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The map label for this gene is glmM

Identifier: 124024131

GI number: 124024131

Start: 2148183

End: 2149589

Strand: Reverse

Name: glmM

Synonym: P9303_24421

Alternate gene names: 124024131

Gene position: 2149589-2148183 (Counterclockwise)

Preceding gene: 124024134

Following gene: 124024126

Centisome position: 80.13

GC content: 57.57

Gene sequence:

>1407_bases
ATGGTCTTTACTGCTCTTGACCCTTTAGGTGTTCCCCTCGGGACGGCCCAGGCCAGTTTCGGCACAGATGGCATTCGCGG
TCGGGTCGGAACGTTGTTGACGCCTGCGTTTATTTTGCAGGTGGGCTACTGGTGTGGTCAGGTGTTGCCTGATCAAGGCC
CGGTGTTGATCGGGATGGATTCCCGTAGCAGTGGGGCCATGGTGGCCTCGGCATTGACGGCTGGTTTAACCGCTGCAGGT
CGGGAAGTGTGGACCTTGGGCCTATGTCCTACCCCCGCGGTGCCTGGATTAATTCGCAAGCTTGGCGCTGCAGGCGGTTT
GATGGTTTCAGCAAGTCATAACCCACCTGAAGACAATGGCATCAAGGTGTTTGGGGCCGATGGTGCCAAACTCAGCCCAG
CAAAGCAGGGTCTCATCGAAGCGGGGCTTCGCGGCGAGGCCATTGGTGACAAAGGTCGACCAACGATCACGAGTTGCGGC
CCTGCTTATCAGCGCGACGAGCTGCTTAGCCACTATCGCGATGCCCTGCTTGCCTCAGTGCTGCATCAACGCCTGGATGG
CGTGCCCATTGTGCTTGATCTCTGCTGGGGAGCGGCAACAGCCTGTGGTGCTGAGGTGTTTGCGGCCCTTGGGGCTGATC
TCACTGTGTTGCATGGTGAACCGGATGGAAGCCGCATCAATGTCGGTTGTGGTTCTACCCAGCTCGAGCCGTTGCGTCGA
GCTGTGATTGAGCGCGGCGCGATCATGGGCTTTGCCTTTGATGGGGATGCTGATCGGATGCTGGCTTTGGATGGACAGGG
TCGCGTCGTCGATGGTGACCATGTGCTCTACCTCTGGGGATCAGACCTTCAGGATCAGCAGGCTTTACCTCAACAAAGGC
TTGTGGCCACGGTGATGTCGAATCTCGGCTTTGAGAGGGCTTGGCAGCAAAGAGGTGGGGTTCTTGAACGCACGCCGGTG
GGCGATCAGCATGTCTATGCCGCCATGGTGGAGAGCAATGCGGCTTTAGGTGGTGAACAGTCTGGCCATATCCTTTCAGC
AGCTCATGGGCTTTGTGGTGATGGTGTACTCACTGCTTTGCAGCTTGCCACCCTCTGTCATGGCAGGGGGCTGAGTCTTG
GTGAGTGGTTGGATCAGAGTTTCCAGGCGTTCCCACAAAAGTTGGTCAATGTGCGCGTTCCTGATTTGGAACGACGTATG
GGTTGGCAGCATTGTGAGCCTCTGCAGGAGGCGGTCTTGGCGGCAGAAGCAGCCATGGGTGAAGACGGCAGAGTCTTGGT
AAGGGCGAGTGGAACGGAGCCGTTGTTAAGGGTGATGATTGAAGCGTCGGATTCTGCTGCCGTAGAGTTCTGGACAGTAC
AGTTGGCCGACCTTGCCGAGCAACACCTCAATCGGGGTTGCGTTTGA

Upstream 100 bases:

>100_bases
ACCCCCATGCTTTTGGCGTTGAGACTGTCTTCGATCATGTCCCCTCTCGATTGAGTCTCAGCCGCATGCCCTTTAATCTT
CAGTCCACTATTGAGACCTG

Downstream 100 bases:

>100_bases
GTTGGCGGAGTGCAAGCTGCAAAGCACCATCCAGGGCATCCCCCTGGCCTTTGATCCAGCTTGCAGTAGGCAGTCGCTTG
GCAATGGCTTGCTCGATCAG

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MVFTALDPLGVPLGTAQASFGTDGIRGRVGTLLTPAFILQVGYWCGQVLPDQGPVLIGMDSRSSGAMVASALTAGLTAAG
REVWTLGLCPTPAVPGLIRKLGAAGGLMVSASHNPPEDNGIKVFGADGAKLSPAKQGLIEAGLRGEAIGDKGRPTITSCG
PAYQRDELLSHYRDALLASVLHQRLDGVPIVLDLCWGAATACGAEVFAALGADLTVLHGEPDGSRINVGCGSTQLEPLRR
AVIERGAIMGFAFDGDADRMLALDGQGRVVDGDHVLYLWGSDLQDQQALPQQRLVATVMSNLGFERAWQQRGGVLERTPV
GDQHVYAAMVESNAALGGEQSGHILSAAHGLCGDGVLTALQLATLCHGRGLSLGEWLDQSFQAFPQKLVNVRVPDLERRM
GWQHCEPLQEAVLAAEAAMGEDGRVLVRASGTEPLLRVMIEASDSAAVEFWTVQLADLAEQHLNRGCV

Sequences:

>Translated_468_residues
MVFTALDPLGVPLGTAQASFGTDGIRGRVGTLLTPAFILQVGYWCGQVLPDQGPVLIGMDSRSSGAMVASALTAGLTAAG
REVWTLGLCPTPAVPGLIRKLGAAGGLMVSASHNPPEDNGIKVFGADGAKLSPAKQGLIEAGLRGEAIGDKGRPTITSCG
PAYQRDELLSHYRDALLASVLHQRLDGVPIVLDLCWGAATACGAEVFAALGADLTVLHGEPDGSRINVGCGSTQLEPLRR
AVIERGAIMGFAFDGDADRMLALDGQGRVVDGDHVLYLWGSDLQDQQALPQQRLVATVMSNLGFERAWQQRGGVLERTPV
GDQHVYAAMVESNAALGGEQSGHILSAAHGLCGDGVLTALQLATLCHGRGLSLGEWLDQSFQAFPQKLVNVRVPDLERRM
GWQHCEPLQEAVLAAEAAMGEDGRVLVRASGTEPLLRVMIEASDSAAVEFWTVQLADLAEQHLNRGCV
>Mature_468_residues
MVFTALDPLGVPLGTAQASFGTDGIRGRVGTLLTPAFILQVGYWCGQVLPDQGPVLIGMDSRSSGAMVASALTAGLTAAG
REVWTLGLCPTPAVPGLIRKLGAAGGLMVSASHNPPEDNGIKVFGADGAKLSPAKQGLIEAGLRGEAIGDKGRPTITSCG
PAYQRDELLSHYRDALLASVLHQRLDGVPIVLDLCWGAATACGAEVFAALGADLTVLHGEPDGSRINVGCGSTQLEPLRR
AVIERGAIMGFAFDGDADRMLALDGQGRVVDGDHVLYLWGSDLQDQQALPQQRLVATVMSNLGFERAWQQRGGVLERTPV
GDQHVYAAMVESNAALGGEQSGHILSAAHGLCGDGVLTALQLATLCHGRGLSLGEWLDQSFQAFPQKLVNVRVPDLERRM
GWQHCEPLQEAVLAAEAAMGEDGRVLVRASGTEPLLRVMIEASDSAAVEFWTVQLADLAEQHLNRGCV

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=462, Percent_Identity=38.0952380952381, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1788361, Length=438, Percent_Identity=27.6255707762557, Blast_Score=122, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_PROM3 (A2CCG3)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001018438.1
- ProteinModelPortal:   A2CCG3
- SMR:   A2CCG3
- STRING:   A2CCG3
- GeneID:   4778973
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_24421
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK14317
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49168; Mature: 49168

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFTALDPLGVPLGTAQASFGTDGIRGRVGTLLTPAFILQVGYWCGQVLPDQGPVLIGMD
CEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
SRSSGAMVASALTAGLTAAGREVWTLGLCPTPAVPGLIRKLGAAGGLMVSASHNPPEDNG
CCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCC
IKVFGADGAKLSPAKQGLIEAGLRGEAIGDKGRPTITSCGPAYQRDELLSHYRDALLASV
EEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LHQRLDGVPIVLDLCWGAATACGAEVFAALGADLTVLHGEPDGSRINVGCGSTQLEPLRR
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCHHHHHHH
AVIERGAIMGFAFDGDADRMLALDGQGRVVDGDHVLYLWGSDLQDQQALPQQRLVATVMS
HHHHCCCEEEEEECCCCCCEEEECCCCCEECCCEEEEEECCCCCHHHCCCHHHHHHHHHH
NLGFERAWQQRGGVLERTPVGDQHVYAAMVESNAALGGEQSGHILSAAHGLCGDGVLTAL
HCCHHHHHHHHCCEEEECCCCCCHHEEEEECCCCCCCCCCCCCEEHHHCCCCCHHHHHHH
QLATLCHGRGLSLGEWLDQSFQAFPQKLVNVRVPDLERRMGWQHCEPLQEAVLAAEAAMG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCC
EDGRVLVRASGTEPLLRVMIEASDSAAVEFWTVQLADLAEQHLNRGCV
CCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVFTALDPLGVPLGTAQASFGTDGIRGRVGTLLTPAFILQVGYWCGQVLPDQGPVLIGMD
CEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEC
SRSSGAMVASALTAGLTAAGREVWTLGLCPTPAVPGLIRKLGAAGGLMVSASHNPPEDNG
CCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCCCCCCC
IKVFGADGAKLSPAKQGLIEAGLRGEAIGDKGRPTITSCGPAYQRDELLSHYRDALLASV
EEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LHQRLDGVPIVLDLCWGAATACGAEVFAALGADLTVLHGEPDGSRINVGCGSTQLEPLRR
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCHHHHHHH
AVIERGAIMGFAFDGDADRMLALDGQGRVVDGDHVLYLWGSDLQDQQALPQQRLVATVMS
HHHHCCCEEEEEECCCCCCEEEECCCCCEECCCEEEEEECCCCCHHHCCCHHHHHHHHHH
NLGFERAWQQRGGVLERTPVGDQHVYAAMVESNAALGGEQSGHILSAAHGLCGDGVLTAL
HCCHHHHHHHHCCEEEECCCCCCHHEEEEECCCCCCCCCCCCCEEHHHCCCCCHHHHHHH
QLATLCHGRGLSLGEWLDQSFQAFPQKLVNVRVPDLERRMGWQHCEPLQEAVLAAEAAMG
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCC
EDGRVLVRASGTEPLLRVMIEASDSAAVEFWTVQLADLAEQHLNRGCV
CCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA