| Definition | Prochlorococcus marinus str. MIT 9303, complete genome. |
|---|---|
| Accession | NC_008820 |
| Length | 2,682,675 |
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The map label for this gene is glmS [H]
Identifier: 124024292
GI number: 124024292
Start: 2297138
End: 2299042
Strand: Reverse
Name: glmS [H]
Synonym: P9303_26041
Alternate gene names: 124024292
Gene position: 2299042-2297138 (Counterclockwise)
Preceding gene: 124024293
Following gene: 124024289
Centisome position: 85.7
GC content: 54.86
Gene sequence:
>1905_bases ATGTGCGGAATCGTTGCGGTTATTGGCTCCCGTGAGGCGGCCCCGTTGCTGTTAGAAGGGCTTAGGCAGCTCGAATACCG CGGTTACGACTCTGCTGGTCTTGCCACTGTTGAGCTGTTAGCTGAGGATGGTTCCAGTCGGCTCACCTGCCAGCGGGCTC AAGGAAAGCTGGTAAACCTCACAGCATGTGTGGAAGAGAAGGGTGCGCCAGGGCATTGCGGCATCGGCCACACCCGTTGG GCCACCCATGGCAAACCTGAAGAGCGCAATGCTCATCCGCATAGGGATGGCTCTGGTCTTGTGGCGGTAGTGCAGAACGG CATTATCGAGAATCACCGTTCTCTCCGCGAGGCACTTGAGGCTGAAGGGGTGAGGTTTGTTTCAGAGACAGATACGGAAG TCATTCCTCATCTCATCTCGCTTGAACTTCGTGCTCTGCAGGTTCAGGGCCGAGTCGTGAATGGAAGGATGTTGTTAGAG GCTGTGCAACGGGTGTTGCCTCAGTTGAAGGGCGCCTATGCCCTGGCAGTGGTTTGGGGGGAAGTGCCAGGTGCTCTTGT CGTCGCACGCAAGCAGGCACCGCTGTTGATTGGTCTTGGCGAAGGTGAATTCCTCTGCGCAAGTGATACGCCAGCTTTGG CAGGCTTCACGCGCACGATTCTTCCTATGGAAGATGGAGAGGTGGCCTTGCTCACCCCTTTGGGGATTGAGCTTTATGAC GCACAAGGCGAACGGCAGCAGCGAAGCCCTTCACTGCTCAGTGGCGGTGATCAAGTGGCCGATAAACGTCACTTCCGTCA TTTCATGCTGAAGGAAATCCACGAGCAGCCTGAGACTGCGGAGCTGTGGGTAGCACGTCATTTGCCTCCAGATCTTTCGT CTGATGATCCTGTGGCTTTGCCCTTCGATCATTCCTTTTATGCCGATCTAGAGCGAATTCAGATTTTGGCCTGTGGCACG AGTCGTCATGCGGCACTTGTAGGGGCCTATTTGTTGGAGCAGTTCGCGGGGATTCCCACTTCTGTCTTTTACGCAAGTGA GTTTCGCTATGCACCGCCTCCACTAGCACCCCACACACTCACGATTGGGGTTACACAGTCTGGTGAGACTGCTGATACCC TCGCGGCATTGGCGATGGATGCTCAGCGTAGGCAGGCTCATGGGGAGCCTGCATTTGCGCCTCGCCAGTTAGGGGTCACG AATCGGCCAGAAAGCTCCCTGACTCGTCAGGTTCCATACATTCTCGATATCGGTGCAGGGATTGAAGTGGGGGTGGCAGC TACAAAGACCTTCTTGGGGCAGTTGTTGGCTTTCTATGGGCTTGCTTTGGCATTTGCTGCTCGTCGTAGTCACCGTTCAG TGACTGAGATTGCCAACCTAAAAGACGAACTAAGGGCTTTACCGCATCAGCTGCACTCGCTGGTGGAGCTTCATGATCAA CGCTGCGAAGTTTTAGCTAACCGCTTCGCTGATACTCAGGATGTGATCTTTTTGGGTCGTGGCATCAACTATCCCATTGC CCTTGAGGGAGCTCTCAAACTTAAGGAGATCAGCTATATCCATGCAGAGGGCTACCCAGCTGGGGAAATGAAGCATGGAC CTATTGCTTTGCTCGATGCGCGTGTGCCGGTCGTCTCGATTGCGATGCCGGGAGTGGTTTTTGAGAAGGTGCTCAGCAAT GCACAGGAGGCGAAAGCTCGTGATGCAAAGCTGATCGGTGTGGCGCCGGAGTGTCCGGATACGGCCTTGTTTGATGCTTT ACTTCCTGTCCCTGAGGTGAGCGAGTGGATCAGTCCTCTGCTCACGCTTGTCCCGATACAGCTACTGAGCTATCACATTG CTGCTCATAGGGGTCTTGATGTGGATCAGCCTCGCAACCTGGCCAAAAGCGTGACAGTGGAATAG
Upstream 100 bases:
>100_bases GGCCTGGCTTACTGATCTGAGTTCAACGTCTCAGTCTCAGTTGGCCCTGTTTTGGGCATCTACCCCATAAGCTCAGCCCG GCAGGTGCCGGGCTTTTTTT
Downstream 100 bases:
>100_bases CTCAAGCTCAATTGACGATCACGCTCTCATTACGTCCGTAGCGATCCTCAAAGCGCACGATGTCATCTTCACAGAGGTAT GGACCACTTTGTACCTCAAT
Product: glucosamine--fructose-6-phosphate aminotransferase
Products: NA
Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]
Number of amino acids: Translated: 634; Mature: 634
Protein sequence:
>634_residues MCGIVAVIGSREAAPLLLEGLRQLEYRGYDSAGLATVELLAEDGSSRLTCQRAQGKLVNLTACVEEKGAPGHCGIGHTRW ATHGKPEERNAHPHRDGSGLVAVVQNGIIENHRSLREALEAEGVRFVSETDTEVIPHLISLELRALQVQGRVVNGRMLLE AVQRVLPQLKGAYALAVVWGEVPGALVVARKQAPLLIGLGEGEFLCASDTPALAGFTRTILPMEDGEVALLTPLGIELYD AQGERQQRSPSLLSGGDQVADKRHFRHFMLKEIHEQPETAELWVARHLPPDLSSDDPVALPFDHSFYADLERIQILACGT SRHAALVGAYLLEQFAGIPTSVFYASEFRYAPPPLAPHTLTIGVTQSGETADTLAALAMDAQRRQAHGEPAFAPRQLGVT NRPESSLTRQVPYILDIGAGIEVGVAATKTFLGQLLAFYGLALAFAARRSHRSVTEIANLKDELRALPHQLHSLVELHDQ RCEVLANRFADTQDVIFLGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDARVPVVSIAMPGVVFEKVLSN AQEAKARDAKLIGVAPECPDTALFDALLPVPEVSEWISPLLTLVPIQLLSYHIAAHRGLDVDQPRNLAKSVTVE
Sequences:
>Translated_634_residues MCGIVAVIGSREAAPLLLEGLRQLEYRGYDSAGLATVELLAEDGSSRLTCQRAQGKLVNLTACVEEKGAPGHCGIGHTRW ATHGKPEERNAHPHRDGSGLVAVVQNGIIENHRSLREALEAEGVRFVSETDTEVIPHLISLELRALQVQGRVVNGRMLLE AVQRVLPQLKGAYALAVVWGEVPGALVVARKQAPLLIGLGEGEFLCASDTPALAGFTRTILPMEDGEVALLTPLGIELYD AQGERQQRSPSLLSGGDQVADKRHFRHFMLKEIHEQPETAELWVARHLPPDLSSDDPVALPFDHSFYADLERIQILACGT SRHAALVGAYLLEQFAGIPTSVFYASEFRYAPPPLAPHTLTIGVTQSGETADTLAALAMDAQRRQAHGEPAFAPRQLGVT NRPESSLTRQVPYILDIGAGIEVGVAATKTFLGQLLAFYGLALAFAARRSHRSVTEIANLKDELRALPHQLHSLVELHDQ RCEVLANRFADTQDVIFLGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDARVPVVSIAMPGVVFEKVLSN AQEAKARDAKLIGVAPECPDTALFDALLPVPEVSEWISPLLTLVPIQLLSYHIAAHRGLDVDQPRNLAKSVTVE >Mature_634_residues MCGIVAVIGSREAAPLLLEGLRQLEYRGYDSAGLATVELLAEDGSSRLTCQRAQGKLVNLTACVEEKGAPGHCGIGHTRW ATHGKPEERNAHPHRDGSGLVAVVQNGIIENHRSLREALEAEGVRFVSETDTEVIPHLISLELRALQVQGRVVNGRMLLE AVQRVLPQLKGAYALAVVWGEVPGALVVARKQAPLLIGLGEGEFLCASDTPALAGFTRTILPMEDGEVALLTPLGIELYD AQGERQQRSPSLLSGGDQVADKRHFRHFMLKEIHEQPETAELWVARHLPPDLSSDDPVALPFDHSFYADLERIQILACGT SRHAALVGAYLLEQFAGIPTSVFYASEFRYAPPPLAPHTLTIGVTQSGETADTLAALAMDAQRRQAHGEPAFAPRQLGVT NRPESSLTRQVPYILDIGAGIEVGVAATKTFLGQLLAFYGLALAFAARRSHRSVTEIANLKDELRALPHQLHSLVELHDQ RCEVLANRFADTQDVIFLGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDARVPVVSIAMPGVVFEKVLSN AQEAKARDAKLIGVAPECPDTALFDALLPVPEVSEWISPLLTLVPIQLLSYHIAAHRGLDVDQPRNLAKSVTVE
Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]
COG id: COG0449
COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 SIS domains [H]
Homologues:
Organism=Homo sapiens, GI4826742, Length=702, Percent_Identity=32.1937321937322, Blast_Score=320, Evalue=4e-87, Organism=Homo sapiens, GI205277386, Length=706, Percent_Identity=32.1529745042493, Blast_Score=310, Evalue=3e-84, Organism=Escherichia coli, GI1790167, Length=639, Percent_Identity=44.9139280125196, Blast_Score=477, Evalue=1e-135, Organism=Escherichia coli, GI87082251, Length=324, Percent_Identity=24.0740740740741, Blast_Score=84, Evalue=3e-17, Organism=Escherichia coli, GI1788651, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17532897, Length=447, Percent_Identity=35.1230425055928, Blast_Score=229, Evalue=4e-60, Organism=Caenorhabditis elegans, GI17532899, Length=447, Percent_Identity=35.1230425055928, Blast_Score=228, Evalue=5e-60, Organism=Caenorhabditis elegans, GI17539970, Length=447, Percent_Identity=35.5704697986577, Blast_Score=228, Evalue=6e-60, Organism=Saccharomyces cerevisiae, GI6322745, Length=444, Percent_Identity=32.2072072072072, Blast_Score=218, Evalue=3e-57, Organism=Saccharomyces cerevisiae, GI6323731, Length=443, Percent_Identity=26.410835214447, Blast_Score=133, Evalue=7e-32, Organism=Saccharomyces cerevisiae, GI6323730, Length=212, Percent_Identity=36.3207547169811, Blast_Score=110, Evalue=5e-25, Organism=Drosophila melanogaster, GI21357745, Length=705, Percent_Identity=33.4751773049645, Blast_Score=332, Evalue=6e-91,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000583 - InterPro: IPR017932 - InterPro: IPR005855 - InterPro: IPR001347 [H]
Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]
EC number: =2.6.1.16 [H]
Molecular weight: Translated: 68672; Mature: 68672
Theoretical pI: Translated: 5.94; Mature: 5.94
Prosite motif: PS00443 GATASE_TYPE_II
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.1 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MCGIVAVIGSREAAPLLLEGLRQLEYRGYDSAGLATVELLAEDGSSRLTCQRAQGKLVNL CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCEEEE TACVEEKGAPGHCGIGHTRWATHGKPEERNAHPHRDGSGLVAVVQNGIIENHRSLREALE EEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH AEGVRFVSETDTEVIPHLISLELRALQVQGRVVNGRMLLEAVQRVLPQLKGAYALAVVWG HCCCEEECCCCHHHHHHHHHHHHEEEEECCEEECHHHHHHHHHHHHHHHCCCEEEEEEEC EVPGALVVARKQAPLLIGLGEGEFLCASDTPALAGFTRTILPMEDGEVALLTPLGIELYD CCCCEEEEEECCCCEEEECCCCCEEECCCCCCHHCCCEEEEECCCCCEEEEECCCEEEEC AQGERQQRSPSLLSGGDQVADKRHFRHFMLKEIHEQPETAELWVARHLPPDLSSDDPVAL CCCCHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCEEE PFDHSFYADLERIQILACGTSRHAALVGAYLLEQFAGIPTSVFYASEFRYAPPPLAPHTL CCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEE TIGVTQSGETADTLAALAMDAQRRQAHGEPAFAPRQLGVTNRPESSLTRQVPYILDIGAG EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCC IEVGVAATKTFLGQLLAFYGLALAFAARRSHRSVTEIANLKDELRALPHQLHSLVELHDQ CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH RCEVLANRFADTQDVIFLGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDA HHHHHHHHCCCCCCEEEEECCCCCCEEECCCEEEEHEEEEECCCCCCCCCCCCCEEEEEC RVPVVSIAMPGVVFEKVLSNAQEAKARDAKLIGVAPECPDTALFDALLPVPEVSEWISPL CCCEEEEECCHHHHHHHHCCHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCHHHHHHHHH LTLVPIQLLSYHIAAHRGLDVDQPRNLAKSVTVE HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC >Mature Secondary Structure MCGIVAVIGSREAAPLLLEGLRQLEYRGYDSAGLATVELLAEDGSSRLTCQRAQGKLVNL CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCEEEECCCCCEEEE TACVEEKGAPGHCGIGHTRWATHGKPEERNAHPHRDGSGLVAVVQNGIIENHRSLREALE EEEHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHH AEGVRFVSETDTEVIPHLISLELRALQVQGRVVNGRMLLEAVQRVLPQLKGAYALAVVWG HCCCEEECCCCHHHHHHHHHHHHEEEEECCEEECHHHHHHHHHHHHHHHCCCEEEEEEEC EVPGALVVARKQAPLLIGLGEGEFLCASDTPALAGFTRTILPMEDGEVALLTPLGIELYD CCCCEEEEEECCCCEEEECCCCCEEECCCCCCHHCCCEEEEECCCCCEEEEECCCEEEEC AQGERQQRSPSLLSGGDQVADKRHFRHFMLKEIHEQPETAELWVARHLPPDLSSDDPVAL CCCCHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCEEE PFDHSFYADLERIQILACGTSRHAALVGAYLLEQFAGIPTSVFYASEFRYAPPPLAPHTL CCCCHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEE TIGVTQSGETADTLAALAMDAQRRQAHGEPAFAPRQLGVTNRPESSLTRQVPYILDIGAG EEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCEEEEECCC IEVGVAATKTFLGQLLAFYGLALAFAARRSHRSVTEIANLKDELRALPHQLHSLVELHDQ CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH RCEVLANRFADTQDVIFLGRGINYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALLDA HHHHHHHHCCCCCCEEEEECCCCCCEEECCCEEEEHEEEEECCCCCCCCCCCCCEEEEEC RVPVVSIAMPGVVFEKVLSNAQEAKARDAKLIGVAPECPDTALFDALLPVPEVSEWISPL CCCEEEEECCHHHHHHHHCCHHHHHHCCCEEEEECCCCCCHHHHHHHCCCCHHHHHHHHH LTLVPIQLLSYHIAAHRGLDVDQPRNLAKSVTVE HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12240834 [H]