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The map label for this gene is yfiS [H]

Identifier: 124023837

GI number: 124023837

Start: 1906626

End: 1908041

Strand: Direct

Name: yfiS [H]

Synonym: P9303_21441

Alternate gene names: 124023837

Gene position: 1906626-1908041 (Clockwise)

Preceding gene: 124023836

Following gene: 124023838

Centisome position: 71.07

GC content: 57.84

Gene sequence:

>1416_bases
ATGGGCGAACATAACCTCGGCACCACAAGCATCTTGAGCGGTCCAACTCTAAACAGCCCCGAACCGGCCCTACCGACCGG
CTCGAATCCAGAAGGACGCCGCGGATTGGCAGCGGTGATCAAGCTGGATGGCTTTCGCCGGCTGTGGATCGGTCAGATCT
TCTCCCAACTGGCCGACAAGTTCTACATCGTTTTGATGGTGTACCTGATTGCCCAGTACTGGGTGAGCAGTACCCCTCAA
AGCAATGAGGCGCTTGCAGAGGTGGCGGCGGCGATTCGGATGGATTTCGAAACCCGCGCCCAAAAGATCACCCTGCTTGC
CACAGGCATTTATGTAGCCAACACCATTCCAGCAATGTTGCTAGGAACCGTGGCGGGTGTCTGGGCTGATCGCTGGCCGA
AACGTCGCGTGATGGTGGCCTCCAACGCGCTGCGTGCTCTGCTGGTGCTCTTGGCCCCAGTTTGTCTCTTGCCAGGTCCC
CATTGGCTGGGTCTCAGCTGGGGGTACTGGGCACTGCTGGTGATGACCTTTCTGGAGTCAGTTCTCACCCAATTCTTCGC
GCCAGCCGAGCAAGCAACCATCCCTCAACTGGTGCCAAAGGAACATCTCCTGGCTGCCAATTCCCTGTATCAAGCAACCA
GCATGGGCGCCACGATTGTGGGCTTTGCCCTTGGTGATCCAATCTTGCGTCTACTCAAACAAGCCTTCCTCTCCCTAGGA
CTGAATGGAGGGGAATTTCTGCTCCTACCGTTCTGCTACGGCATGGCAGCGATCAGCCTGAGCACGATCCAGATGCAGGA
GCAACCTCGCGACAGCTCTAGAGAAAGTGTCTGGAAGGAAATCGGCGATGGTCTGCAGGTGCTTCGTCAACAGGCTGCTG
TGCGAGGGGCAATGCTCCACCTTGTTGTGATCTATAGCCTGCTAGCCGCCATGTACGTGCTGGCCATCACCTTGGCAGGT
TCGATCAAAGGTTTGGGGCCAACTGGTTTCGGCATGATCTTGGCGATGAGTGGGATTGGGATGGCCCTGGGGGCTGTGGT
GATGGCCCAAACCGGCCACCGCTTCAACCGCCGCAACTTGTGCGCAACCGGCCTGGGCACAATCGCCTGCACCCTTGTGC
TGCTTGGGGGAGTCCTTGGTTCTCTGGGACCAACTCTTTTGCTATGCGGCTTGCTGGGCGTGGGAGCAGCCCTTGTAGCG
ATTCCAGCCCAGACCACCATTCAAGAAGACACGCCAGAAGCACAGCGCGGCAAGGTGTTTGGTCTACAAAACAACCTCAT
CAACATCACCCTGAGTCTGCCTCTTGTGCTGGCTGGCGCTCTGGTGGGCAGCTATGGGCTCGTGCCAGTGCTGTGGTTGC
TTGCTGCACTTGCCCTAGTAGCAGCTTTATTAGAGCGCCCTTGGCAGCGCTGCTAG

Upstream 100 bases:

>100_bases
CTGCGCTTGCTCGCGGTAGTGGAGTGCTGGATCCGCACCCATCTGCCACATCACATGCGAGCTCTAGGGATGTTGCGCGA
GGCCATCATCAGCTCAGGCG

Downstream 100 bases:

>100_bases
CTTTCACATTCGGCAGGAGGATTGCAGCAGGTGGCTCACATTGCCTGGCTAGGCAAAAAAACACCGTTCTGCGGCAACGT
CACCTACGGTCTCAACACGA

Product: multidrug efflux transporter MFS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MGEHNLGTTSILSGPTLNSPEPALPTGSNPEGRRGLAAVIKLDGFRRLWIGQIFSQLADKFYIVLMVYLIAQYWVSSTPQ
SNEALAEVAAAIRMDFETRAQKITLLATGIYVANTIPAMLLGTVAGVWADRWPKRRVMVASNALRALLVLLAPVCLLPGP
HWLGLSWGYWALLVMTFLESVLTQFFAPAEQATIPQLVPKEHLLAANSLYQATSMGATIVGFALGDPILRLLKQAFLSLG
LNGGEFLLLPFCYGMAAISLSTIQMQEQPRDSSRESVWKEIGDGLQVLRQQAAVRGAMLHLVVIYSLLAAMYVLAITLAG
SIKGLGPTGFGMILAMSGIGMALGAVVMAQTGHRFNRRNLCATGLGTIACTLVLLGGVLGSLGPTLLLCGLLGVGAALVA
IPAQTTIQEDTPEAQRGKVFGLQNNLINITLSLPLVLAGALVGSYGLVPVLWLLAALALVAALLERPWQRC

Sequences:

>Translated_471_residues
MGEHNLGTTSILSGPTLNSPEPALPTGSNPEGRRGLAAVIKLDGFRRLWIGQIFSQLADKFYIVLMVYLIAQYWVSSTPQ
SNEALAEVAAAIRMDFETRAQKITLLATGIYVANTIPAMLLGTVAGVWADRWPKRRVMVASNALRALLVLLAPVCLLPGP
HWLGLSWGYWALLVMTFLESVLTQFFAPAEQATIPQLVPKEHLLAANSLYQATSMGATIVGFALGDPILRLLKQAFLSLG
LNGGEFLLLPFCYGMAAISLSTIQMQEQPRDSSRESVWKEIGDGLQVLRQQAAVRGAMLHLVVIYSLLAAMYVLAITLAG
SIKGLGPTGFGMILAMSGIGMALGAVVMAQTGHRFNRRNLCATGLGTIACTLVLLGGVLGSLGPTLLLCGLLGVGAALVA
IPAQTTIQEDTPEAQRGKVFGLQNNLINITLSLPLVLAGALVGSYGLVPVLWLLAALALVAALLERPWQRC
>Mature_470_residues
GEHNLGTTSILSGPTLNSPEPALPTGSNPEGRRGLAAVIKLDGFRRLWIGQIFSQLADKFYIVLMVYLIAQYWVSSTPQS
NEALAEVAAAIRMDFETRAQKITLLATGIYVANTIPAMLLGTVAGVWADRWPKRRVMVASNALRALLVLLAPVCLLPGPH
WLGLSWGYWALLVMTFLESVLTQFFAPAEQATIPQLVPKEHLLAANSLYQATSMGATIVGFALGDPILRLLKQAFLSLGL
NGGEFLLLPFCYGMAAISLSTIQMQEQPRDSSRESVWKEIGDGLQVLRQQAAVRGAMLHLVVIYSLLAAMYVLAITLAGS
IKGLGPTGFGMILAMSGIGMALGAVVMAQTGHRFNRRNLCATGLGTIACTLVLLGGVLGSLGPTLLLCGLLGVGAALVAI
PAQTTIQEDTPEAQRGKVFGLQNNLINITLSLPLVLAGALVGSYGLVPVLWLLAALALVAALLERPWQRC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50130; Mature: 49999

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEHNLGTTSILSGPTLNSPEPALPTGSNPEGRRGLAAVIKLDGFRRLWIGQIFSQLADK
CCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
FYIVLMVYLIAQYWVSSTPQSNEALAEVAAAIRMDFETRAQKITLLATGIYVANTIPAML
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHEEHHHHHHHHHHHHHHHHH
LGTVAGVWADRWPKRRVMVASNALRALLVLLAPVCLLPGPHWLGLSWGYWALLVMTFLES
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHH
VLTQFFAPAEQATIPQLVPKEHLLAANSLYQATSMGATIVGFALGDPILRLLKQAFLSLG
HHHHHCCCCHHCCCCHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
LNGGEFLLLPFCYGMAAISLSTIQMQEQPRDSSRESVWKEIGDGLQVLRQQAAVRGAMLH
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVIYSLLAAMYVLAITLAGSIKGLGPTGFGMILAMSGIGMALGAVVMAQTGHRFNRRNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
CATGLGTIACTLVLLGGVLGSLGPTLLLCGLLGVGAALVAIPAQTTIQEDTPEAQRGKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHCCCEE
GLQNNLINITLSLPLVLAGALVGSYGLVPVLWLLAALALVAALLERPWQRC
EECCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEHNLGTTSILSGPTLNSPEPALPTGSNPEGRRGLAAVIKLDGFRRLWIGQIFSQLADK
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHH
FYIVLMVYLIAQYWVSSTPQSNEALAEVAAAIRMDFETRAQKITLLATGIYVANTIPAML
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHEEHHHHHHHHHHHHHHHHH
LGTVAGVWADRWPKRRVMVASNALRALLVLLAPVCLLPGPHWLGLSWGYWALLVMTFLES
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHH
VLTQFFAPAEQATIPQLVPKEHLLAANSLYQATSMGATIVGFALGDPILRLLKQAFLSLG
HHHHHCCCCHHCCCCHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
LNGGEFLLLPFCYGMAAISLSTIQMQEQPRDSSRESVWKEIGDGLQVLRQQAAVRGAMLH
CCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVIYSLLAAMYVLAITLAGSIKGLGPTGFGMILAMSGIGMALGAVVMAQTGHRFNRRNL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
CATGLGTIACTLVLLGGVLGSLGPTLLLCGLLGVGAALVAIPAQTTIQEDTPEAQRGKVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCHHCCCEE
GLQNNLINITLSLPLVLAGALVGSYGLVPVLWLLAALALVAALLERPWQRC
EECCCEEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]