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The map label for this gene is livH [H]

Identifier: 124024661

GI number: 124024661

Start: 2626706

End: 2627860

Strand: Reverse

Name: livH [H]

Synonym: P9303_29731

Alternate gene names: 124024661

Gene position: 2627860-2626706 (Counterclockwise)

Preceding gene: 124024662

Following gene: 124024660

Centisome position: 97.96

GC content: 56.28

Gene sequence:

>1155_bases
GTGCAACTGCTTCTTGAAAGTCTTTTCAATGGTGTGGCCATCGGCTCGGTGCTGCTGGTTGCTGCCCTCGGACTGGCGAT
AGTCTTCGGCCTGATGGGTGTCATTAACCTCGCCCATGGCGAGTTGATCATGCTCGGGGCCTACACCACTTATGTGGTAC
AGCTGATCTTCAAGCTGCCTGCTTTGCAGCCTGTCTACAACGCTTATGTGTTGGTGGCGATTCCTCTGGCCTTCATCGTT
AGTGGTGTGGTTGGTATCTTGCTAGAACGCACCGTGATTCGTCGTCTCTACGGCAACCCGTTGGAGACATTGTTGGCGAC
ATGGGGCGTCAGCCTGATTCTGCAGCAGTTTGTGCGCAGTGTTCCATTGGCTTATGCGGCTGGCTTGGTGCTGGCGTTAG
TGCTTGGCTTTAGTCTGCCGATCATTCTTCCTGACAAGCTTTTGCAGGGGCCGCGGGCCCGCCTGGTGCGTGCTGGAAGC
TGGCTTGTGTCGGCTCTGGCTGGGGTGTTACTGGCGGGTGGCTTGGCCTCTCAGATCAGTCGTATCGCTCGTGCGACCTC
TCGCAATGTCGATGTCACGGCACCTAAGTGGATGCGTGGGGGGATTGAACTGTCGGGCATGACCTTCCCTGTGCCACGCT
TAGTGATCATTGTGATCACGATCCTCGCTGTACTCGGTATCACCTGGTTCTTGAATCGCAGTGTGTGGGGGATGCGCATC
AGGGCAGTGACTCAGAATCGCTCCATGAGTGATTGCCTTGGTATCTCAACCGATACCGTGGATGTGCTTACCTTTGGTAT
CGGCTCCGGTTTGGCTGGCATCGCGGGGGTAGCGGTGTCTCTGTTGGGATCCGTGGGACCCAACGTCGGCACTTCTTATA
TCGTTGGTTGCTTCATGGTGGTGGTGCTTGGCGGCGTGGGAAATCTGTTCGGCACCGTGTTGGCCTCCTTTGCTATTGGG
GTGCTAACAGACCTGATCGGTGCTGGCCGTTTGCTCAGTATCTGGCCTTCGATGCCTGCGCCTTTGGCGAGCGTGGTTGA
TTTTTTTGCTACCACGAGCATGGCCCAGGTGATGGTCTTTGCGCTGATTGTGGTGTTCCTTCAGTTCCGTCCTGCTGGTC
TGTTTCCCCAGAGGGGACGCATGGTGGAGGCTTAA

Upstream 100 bases:

>100_bases
GATTACCTTGTCAAGGCGTTTTTCCGCTTTGGCATTGTTTGGGAGGAGTCCGGAAACGGGCTCCTCCTTTCGTCGTTTTT
CCGGTCTCTGATCTTCGCCC

Downstream 100 bases:

>100_bases
ATCAATGTTGAAAGCGTTTCAACAACGCCGTTGGCCCCTGGTGATTGTCTGGGTCTTGATCATTGCTGCGATTGTGGCGG
CGCCTGCAGTGGTGTCGGTA

Product: urea ABC transporter

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQLLLESLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELIMLGAYTTYVVQLIFKLPALQPVYNAYVLVAIPLAFIV
SGVVGILLERTVIRRLYGNPLETLLATWGVSLILQQFVRSVPLAYAAGLVLALVLGFSLPIILPDKLLQGPRARLVRAGS
WLVSALAGVLLAGGLASQISRIARATSRNVDVTAPKWMRGGIELSGMTFPVPRLVIIVITILAVLGITWFLNRSVWGMRI
RAVTQNRSMSDCLGISTDTVDVLTFGIGSGLAGIAGVAVSLLGSVGPNVGTSYIVGCFMVVVLGGVGNLFGTVLASFAIG
VLTDLIGAGRLLSIWPSMPAPLASVVDFFATTSMAQVMVFALIVVFLQFRPAGLFPQRGRMVEA

Sequences:

>Translated_384_residues
MQLLLESLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELIMLGAYTTYVVQLIFKLPALQPVYNAYVLVAIPLAFIV
SGVVGILLERTVIRRLYGNPLETLLATWGVSLILQQFVRSVPLAYAAGLVLALVLGFSLPIILPDKLLQGPRARLVRAGS
WLVSALAGVLLAGGLASQISRIARATSRNVDVTAPKWMRGGIELSGMTFPVPRLVIIVITILAVLGITWFLNRSVWGMRI
RAVTQNRSMSDCLGISTDTVDVLTFGIGSGLAGIAGVAVSLLGSVGPNVGTSYIVGCFMVVVLGGVGNLFGTVLASFAIG
VLTDLIGAGRLLSIWPSMPAPLASVVDFFATTSMAQVMVFALIVVFLQFRPAGLFPQRGRMVEA
>Mature_384_residues
MQLLLESLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELIMLGAYTTYVVQLIFKLPALQPVYNAYVLVAIPLAFIV
SGVVGILLERTVIRRLYGNPLETLLATWGVSLILQQFVRSVPLAYAAGLVLALVLGFSLPIILPDKLLQGPRARLVRAGS
WLVSALAGVLLAGGLASQISRIARATSRNVDVTAPKWMRGGIELSGMTFPVPRLVIIVITILAVLGITWFLNRSVWGMRI
RAVTQNRSMSDCLGISTDTVDVLTFGIGSGLAGIAGVAVSLLGSVGPNVGTSYIVGCFMVVVLGGVGNLFGTVLASFAIG
VLTDLIGAGRLLSIWPSMPAPLASVVDFFATTSMAQVMVFALIVVFLQFRPAGLFPQRGRMVEA

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 40428; Mature: 40428

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLLESLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELIMLGAYTTYVVQLIFKLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCC
ALQPVYNAYVLVAIPLAFIVSGVVGILLERTVIRRLYGNPLETLLATWGVSLILQQFVRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VPLAYAAGLVLALVLGFSLPIILPDKLLQGPRARLVRAGSWLVSALAGVLLAGGLASQIS
CHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RIARATSRNVDVTAPKWMRGGIELSGMTFPVPRLVIIVITILAVLGITWFLNRSVWGMRI
HHHHHHCCCCCCCCCHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHEE
RAVTQNRSMSDCLGISTDTVDVLTFGIGSGLAGIAGVAVSLLGSVGPNVGTSYIVGCFMV
EEHHCCCCHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VVLGGVGNLFGTVLASFAIGVLTDLIGAGRLLSIWPSMPAPLASVVDFFATTSMAQVMVF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALIVVFLQFRPAGLFPQRGRMVEA
HHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQLLLESLFNGVAIGSVLLVAALGLAIVFGLMGVINLAHGELIMLGAYTTYVVQLIFKLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCC
ALQPVYNAYVLVAIPLAFIVSGVVGILLERTVIRRLYGNPLETLLATWGVSLILQQFVRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VPLAYAAGLVLALVLGFSLPIILPDKLLQGPRARLVRAGSWLVSALAGVLLAGGLASQIS
CHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RIARATSRNVDVTAPKWMRGGIELSGMTFPVPRLVIIVITILAVLGITWFLNRSVWGMRI
HHHHHHCCCCCCCCCHHHHCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHEE
RAVTQNRSMSDCLGISTDTVDVLTFGIGSGLAGIAGVAVSLLGSVGPNVGTSYIVGCFMV
EEHHCCCCHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
VVLGGVGNLFGTVLASFAIGVLTDLIGAGRLLSIWPSMPAPLASVVDFFATTSMAQVMVF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ALIVVFLQFRPAGLFPQRGRMVEA
HHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]