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The map label for this gene is codA [H]

Identifier: 124023689

GI number: 124023689

Start: 1749108

End: 1750325

Strand: Reverse

Name: codA [H]

Synonym: P9303_19891

Alternate gene names: 124023689

Gene position: 1750325-1749108 (Counterclockwise)

Preceding gene: 124023690

Following gene: 124023687

Centisome position: 65.25

GC content: 57.47

Gene sequence:

>1218_bases
GTGCCGCGGGGTTTGTTGACAAGGGAAGTGGATGTCTTATCAGCACGGGGAACCGCCGAGGGTCTATGTCCTCTTCGCAT
TTGTTGGCAGGACGGGCGCCTCTGCTCTTTTGAGCTGATTGATGCTGATGTTTTATCGCCGAAGCGGCTGCTCTTGCCGA
GGTTGGCAGAGCCCCATGCTCATCTCGACAAGGCATTCACCTGGCTTGAGTTTCCCAACCTGCAGGGCACCTATGGCGGT
GCGATGGTTGCGAATTTTAAGGAGCGTCAAAGCCGCACGTTGATTGGGGTGAGGCAGCGTGCTGAGAGATCTCTCAAGCT
TGCCTTGAGGTATGGCTTGAGAGCCATGCGCAGTCATGTCGACAGCCTTGGACCAGCTACCGATAGCAGCTGGGAGGCTT
TGCTGGATCTACAGCGTCAGTGGCAAGAGTGGATGGAGTTGCAATGGGTCGCTCTGGTGCCGATTGAGCACTGGAGCACC
CGCGAAGGCGATCAGCTAGCGGGTCGGGTCGCAGAGGTAGGAGGTCTGCTGGGTGGTGTGGTTGTGCCCCCTTTTGATCC
GGGGAAGACGCGAGATTCATTGCGGCAGATGCTGCAACTTGCCGATCGCTTGGGCTGTGGCATTGACCTTCACATTGATG
AGTCGCAAAGCCATCCTGCGGCTGGCTTAAAGCAACTGCTGCTGGTGCTTGATCGCATGTCAATCACAGTGCCGATCACT
TGTAGTCATGCCAGCAGCATGGGGTTGCTGCCGCCGAGAGCAGTGCGTCGTTTGGCTGATCGGATGGCGCATCATCGACT
CAATGTGGTGTCTCTGCCGCTGACCAATGGCTGGTTGTTGTCGAAGCAACCTCGTCGCACTCCTGTGGAGCGACCTCTGG
CACCTATCCATCAACTCCAGCTGGCAGGTGTAACTGTGGCTGTGGGAGGCGACAACGTTCAAGACCCCTGGTTCCCGGCT
GGCAACTTTGACCCTTTGGCATTGATGGCTTTTGCGTTGCCTTTGGCTCATCTGGCACCTTGGCAGCGCTTAGGGCTTGC
TCCTTTCACCACAGCTGCGGCCAGGGTGATGAACCTGTCGTGGGACGGAACATTGCAGCCAGGCAGCCCAGCTAACCTGC
TGCTTTTGGAGGCTGGCAGCTGGGCTGAGGCCCTAGCTACTCCACCCCGCCGTCAGGTGATTGTTGATGGAAACTGGCTG
CAAGACCTAGACCAATAA

Upstream 100 bases:

>100_bases
CAACCATTGCGGGCGCTGGGCGTTTCTTGACCATTCAGACTCGGACGGATCCGGGCAATGTGGAGTGAGCCAGGAGCGCA
AGGGATGCCTCGAGGCTTGG

Downstream 100 bases:

>100_bases
GCGTCTTTCCTCAATCAAGAAAGAGTAGGTATTTTATTGTTTGAATGTTGAAGTCTTTTGAGTTGGCATTCACATTATTG
TTTTTTTGATCCTTGTCTTG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPRGLLTREVDVLSARGTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHAHLDKAFTWLEFPNLQGTYGG
AMVANFKERQSRTLIGVRQRAERSLKLALRYGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQWVALVPIEHWST
REGDQLAGRVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLLVLDRMSITVPIT
CSHASSMGLLPPRAVRRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQLAGVTVAVGGDNVQDPWFPA
GNFDPLALMAFALPLAHLAPWQRLGLAPFTTAAARVMNLSWDGTLQPGSPANLLLLEAGSWAEALATPPRRQVIVDGNWL
QDLDQ

Sequences:

>Translated_405_residues
MPRGLLTREVDVLSARGTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHAHLDKAFTWLEFPNLQGTYGG
AMVANFKERQSRTLIGVRQRAERSLKLALRYGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQWVALVPIEHWST
REGDQLAGRVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLLVLDRMSITVPIT
CSHASSMGLLPPRAVRRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQLAGVTVAVGGDNVQDPWFPA
GNFDPLALMAFALPLAHLAPWQRLGLAPFTTAAARVMNLSWDGTLQPGSPANLLLLEAGSWAEALATPPRRQVIVDGNWL
QDLDQ
>Mature_404_residues
PRGLLTREVDVLSARGTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHAHLDKAFTWLEFPNLQGTYGGA
MVANFKERQSRTLIGVRQRAERSLKLALRYGLRAMRSHVDSLGPATDSSWEALLDLQRQWQEWMELQWVALVPIEHWSTR
EGDQLAGRVAEVGGLLGGVVVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLLVLDRMSITVPITC
SHASSMGLLPPRAVRRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQLAGVTVAVGGDNVQDPWFPAG
NFDPLALMAFALPLAHLAPWQRLGLAPFTTAAARVMNLSWDGTLQPGSPANLLLLEAGSWAEALATPPRRQVIVDGNWLQ
DLDQ

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=391, Percent_Identity=27.1099744245524, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786517, Length=360, Percent_Identity=25.2777777777778, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 44730; Mature: 44599

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRGLLTREVDVLSARGTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHA
CCCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCHH
HLDKAFTWLEFPNLQGTYGGAMVANFKERQSRTLIGVRQRAERSLKLALRYGLRAMRSHV
HHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLGPATDSSWEALLDLQRQWQEWMELQWVALVPIEHWSTREGDQLAGRVAEVGGLLGGV
HHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCE
VVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLLVLDRMSITVPIT
ECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEE
CSHASSMGLLPPRAVRRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQ
ECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCCCCHHHHHEE
LAGVTVAVGGDNVQDPWFPAGNFDPLALMAFALPLAHLAPWQRLGLAPFTTAAARVMNLS
ECCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHEECC
WDGTLQPGSPANLLLLEAGSWAEALATPPRRQVIVDGNWLQDLDQ
CCCCCCCCCCCCEEEEECCCHHHHHCCCCCCEEEECCCHHHHHCC
>Mature Secondary Structure 
PRGLLTREVDVLSARGTAEGLCPLRICWQDGRLCSFELIDADVLSPKRLLLPRLAEPHA
CCCCCHHHHHHHCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCHH
HLDKAFTWLEFPNLQGTYGGAMVANFKERQSRTLIGVRQRAERSLKLALRYGLRAMRSHV
HHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSLGPATDSSWEALLDLQRQWQEWMELQWVALVPIEHWSTREGDQLAGRVAEVGGLLGGV
HHCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCE
VVPPFDPGKTRDSLRQMLQLADRLGCGIDLHIDESQSHPAAGLKQLLLVLDRMSITVPIT
ECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEE
CSHASSMGLLPPRAVRRLADRMAHHRLNVVSLPLTNGWLLSKQPRRTPVERPLAPIHQLQ
ECCCCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCCCCHHHHHEE
LAGVTVAVGGDNVQDPWFPAGNFDPLALMAFALPLAHLAPWQRLGLAPFTTAAARVMNLS
ECCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHEECC
WDGTLQPGSPANLLLLEAGSWAEALATPPRRQVIVDGNWLQDLDQ
CCCCCCCCCCCCEEEEECCCHHHHHCCCCCCEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]