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The map label for this gene is resE [H]

Identifier: 124023775

GI number: 124023775

Start: 1837273

End: 1838763

Strand: Reverse

Name: resE [H]

Synonym: P9303_20811

Alternate gene names: 124023775

Gene position: 1838763-1837273 (Counterclockwise)

Preceding gene: 124023776

Following gene: 124023773

Centisome position: 68.54

GC content: 46.68

Gene sequence:

>1491_bases
TTGAACGCAAGAGGGGCCTGGATCAATTTCAGGCATCCGCCTTATTCGATCCGCCGCGTTCTAGAGCGCACCAGCTTGAT
GGCTGTGGGGCTGGGATATGGGTTGTTGTTGTTGTTTAACCTGCAGCTTCCAGCTGAACAGCGTAGGCAGGCTCAGCGGG
AAGACCTTGACGATGCCAAGGCTATTCTTCGTCAGTCGAAGGATTTGATCCTTCGCGCCGATTCAGTGTCGGCATCTGAA
AACAGTATTGATCCACTTTTGCTGAAGAGATTGCTGAGTGATTTTTCATCTTTTCATCTTTTGATTTCGATGCACCCCAA
GGGGTTTGAGGCTGGTTTTGTGATGCCTGATGTGAGAGGAGACATCAGTCTTGGCAGGGTTCTATCTTCTTATGGCTTGC
AAAAATATCAAGGTGATGCCAAATATGGTCCTGTTCTTATTGATATTGATTCGGCTTATTATTCAATCATTAAAGATGAA
ATTGAGCTGCATGGAAATACTTGGAATATTTATCTTGTGCAGGATGTTAGTCGTCAGATTCGCCAGCAAAATATTCTAAC
CATCATTCTTATTCTAGCTGCTTTACTTGCTTCGATGGTGACCTTATTCCTCACGCGTACAGGCATTCGACGAGGTTTGG
AGCCTTTGCAGCGCTTTGGCGGAGTGATCGAATCAGTCTCGTCTGGAACTCTCGACGATCATCGCTGTGATCCGAAATAT
GAACCTGTGGAACTTAAGTCGCTTGCCGGTTCGTTTAATGCGCTTTTAGATCATTTGGCTGATTCTTGGAATCGTCAGAG
GAAGTTTGCCAATGCTCTCAGCCATGAACTGCGCACACCGATTACTTTGATTATTGGCTATACCTCCAGGGTTTTGCGCC
GATCAGGAAACCTTAGTGAAGATCAGCGGCATCAATTGACGATTATTGATGATGAGACTCGTCGTCTCGGAAGGTTAATC
ACTGATCTATTAGATATTGCGCGTGAGGAATCTGGCACTCTGGTGATTACGTCAGAGCCTTTTTCCGCATTTGAGACGTT
AGAGCAGGTGCTTTTACTAAACCAAGGTGATCATGAGACTCGCTTGAAAATCCAATCGAGTTCAAACGGTTTTGATCAGA
TCTGGGCTCTTGGTGATCACGATAGGGTCGTGCAGTGTCTTAGTAATTTGATTGAGAATGCTTTTAAGTACAGCCCAGAA
GACAAGCGAGTTGAATTGAGCTGCAATAGCACGCATGAGCATGTGAGATTGCAAGTTCGTGATCATGGCCCTGGTGTGCC
AGAGGCTGATCAGGAGCTGATTTTTGAACAGTTTCAGCGCGGCAGTAACACGGCACAACAACCTGGTAGTGGCGTTGGTC
TGGCACTTGTGAGCTCGTTGGTGAAGCGGATGGGAGGCCGCATTTGGGTTGAGAATGCTGCTGATGGTGGAGCGATCTTT
GTGATTGAGTTGCAACGTTGTCAGCCGCCTGATCCTGAATACGCCATTTAG

Upstream 100 bases:

>100_bases
ATGAATGATCTAGGCCACAGCGTTAGTCGTATAAAACGGCAAAAGTATGCAATGCTAAGCGAAGAGCTCCTGGCTGGACA
TTAACCGTCTTGGCAAATCA

Downstream 100 bases:

>100_bases
CTTCGGAACTATTCGACAGTGACGACAAGTGATTCACGAATGAACTTCAAAGGTGTTTTCATTAATTAGTGAAGTAAATA
GCAAATGTGTACCCTCTCTA

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MNARGAWINFRHPPYSIRRVLERTSLMAVGLGYGLLLLFNLQLPAEQRRQAQREDLDDAKAILRQSKDLILRADSVSASE
NSIDPLLLKRLLSDFSSFHLLISMHPKGFEAGFVMPDVRGDISLGRVLSSYGLQKYQGDAKYGPVLIDIDSAYYSIIKDE
IELHGNTWNIYLVQDVSRQIRQQNILTIILILAALLASMVTLFLTRTGIRRGLEPLQRFGGVIESVSSGTLDDHRCDPKY
EPVELKSLAGSFNALLDHLADSWNRQRKFANALSHELRTPITLIIGYTSRVLRRSGNLSEDQRHQLTIIDDETRRLGRLI
TDLLDIAREESGTLVITSEPFSAFETLEQVLLLNQGDHETRLKIQSSSNGFDQIWALGDHDRVVQCLSNLIENAFKYSPE
DKRVELSCNSTHEHVRLQVRDHGPGVPEADQELIFEQFQRGSNTAQQPGSGVGLALVSSLVKRMGGRIWVENAADGGAIF
VIELQRCQPPDPEYAI

Sequences:

>Translated_496_residues
MNARGAWINFRHPPYSIRRVLERTSLMAVGLGYGLLLLFNLQLPAEQRRQAQREDLDDAKAILRQSKDLILRADSVSASE
NSIDPLLLKRLLSDFSSFHLLISMHPKGFEAGFVMPDVRGDISLGRVLSSYGLQKYQGDAKYGPVLIDIDSAYYSIIKDE
IELHGNTWNIYLVQDVSRQIRQQNILTIILILAALLASMVTLFLTRTGIRRGLEPLQRFGGVIESVSSGTLDDHRCDPKY
EPVELKSLAGSFNALLDHLADSWNRQRKFANALSHELRTPITLIIGYTSRVLRRSGNLSEDQRHQLTIIDDETRRLGRLI
TDLLDIAREESGTLVITSEPFSAFETLEQVLLLNQGDHETRLKIQSSSNGFDQIWALGDHDRVVQCLSNLIENAFKYSPE
DKRVELSCNSTHEHVRLQVRDHGPGVPEADQELIFEQFQRGSNTAQQPGSGVGLALVSSLVKRMGGRIWVENAADGGAIF
VIELQRCQPPDPEYAI
>Mature_496_residues
MNARGAWINFRHPPYSIRRVLERTSLMAVGLGYGLLLLFNLQLPAEQRRQAQREDLDDAKAILRQSKDLILRADSVSASE
NSIDPLLLKRLLSDFSSFHLLISMHPKGFEAGFVMPDVRGDISLGRVLSSYGLQKYQGDAKYGPVLIDIDSAYYSIIKDE
IELHGNTWNIYLVQDVSRQIRQQNILTIILILAALLASMVTLFLTRTGIRRGLEPLQRFGGVIESVSSGTLDDHRCDPKY
EPVELKSLAGSFNALLDHLADSWNRQRKFANALSHELRTPITLIIGYTSRVLRRSGNLSEDQRHQLTIIDDETRRLGRLI
TDLLDIAREESGTLVITSEPFSAFETLEQVLLLNQGDHETRLKIQSSSNGFDQIWALGDHDRVVQCLSNLIENAFKYSPE
DKRVELSCNSTHEHVRLQVRDHGPGVPEADQELIFEQFQRGSNTAQQPGSGVGLALVSSLVKRMGGRIWVENAADGGAIF
VIELQRCQPPDPEYAI

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=321, Percent_Identity=28.0373831775701, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789149, Length=223, Percent_Identity=31.390134529148, Blast_Score=112, Evalue=8e-26,
Organism=Escherichia coli, GI1788279, Length=283, Percent_Identity=30.0353356890459, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=29.0909090909091, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=276, Percent_Identity=28.9855072463768, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=30.3030303030303, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=27.0916334661355, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=282, Percent_Identity=28.0141843971631, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=29.646017699115, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787374, Length=235, Percent_Identity=28.936170212766, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=246, Percent_Identity=26.0162601626016, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=26.0089686098655, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786837, Length=119, Percent_Identity=36.9747899159664, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789403, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790551, Length=289, Percent_Identity=22.4913494809689, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55703; Mature: 55703

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARGAWINFRHPPYSIRRVLERTSLMAVGLGYGLLLLFNLQLPAEQRRQAQREDLDDAK
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCHHHHH
AILRQSKDLILRADSVSASENSIDPLLLKRLLSDFSSFHLLISMHPKGFEAGFVMPDVRG
HHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCCC
DISLGRVLSSYGLQKYQGDAKYGPVLIDIDSAYYSIIKDEIELHGNTWNIYLVQDVSRQI
CHHHHHHHHHHCHHHHCCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
RQQNILTIILILAALLASMVTLFLTRTGIRRGLEPLQRFGGVIESVSSGTLDDHRCDPKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EPVELKSLAGSFNALLDHLADSWNRQRKFANALSHELRTPITLIIGYTSRVLRRSGNLSE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCC
DQRHQLTIIDDETRRLGRLITDLLDIAREESGTLVITSEPFSAFETLEQVLLLNQGDHET
CCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCE
RLKIQSSSNGFDQIWALGDHDRVVQCLSNLIENAFKYSPEDKRVELSCNSTHEHVRLQVR
EEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEE
DHGPGVPEADQELIFEQFQRGSNTAQQPGSGVGLALVSSLVKRMGGRIWVENAADGGAIF
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEE
VIELQRCQPPDPEYAI
EEEEECCCCCCCCCCC
>Mature Secondary Structure
MNARGAWINFRHPPYSIRRVLERTSLMAVGLGYGLLLLFNLQLPAEQRRQAQREDLDDAK
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCHHHHH
AILRQSKDLILRADSVSASENSIDPLLLKRLLSDFSSFHLLISMHPKGFEAGFVMPDVRG
HHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCEECCCCCC
DISLGRVLSSYGLQKYQGDAKYGPVLIDIDSAYYSIIKDEIELHGNTWNIYLVQDVSRQI
CHHHHHHHHHHCHHHHCCCCCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEEEHHHHHHH
RQQNILTIILILAALLASMVTLFLTRTGIRRGLEPLQRFGGVIESVSSGTLDDHRCDPKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EPVELKSLAGSFNALLDHLADSWNRQRKFANALSHELRTPITLIIGYTSRVLRRSGNLSE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCCCC
DQRHQLTIIDDETRRLGRLITDLLDIAREESGTLVITSEPFSAFETLEQVLLLNQGDHET
CCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCE
RLKIQSSSNGFDQIWALGDHDRVVQCLSNLIENAFKYSPEDKRVELSCNSTHEHVRLQVR
EEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEE
DHGPGVPEADQELIFEQFQRGSNTAQQPGSGVGLALVSSLVKRMGGRIWVENAADGGAIF
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCEEE
VIELQRCQPPDPEYAI
EEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]