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The map label for this gene is menC [H]

Identifier: 124024421

GI number: 124024421

Start: 2407407

End: 2408375

Strand: Reverse

Name: menC [H]

Synonym: P9303_27331

Alternate gene names: 124024421

Gene position: 2408375-2407407 (Counterclockwise)

Preceding gene: 124024422

Following gene: 124024420

Centisome position: 89.78

GC content: 59.03

Gene sequence:

>969_bases
ATGGCTCTCAAGTTTCAGTGCAAACCGTTTTCATTTCGTTTGAGTCGGGTGTTGCAGACGGCTCAGGGGGTTGTTGAAGA
ACGGCAGGGTTGGTTGCTGAGATTGGAGGATGCCGCGGGTCGTTGTGGTTGGGGGGAGGTGGCTCCGATGGATGCGGCTG
GTTTAAAGGCCTGCGGAGATTGTTTGGTCAAGCTGCGCTTGGCACCAACGCGTTTGGAGTTGGAGGATGGAATGGCGTTT
TGGCCTGCGCCTTTGGCTTTTGGCGTGGGTGCAGCTCTGGCGGAATTGGATGGCCTCGTGGGGTCTGTGACAACAGGCGG
TTGGCTTGCGGCGCCTGCCTCTGCTGTGTTGTTGCCGGCGGGGCAGGCTCTTTTGAAGGCTTTGGATTCCATGCTTGAGA
TGGATCCCTCAGCCGCTGATCCCTTCACCGTGAAGTGGAAGGTGGCCGTCGCTCCAGATGCACTGGAGCGGCGCCTCTTG
TTGCAATTGTTGGAGCGGCTGCCAGACCATGCGCGCTTCAGGCTTGATGGCAATGGCGGTTGGGATCGCAGTGTGGTCAG
CTGGTGGGTGGAGCGATGTCTGCAGGATCCGAGGCTGGAATGGTTGGAACAACCTTTGCCTGCTAGTGATCTTGAGGGGT
TAAGAGCTTTGGCTCAACAGGTTCCTGTGGCTCTTGATGAGTCGCTTGTGCTTGAGCCATCACTGCGAGAGTCATGGTCT
GGCTGGCAGGTGCGGCGTCCGCTCTTAGACGGTGATCCAAGACCTCTGCTGAGGGTGCTGCAGGAGGGTGTGGGCTACCG
GATGTTGAGCACGGCCTTTGAAACCGGCATTGGTCGGCGTTGGCTCCACCATCTCGCTGCTTTGCAGCATCAGGGCCCTA
CACCAGTGGCTCCTGGCCTGGCCCCGGGTTGGTGCCCTGATGGACCTTTATTTAGCGCTGATCCCGAAGTGGTCTGGGCG
GCGGCATGA

Upstream 100 bases:

>100_bases
TTGGCATTGCGCTTTCAGGCGCTCAATGGCTTGGGGTTGAGCTTGGGCCTAGCGCTAGCGCCTTACTTGGGCTTTGCGAT
GTCTAGCGCAGGTTGAGTTG

Downstream 100 bases:

>100_bases
GGGGGTTGGTTGCCCTGCGTTGCAATCCCGCTCAGGCTGAGCAAAGGGCCTTGCAGCTTGCTCAGGCCTTGGAGCAAGGC
GATTGGGTGCAACTGCTGCC

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MALKFQCKPFSFRLSRVLQTAQGVVEERQGWLLRLEDAAGRCGWGEVAPMDAAGLKACGDCLVKLRLAPTRLELEDGMAF
WPAPLAFGVGAALAELDGLVGSVTTGGWLAAPASAVLLPAGQALLKALDSMLEMDPSAADPFTVKWKVAVAPDALERRLL
LQLLERLPDHARFRLDGNGGWDRSVVSWWVERCLQDPRLEWLEQPLPASDLEGLRALAQQVPVALDESLVLEPSLRESWS
GWQVRRPLLDGDPRPLLRVLQEGVGYRMLSTAFETGIGRRWLHHLAALQHQGPTPVAPGLAPGWCPDGPLFSADPEVVWA
AA

Sequences:

>Translated_322_residues
MALKFQCKPFSFRLSRVLQTAQGVVEERQGWLLRLEDAAGRCGWGEVAPMDAAGLKACGDCLVKLRLAPTRLELEDGMAF
WPAPLAFGVGAALAELDGLVGSVTTGGWLAAPASAVLLPAGQALLKALDSMLEMDPSAADPFTVKWKVAVAPDALERRLL
LQLLERLPDHARFRLDGNGGWDRSVVSWWVERCLQDPRLEWLEQPLPASDLEGLRALAQQVPVALDESLVLEPSLRESWS
GWQVRRPLLDGDPRPLLRVLQEGVGYRMLSTAFETGIGRRWLHHLAALQHQGPTPVAPGLAPGWCPDGPLFSADPEVVWA
AA
>Mature_321_residues
ALKFQCKPFSFRLSRVLQTAQGVVEERQGWLLRLEDAAGRCGWGEVAPMDAAGLKACGDCLVKLRLAPTRLELEDGMAFW
PAPLAFGVGAALAELDGLVGSVTTGGWLAAPASAVLLPAGQALLKALDSMLEMDPSAADPFTVKWKVAVAPDALERRLLL
QLLERLPDHARFRLDGNGGWDRSVVSWWVERCLQDPRLEWLEQPLPASDLEGLRALAQQVPVALDESLVLEPSLRESWSG
WQVRRPLLDGDPRPLLRVLQEGVGYRMLSTAFETGIGRRWLHHLAALQHQGPTPVAPGLAPGWCPDGPLFSADPEVVWAA
A

Specific function: Converts SHCHC to OSB [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 35089; Mature: 34958

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKFQCKPFSFRLSRVLQTAQGVVEERQGWLLRLEDAAGRCGWGEVAPMDAAGLKACGD
CCCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
CLVKLRLAPTRLELEDGMAFWPAPLAFGVGAALAELDGLVGSVTTGGWLAAPASAVLLPA
HHHHHCCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEECC
GQALLKALDSMLEMDPSAADPFTVKWKVAVAPDALERRLLLQLLERLPDHARFRLDGNGG
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEECCCCC
WDRSVVSWWVERCLQDPRLEWLEQPLPASDLEGLRALAQQVPVALDESLVLEPSLRESWS
CCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCEEECCCHHHCCC
GWQVRRPLLDGDPRPLLRVLQEGVGYRMLSTAFETGIGRRWLHHLAALQHQGPTPVAPGL
CCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCC
APGWCPDGPLFSADPEVVWAAA
CCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure 
ALKFQCKPFSFRLSRVLQTAQGVVEERQGWLLRLEDAAGRCGWGEVAPMDAAGLKACGD
CCEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHH
CLVKLRLAPTRLELEDGMAFWPAPLAFGVGAALAELDGLVGSVTTGGWLAAPASAVLLPA
HHHHHCCCCCEEECCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEECC
GQALLKALDSMLEMDPSAADPFTVKWKVAVAPDALERRLLLQLLERLPDHARFRLDGNGG
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEECCCCC
WDRSVVSWWVERCLQDPRLEWLEQPLPASDLEGLRALAQQVPVALDESLVLEPSLRESWS
CCHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHCCCHHCCCEEECCCHHHCCC
GWQVRRPLLDGDPRPLLRVLQEGVGYRMLSTAFETGIGRRWLHHLAALQHQGPTPVAPGL
CCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCC
APGWCPDGPLFSADPEVVWAAA
CCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]