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The map label for this gene is dltR [H]

Identifier: 124024406

GI number: 124024406

Start: 2395971

End: 2396672

Strand: Reverse

Name: dltR [H]

Synonym: P9303_27181

Alternate gene names: 124024406

Gene position: 2396672-2395971 (Counterclockwise)

Preceding gene: 124024407

Following gene: 124024405

Centisome position: 89.34

GC content: 54.56

Gene sequence:

>702_bases
GTGGAGGCTGCCCCGTCTCCGCGGTTACTACTGGTTGATGATGAACCCGGACTGCGCACTGCGGTGCAGGCTTATCTGGA
GGATGAAGGATTTGAGGTCACCACTGCTGTCGATGGAGACGATGGCTGGCAGAAGGCTCAAGAGATGCTGCCTGATTTGG
TCATCAGCGATGTGATGATGCCGCGTTGTGATGGCTATGGACTGCTTAAGCGCATGCGGGAGGACGAGCGCTTGGGTGGC
ACTCCTGTGATTTTTCTCACTGCTAAGGGGATGACGGCCGATCGCACCGAGGGTTATTTGGCTGGGGTGGATGACTACAT
CCCTAAACCCTTTGACCCTGAGGAGTTGGTGGCTCGTGTCCGCAACGTGGTTCGTCGGCAAGATCGTCTTCTTCGGGAAG
CAGCTCGTTTCGCGGATACTGATGTGGGTCAGATGGCCCGCCAGATCACAGAGATTCGCACCATGCTTGCCCATGGTGAT
GGTAGTTCATCCAAGGATGTAGCGCTTCACAATTTCACGCCGCGGGAGGCGAGTGTTCTGCAATTGGTGGCTGAGGGGTT
GATGAATAAGGAGATCGCTCGGCAGTTGGAGACATCAATTCGCAATGTTGAGAAGTACGTGAGTCGTCTGTTCATCAAAA
CGGGCACGTCAAGTCGCACTGAGTTGGTTCGTTATGCCTTGGAAAACCAGTTGGTGACATGA

Upstream 100 bases:

>100_bases
CGTTGAGGTCCCTATCGCTTCAAGACTGTTGGGGCGATCGCTTCTAGATTTTTGCAGCTTGCAATCCTGTTGGCCCATGA
GTGAGACCCTTCCCCAGAAT

Downstream 100 bases:

>100_bases
CCATTGGCAGGCTGCAATGGCGTGTCTGATGCGGATTGGCTCTCAGCCAGCTTCAACCATGGCTGGACCTACAGCCAACG
CATTGCTGCTGTGGATGCTG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MEAAPSPRLLLVDDEPGLRTAVQAYLEDEGFEVTTAVDGDDGWQKAQEMLPDLVISDVMMPRCDGYGLLKRMREDERLGG
TPVIFLTAKGMTADRTEGYLAGVDDYIPKPFDPEELVARVRNVVRRQDRLLREAARFADTDVGQMARQITEIRTMLAHGD
GSSSKDVALHNFTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENQLVT

Sequences:

>Translated_233_residues
MEAAPSPRLLLVDDEPGLRTAVQAYLEDEGFEVTTAVDGDDGWQKAQEMLPDLVISDVMMPRCDGYGLLKRMREDERLGG
TPVIFLTAKGMTADRTEGYLAGVDDYIPKPFDPEELVARVRNVVRRQDRLLREAARFADTDVGQMARQITEIRTMLAHGD
GSSSKDVALHNFTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENQLVT
>Mature_233_residues
MEAAPSPRLLLVDDEPGLRTAVQAYLEDEGFEVTTAVDGDDGWQKAQEMLPDLVISDVMMPRCDGYGLLKRMREDERLGG
TPVIFLTAKGMTADRTEGYLAGVDDYIPKPFDPEELVARVRNVVRRQDRLLREAARFADTDVGQMARQITEIRTMLAHGD
GSSSKDVALHNFTPREASVLQLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENQLVT

Specific function: Member of the two-component regulatory system dltS/dltR. Regulates the expression of the dlt operon [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=41.1764705882353, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1789809, Length=120, Percent_Identity=39.1666666666667, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI2367329, Length=119, Percent_Identity=44.5378151260504, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788394, Length=121, Percent_Identity=38.0165289256198, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786784, Length=170, Percent_Identity=32.9411764705882, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790860, Length=149, Percent_Identity=34.8993288590604, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790863, Length=121, Percent_Identity=36.3636363636364, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787375, Length=123, Percent_Identity=34.9593495934959, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082012, Length=123, Percent_Identity=35.7723577235772, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=35.8333333333333, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787229, Length=126, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=187, Percent_Identity=28.3422459893048, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786911, Length=143, Percent_Identity=33.5664335664336, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788905, Length=207, Percent_Identity=28.0193236714976, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790552, Length=121, Percent_Identity=31.404958677686, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787473, Length=218, Percent_Identity=30.2752293577982, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=213, Percent_Identity=25.8215962441315, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788521, Length=222, Percent_Identity=29.7297297297297, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26090; Mature: 26090

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAAPSPRLLLVDDEPGLRTAVQAYLEDEGFEVTTAVDGDDGWQKAQEMLPDLVISDVMM
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
PRCDGYGLLKRMREDERLGGTPVIFLTAKGMTADRTEGYLAGVDDYIPKPFDPEELVARV
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCHHHCCCCCCHHHHHHHH
RNVVRRQDRLLREAARFADTDVGQMARQITEIRTMLAHGDGSSSKDVALHNFTPREASVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHH
QLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENQLVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEAAPSPRLLLVDDEPGLRTAVQAYLEDEGFEVTTAVDGDDGWQKAQEMLPDLVISDVMM
CCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
PRCDGYGLLKRMREDERLGGTPVIFLTAKGMTADRTEGYLAGVDDYIPKPFDPEELVARV
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEECCHHHCCCCCCHHHHHHHH
RNVVRRQDRLLREAARFADTDVGQMARQITEIRTMLAHGDGSSSKDVALHNFTPREASVL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHH
QLVAEGLMNKEIARQLETSIRNVEKYVSRLFIKTGTSSRTELVRYALENQLVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11591677; 12354221 [H]