHHHCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHCCC
SGVMITDDLRTGLANAQVLIDFTRPEGTLAHLQACRELGVQLVIGTTGFDEAGKARISEA
CCEEEEHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHH
AQHIAIVMAPNMSVGVNVVLQLLATAAKALSQGYDIEIIEAHHRHKVDAPSGTALKMGEV
HHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEHHHHH
VADALGRDLKSCAVYGREGVTGERDPSTIGFATVRGGDIVGDHTVLFAGTGERIEITHKS
HHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEEEECC
SSRATYAQGSLRAVRFLADQQRGLYGMEAVLGLVAT
CCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA