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The map label for this gene is nahD [H]

Identifier: 124265293

GI number: 124265293

Start: 95876

End: 96481

Strand: Reverse

Name: nahD [H]

Synonym: Mpe_A0100

Alternate gene names: 124265293

Gene position: 96481-95876 (Counterclockwise)

Preceding gene: 124265294

Following gene: 124265292

Centisome position: 2.39

GC content: 70.13

Gene sequence:

>606_bases
ATGCGCCCCACCATCGATTACTACCTGGCGCCGCAGTCGCCGTACACCTACCTCGGCCACCTGCGCTTCTGGGACATCGC
CCGCAAGGCCGGCGCAACGATCCGCGTGATGCCCGTCGACCTGGGGGGCAAGGTGTTCCCGGTGTCGGGCGGCCTGCCGC
TGGGCAAGCGCGCGCCACAGCGCCAGGCGTACCGGCTGGTGGAGCTCAAGCGCTTCAGCGAGTGGCTGCACGCCCCGCTG
AACCTCGAACCCAAGTACTTCCCGGTCAACGGCGACGACGCCGCACGGCTGATCATCGCGGTCGACCTGCACGACGGCGC
CGATGCCGCAATGGCCATCGCCGACAGCATCCTGCGCGCGGTGTGGGTCCACGACCGCAACATCGCCGACGAAGCGGTGC
TCGCATCGCTGCTGGTCGAGCGCGAGCTGCCGGCCGCGCGGCTCGAGGCCGCGCACTCGCAGGCGGTGCAGGAGCGTTAC
GAGGCCGATTCGCAGGCGGCGGTCGATGCCGGGGTGTTCGGCGCGCCGAGCTACGTGGTGCAGGGTGAGATCTTCTGGGG
CCAGGACCGGCTCGATTTCCTCGAACGGCGCCTGAAGGCCGGCTGA

Upstream 100 bases:

>100_bases
AGGGCCACTCCCGTACGCCGCCGCACCGATTGCGGGCAGCCTCTAGACTCGCTGCACAGGCGCCCGAGCGCCGGCCCATC
CCCACGCGAGCGGAGACCCC

Downstream 100 bases:

>100_bases
ACGCGGCACCGCCGGCCGGCGGTCGAGGCCGCGGCGGCAACGCCACAATACGCGGGCCCGCCCCCCGCGACACCATGCCG
ATCCCCTTCCACCCCCGAGA

Product: 2-hydroxychromene-2-carboxylate isomerase

Products: NA

Alternate protein names: HCCA isomerase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRPTIDYYLAPQSPYTYLGHLRFWDIARKAGATIRVMPVDLGGKVFPVSGGLPLGKRAPQRQAYRLVELKRFSEWLHAPL
NLEPKYFPVNGDDAARLIIAVDLHDGADAAMAIADSILRAVWVHDRNIADEAVLASLLVERELPAARLEAAHSQAVQERY
EADSQAAVDAGVFGAPSYVVQGEIFWGQDRLDFLERRLKAG

Sequences:

>Translated_201_residues
MRPTIDYYLAPQSPYTYLGHLRFWDIARKAGATIRVMPVDLGGKVFPVSGGLPLGKRAPQRQAYRLVELKRFSEWLHAPL
NLEPKYFPVNGDDAARLIIAVDLHDGADAAMAIADSILRAVWVHDRNIADEAVLASLLVERELPAARLEAAHSQAVQERY
EADSQAAVDAGVFGAPSYVVQGEIFWGQDRLDFLERRLKAG
>Mature_201_residues
MRPTIDYYLAPQSPYTYLGHLRFWDIARKAGATIRVMPVDLGGKVFPVSGGLPLGKRAPQRQAYRLVELKRFSEWLHAPL
NLEPKYFPVNGDDAARLIIAVDLHDGADAAMAIADSILRAVWVHDRNIADEAVLASLLVERELPAARLEAAHSQAVQERY
EADSQAAVDAGVFGAPSYVVQGEIFWGQDRLDFLERRLKAG

Specific function: Catalyzes the isomerization of 2-hydroxychromene-2- carboxylate (HCCA) to trans-O-hydroxybenzylidenepyruvate (THBPA). The reaction is reversible [H]

COG id: COG3917

COG function: function code Q; 2-hydroxychromene-2-carboxylate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR014440
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA [H]

EC number: NA

Molecular weight: Translated: 22307; Mature: 22307

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPTIDYYLAPQSPYTYLGHLRFWDIARKAGATIRVMPVDLGGKVFPVSGGLPLGKRAPQ
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCCH
RQAYRLVELKRFSEWLHAPLNLEPKYFPVNGDDAARLIIAVDLHDGADAAMAIADSILRA
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
VWVHDRNIADEAVLASLLVERELPAARLEAAHSQAVQERYEADSQAAVDAGVFGAPSYVV
HHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEE
QGEIFWGQDRLDFLERRLKAG
EEEEEECCHHHHHHHHHHCCC
>Mature Secondary Structure
MRPTIDYYLAPQSPYTYLGHLRFWDIARKAGATIRVMPVDLGGKVFPVSGGLPLGKRAPQ
CCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEECCCCCCCCCCCH
RQAYRLVELKRFSEWLHAPLNLEPKYFPVNGDDAARLIIAVDLHDGADAAMAIADSILRA
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHH
VWVHDRNIADEAVLASLLVERELPAARLEAAHSQAVQERYEADSQAAVDAGVFGAPSYVV
HHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEE
QGEIFWGQDRLDFLERRLKAG
EEEEEECCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002605; 1447127 [H]