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The map label for this gene is nlpI [C]

Identifier: 124023735

GI number: 124023735

Start: 1795154

End: 1795855

Strand: Direct

Name: nlpI [C]

Synonym: P9303_20371

Alternate gene names: 124023735

Gene position: 1795154-1795855 (Clockwise)

Preceding gene: 124023733

Following gene: 124023736

Centisome position: 66.92

GC content: 45.16

Gene sequence:

>702_bases
ATGCCACACACAAGAACTGCTCTTGCTGCTGCCTTATCGCTGCTGCCACTGGGGCATCCCCTGCTATTGGGATCTACTAC
TGCTCTGGCAACTGGTGCGGTGATGCTTTCAACCCAGACAGCGGTTGCTCAGAGTGCGGCAGTTTTCTTCAACCGTGGTT
ATGCCAAGGATGAATTAAAAGATTATCAAGGAGCAATTGCTGATTACACCAAGGCAATAGCGATTAATCCGCAGTATGCC
GATGCCTATAACAACCGTGGTATTGCCAAGAGAAAATCAGGAGATTATCAAGGAGCAATTGCTGATTACAACAAAGCAAT
AGAGATTAATCCGCAGGATGCCGAGGCATATTACAACCGTGGTTATGCCAAGGATGAATTAAAAGATTATCAAGGAGCAA
TTGCTGATTACACCAAGGCAATAGCGATTGATCCGCAGGATGGCGATGCCTATAACAACCGTGGTATTGCCAAGAGAAAA
TCAGGAGATTATCAAGGAGCAATTGCTGATTACAGCAAAATAATAGAGATTAATCCGCAGGATGCCGCTGCCTATAGCAA
TCGCGGAATCACTAAGGGGATAGGATTTAGCGATAGAAAAGGTGCTTGTAGTGACTTCAAAAAAGCAGCATCTCTGGGTT
ATCAATATCGAATTAACTGGTTAAACAGCGCAGATGGTGCCTGGTGCCGCAATATGCGATGA

Upstream 100 bases:

>100_bases
GTTGCTGGAGGCGCATTGTGAATGATCTAGTAGTTGTTTCCGAAGGTCTCTAACGGGCAAGAAGTCCCCACTTACCTTTA
AAGGCAGCAGCACCCACCAG

Downstream 100 bases:

>100_bases
GGTCATCAAACAACAGCACACCCAATAGACCCGATAAGACACCCCCATCTACCCTTTAAGCAGCAGAGCACTTCATTGAT
GACACGCCGAACCACTGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MPHTRTALAAALSLLPLGHPLLLGSTTALATGAVMLSTQTAVAQSAAVFFNRGYAKDELKDYQGAIADYTKAIAINPQYA
DAYNNRGIAKRKSGDYQGAIADYNKAIEINPQDAEAYYNRGYAKDELKDYQGAIADYTKAIAIDPQDGDAYNNRGIAKRK
SGDYQGAIADYSKIIEINPQDAAAYSNRGITKGIGFSDRKGACSDFKKAASLGYQYRINWLNSADGAWCRNMR

Sequences:

>Translated_233_residues
MPHTRTALAAALSLLPLGHPLLLGSTTALATGAVMLSTQTAVAQSAAVFFNRGYAKDELKDYQGAIADYTKAIAINPQYA
DAYNNRGIAKRKSGDYQGAIADYNKAIEINPQDAEAYYNRGYAKDELKDYQGAIADYTKAIAIDPQDGDAYNNRGIAKRK
SGDYQGAIADYSKIIEINPQDAAAYSNRGITKGIGFSDRKGACSDFKKAASLGYQYRINWLNSADGAWCRNMR
>Mature_232_residues
PHTRTALAAALSLLPLGHPLLLGSTTALATGAVMLSTQTAVAQSAAVFFNRGYAKDELKDYQGAIADYTKAIAINPQYAD
AYNNRGIAKRKSGDYQGAIADYNKAIEINPQDAEAYYNRGYAKDELKDYQGAIADYTKAIAIDPQDGDAYNNRGIAKRKS
GDYQGAIADYSKIIEINPQDAAAYSNRGITKGIGFSDRKGACSDFKKAASLGYQYRINWLNSADGAWCRNMR

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=137, Percent_Identity=35.036496350365, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI32307148, Length=137, Percent_Identity=35.036496350365, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI24308141, Length=155, Percent_Identity=28.3870967741935, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI310110582, Length=172, Percent_Identity=28.4883720930233, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI310123097, Length=172, Percent_Identity=28.4883720930233, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI310131789, Length=172, Percent_Identity=28.4883720930233, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4506921, Length=113, Percent_Identity=33.6283185840708, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115532692, Length=119, Percent_Identity=39.4957983193277, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115532690, Length=119, Percent_Identity=39.4957983193277, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17647755, Length=133, Percent_Identity=34.5864661654135, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24585827, Length=133, Percent_Identity=34.5864661654135, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24585829, Length=133, Percent_Identity=34.5864661654135, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 25264; Mature: 25133

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHTRTALAAALSLLPLGHPLLLGSTTALATGAVMLSTQTAVAQSAAVFFNRGYAKDELK
CCCHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCHHHHH
DYQGAIADYTKAIAINPQYADAYNNRGIAKRKSGDYQGAIADYNKAIEINPQDAEAYYNR
HHHHHHHHHHEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHC
GYAKDELKDYQGAIADYTKAIAIDPQDGDAYNNRGIAKRKSGDYQGAIADYSKIIEINPQ
CCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCC
DAAAYSNRGITKGIGFSDRKGACSDFKKAASLGYQYRINWLNSADGAWCRNMR
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure 
PHTRTALAAALSLLPLGHPLLLGSTTALATGAVMLSTQTAVAQSAAVFFNRGYAKDELK
CCHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCHHHHH
DYQGAIADYTKAIAINPQYADAYNNRGIAKRKSGDYQGAIADYNKAIEINPQDAEAYYNR
HHHHHHHHHHEEEEECCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHC
GYAKDELKDYQGAIADYTKAIAIDPQDGDAYNNRGIAKRKSGDYQGAIADYSKIIEINPQ
CCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCC
DAAAYSNRGITKGIGFSDRKGACSDFKKAASLGYQYRINWLNSADGAWCRNMR
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]