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The map label for this gene is csd [H]

Identifier: 124023803

GI number: 124023803

Start: 1871058

End: 1872344

Strand: Direct

Name: csd [H]

Synonym: P9303_21101

Alternate gene names: 124023803

Gene position: 1871058-1872344 (Clockwise)

Preceding gene: 124023802

Following gene: 124023804

Centisome position: 69.75

GC content: 55.48

Gene sequence:

>1287_bases
ATGACCTATGTGCTGCTGCATCGGCTAGTGAAGCGAGCAGCAGATAAAACGGCAGGCGATCATGAACACAGGCCCCGACA
ACCCATGCTTAGAGACCTCTGCCCAGCACTCGCTAACAAGACCTACTTCAACTACGGCGGCCAGGGCCCCTTACCCACGC
CTTCCCTTGAAGCGATTACTGCAAGCTGGCAGAACATTCAAGAACTGGGTCCCTTCACCAACAGCGTGTGGCCCTATGTG
GCCAAAGAAGTCCAAGCCACTCGTTCACACTTAGCCAAGCTCTGCGGCGTTGCCCCCCATCGCATCGCGCTCACTGAAAA
TGTCACCAGTGGCTGTGTCTTGCCGCTCTGGGGCCTGCCTTTCTCAGAAGGCGATCGCTTGCTCATTAGCGACTGTGAAC
ATCCGGGAATCGTTGCTGCATGCATCGAACTTGCCCGCCGACAACACCTGGAAATAGACACGCTGCCTGTAAAGAACTTG
CGTCATGGTGCTAACGATCAAACGACTAGCGACAGCCTTGTGCTGGAAAGACTTGAGCAACACCTCAAACCAAGCACAAG
GCTGGTAGTGCTCTCCCACCTGCTATGGAATACAGGCCAGGTGATGCCGATCTCGGCTGTTTCAACAGCCCTCAGCCATC
ATCCACAACAGCCTTTCTTGCTCGTGGATGCGGCACAAAGCTTCGCCCAAATGCCTATACAGGAAGCCGCTGCCGCTTCA
GACATCTATGCCTTTACGGGGCACAAATGGGCCTGCGGGCCTGAAGGGCTTGGTGGAGTCGCCCTCTCAGAACGGGTGCT
CGCCGAAGCGAATCCCACCCTGATTGGCTGGCGCAGCTTGCAGAACGAAGGCCATCTTCAAAGCAACCTGGACGAACTCT
TCCATCACGACAGTCGACGCTTTGAGGTAGCAACCTCCTGCGTGCCGCTGATGGCGGGCCTGCGCTGTTCGTTGGAGCTG
CTCGAAGCCGCAGGCTCGCAGCAGGAACGACTGAGCCAGATTCGCCAAGGCAGCCGACACTTATGGAATCAACTACAACA
GCTCACAGGCGTCGAAACACTGCTCAACAGTGCCCCAGCAGCTGGTCTTGTCAGCTTTGAGTTACCCCAAGGCCCCCCAG
CTCCTGATGTGGTTAAACAATTAGGAAACGATCAGCTCTGGATTCGGCATCTAGAAGATCCAATCTGCCTACGTGCCTGC
GTGCACATCACCACTGAAGAGCAAGAACTCAACACACTTACAACCTCACTCAAGCAGCTAGCTAGCAAAGGAGAGCCAAG
CAATTAA

Upstream 100 bases:

>100_bases
TACAGACCAGAGGCAATCTCCGTTAAAAGCTCGACAAGAAAGAACATGGCAAAGTGTGATCACCTCGATTCCATCGACGA
GCTGCGACTGCGAGATCGAT

Downstream 100 bases:

>100_bases
CCATTAGCTGCGTTATCTTCTTTGCCAAAAGCAGATCAATAATCGATCTCAAAAGTTCCATTATCGACGACAAAACAAGC
CTATGAATCATAAAGAAAAT

Product: L-cysteine/cystine lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTYVLLHRLVKRAADKTAGDHEHRPRQPMLRDLCPALANKTYFNYGGQGPLPTPSLEAITASWQNIQELGPFTNSVWPYV
AKEVQATRSHLAKLCGVAPHRIALTENVTSGCVLPLWGLPFSEGDRLLISDCEHPGIVAACIELARRQHLEIDTLPVKNL
RHGANDQTTSDSLVLERLEQHLKPSTRLVVLSHLLWNTGQVMPISAVSTALSHHPQQPFLLVDAAQSFAQMPIQEAAAAS
DIYAFTGHKWACGPEGLGGVALSERVLAEANPTLIGWRSLQNEGHLQSNLDELFHHDSRRFEVATSCVPLMAGLRCSLEL
LEAAGSQQERLSQIRQGSRHLWNQLQQLTGVETLLNSAPAAGLVSFELPQGPPAPDVVKQLGNDQLWIRHLEDPICLRAC
VHITTEEQELNTLTTSLKQLASKGEPSN

Sequences:

>Translated_428_residues
MTYVLLHRLVKRAADKTAGDHEHRPRQPMLRDLCPALANKTYFNYGGQGPLPTPSLEAITASWQNIQELGPFTNSVWPYV
AKEVQATRSHLAKLCGVAPHRIALTENVTSGCVLPLWGLPFSEGDRLLISDCEHPGIVAACIELARRQHLEIDTLPVKNL
RHGANDQTTSDSLVLERLEQHLKPSTRLVVLSHLLWNTGQVMPISAVSTALSHHPQQPFLLVDAAQSFAQMPIQEAAAAS
DIYAFTGHKWACGPEGLGGVALSERVLAEANPTLIGWRSLQNEGHLQSNLDELFHHDSRRFEVATSCVPLMAGLRCSLEL
LEAAGSQQERLSQIRQGSRHLWNQLQQLTGVETLLNSAPAAGLVSFELPQGPPAPDVVKQLGNDQLWIRHLEDPICLRAC
VHITTEEQELNTLTTSLKQLASKGEPSN
>Mature_427_residues
TYVLLHRLVKRAADKTAGDHEHRPRQPMLRDLCPALANKTYFNYGGQGPLPTPSLEAITASWQNIQELGPFTNSVWPYVA
KEVQATRSHLAKLCGVAPHRIALTENVTSGCVLPLWGLPFSEGDRLLISDCEHPGIVAACIELARRQHLEIDTLPVKNLR
HGANDQTTSDSLVLERLEQHLKPSTRLVVLSHLLWNTGQVMPISAVSTALSHHPQQPFLLVDAAQSFAQMPIQEAAAASD
IYAFTGHKWACGPEGLGGVALSERVLAEANPTLIGWRSLQNEGHLQSNLDELFHHDSRRFEVATSCVPLMAGLRCSLELL
EAAGSQQERLSQIRQGSRHLWNQLQQLTGVETLLNSAPAAGLVSFELPQGPPAPDVVKQLGNDQLWIRHLEDPICLRACV
HITTEEQELNTLTTSLKQLASKGEPSN

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=315, Percent_Identity=26.031746031746, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 47020; Mature: 46889

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYVLLHRLVKRAADKTAGDHEHRPRQPMLRDLCPALANKTYFNYGGQGPLPTPSLEAIT
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHH
ASWQNIQELGPFTNSVWPYVAKEVQATRSHLAKLCGVAPHRIALTENVTSGCVLPLWGLP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCC
FSEGDRLLISDCEHPGIVAACIELARRQHLEIDTLPVKNLRHGANDQTTSDSLVLERLEQ
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHH
HLKPSTRLVVLSHLLWNTGQVMPISAVSTALSHHPQQPFLLVDAAQSFAQMPIQEAAAAS
HCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEHHHHHHHHHCCHHHHHHHH
DIYAFTGHKWACGPEGLGGVALSERVLAEANPTLIGWRSLQNEGHLQSNLDELFHHDSRR
HHHEECCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHCCCCCHHHHHHHHHHCCCCH
FEVATSCVPLMAGLRCSLELLEAAGSQQERLSQIRQGSRHLWNQLQQLTGVETLLNSAPA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGLVSFELPQGPPAPDVVKQLGNDQLWIRHLEDPICLRACVHITTEEQELNTLTTSLKQL
CCEEEEECCCCCCCHHHHHHHCCCCEEEHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
ASKGEPSN
HHCCCCCC
>Mature Secondary Structure 
TYVLLHRLVKRAADKTAGDHEHRPRQPMLRDLCPALANKTYFNYGGQGPLPTPSLEAIT
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEECCCCCCCCCCCCHHHHH
ASWQNIQELGPFTNSVWPYVAKEVQATRSHLAKLCGVAPHRIALTENVTSGCVLPLWGLP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCC
FSEGDRLLISDCEHPGIVAACIELARRQHLEIDTLPVKNLRHGANDQTTSDSLVLERLEQ
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHH
HLKPSTRLVVLSHLLWNTGQVMPISAVSTALSHHPQQPFLLVDAAQSFAQMPIQEAAAAS
HCCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEHHHHHHHHHCCHHHHHHHH
DIYAFTGHKWACGPEGLGGVALSERVLAEANPTLIGWRSLQNEGHLQSNLDELFHHDSRR
HHHEECCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEHHHHCCCCCHHHHHHHHHHCCCCH
FEVATSCVPLMAGLRCSLELLEAAGSQQERLSQIRQGSRHLWNQLQQLTGVETLLNSAPA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
AGLVSFELPQGPPAPDVVKQLGNDQLWIRHLEDPICLRACVHITTEEQELNTLTTSLKQL
CCEEEEECCCCCCCHHHHHHHCCCCEEEHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHH
ASKGEPSN
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]