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The map label for this gene is glcD [H]

Identifier: 124023687

GI number: 124023687

Start: 1747273

End: 1748652

Strand: Reverse

Name: glcD [H]

Synonym: P9303_19871

Alternate gene names: 124023687

Gene position: 1748652-1747273 (Counterclockwise)

Preceding gene: 124023689

Following gene: 124023680

Centisome position: 65.18

GC content: 58.84

Gene sequence:

>1380_bases
ATGGATTGCCGCTATCAATTTGTCTTAGCGGTTTGGCCGATGACCAGCACCAGACTCCTTGCCGATTGTTGTGCCGAGCT
GACGGCCGTTGCTGATTTGGAGCTCATTGATGCGCCGGTTGAGTTGAAGCGCTTTTCAAGGGATGCCTATGACTTCTCTC
CTGTATTGCGAGAGCAGCTGGAGGGCTGTTGCGCCGATGTTGTTGTCCGCCCCCATACGGTGGCGGCGGTGGCGGTTGTG
GCTGGTGCTTGCACGAGGCATGGCATCCCTTTAACCCTGCGAGGTTCAGGAACAGGGAACTACGGCCAGTGCGTTCCTCT
CCAGGGGGGGGTGGTCATGCTGATGGGTGCACTGTCTAAGGTTCGGCATCTCGATCCCGACACGGGAGTAGTGACGGTGG
AGTCGGGCTGTTTGCTGCGCGATCTAGATCAACATCTTTCTCGCCATGGTCGGCAGCTGCGTTTGCTGCCATCTAGCTGG
CGAAGTGCTTCGGTGGGTGGATTCGTGGCTGGCGGCTCGGGTGGGATTGGTTCTGTGCGCTGGGGTTTCTTGCGGGATCC
AGGCCATCTGTTGGCTTTGGAGGTCGTGACCGCTGAGGATTCGCCCCAACAGTTGCAGTTGGATGCGGCTGGATCGGAGG
CCCTCAATCATGCTTACGGCAGCAATGGCATCATCACGGCCTTGAGCTTGGCAACCGCTCCGGCTGTGCCCTGGCAGGAA
GTGATGATCGATTGTGAGGATTGGTCAGAGGCCGTGGCCCTTGCGCTCCGCTGTACTCGTGCAGCGGTTGATCTGCATCT
TTGTAGCTTGCATGAGCGACCAATCGTCGATCAGCTGCCTCACTGGTGTGGTGCTTCTAATGGTCAGCATCGCCTGCTGC
TACTCGTGGCTCCCGATGGTGTTAGCACCCTGAAGCGTCTGGCAGCAGCGGCAGGAGCTCATTGCAAGGTATTGGGCCCA
GAGGCTGATCGGGGTGGCACAGGGTTGCGTGAGCTCACCTGGAACCACACCACGATGCACATGCGCGCTGTAGATCCCGA
CTGGACCTACTTGCAGATGCTTTTGCCACAGCCTGAGTTGGCTGCGATGCAGGTTCTCAAGCAGCAATGGGGCGATGATC
TTCTTTGGCATCTGGAGGCGGTGCGCCAGCAGGGTGTTCAACGCCTGGCTGCGTTACCCATCGTCCGCTGGCGCGGTCGG
CAGTCGTTGGAGCAGCTGATGAACGATTGTCGGCAGCTTGGGGCTGTTGTGTTCAACCCGCATGTGATCACTGTTGAGGA
TGGCGGGCTTGGGGTTGTTGATGCCGATCAGGTGGCGGCTAAGCGTCGTTATGACCCCAAGGGTCTGCTCAATCCAGGCA
AGCTGAGGGGCTGGTTGTAA

Upstream 100 bases:

>100_bases
GGGGCTAGTTTGCTGATATTTTTAAAGTTGAATTAGCTGCTAGGTCTAGAGATTTAGCCGCTTTGGAGGCTTGCTTGGCT
GCTTAACGTTTGCTCTGTCG

Downstream 100 bases:

>100_bases
CAGCCATTCGTTCAGCAATTCAAACTCTCGAAGGTTGCGATGCCGGTGATTTGGTTGATGCCGTCGGCATCAAGGCAAAG
GCGGCGCTGGTCATCAAGAT

Product: FAD/FMN-containing dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MDCRYQFVLAVWPMTSTRLLADCCAELTAVADLELIDAPVELKRFSRDAYDFSPVLREQLEGCCADVVVRPHTVAAVAVV
AGACTRHGIPLTLRGSGTGNYGQCVPLQGGVVMLMGALSKVRHLDPDTGVVTVESGCLLRDLDQHLSRHGRQLRLLPSSW
RSASVGGFVAGGSGGIGSVRWGFLRDPGHLLALEVVTAEDSPQQLQLDAAGSEALNHAYGSNGIITALSLATAPAVPWQE
VMIDCEDWSEAVALALRCTRAAVDLHLCSLHERPIVDQLPHWCGASNGQHRLLLLVAPDGVSTLKRLAAAAGAHCKVLGP
EADRGGTGLRELTWNHTTMHMRAVDPDWTYLQMLLPQPELAAMQVLKQQWGDDLLWHLEAVRQQGVQRLAALPIVRWRGR
QSLEQLMNDCRQLGAVVFNPHVITVEDGGLGVVDADQVAAKRRYDPKGLLNPGKLRGWL

Sequences:

>Translated_459_residues
MDCRYQFVLAVWPMTSTRLLADCCAELTAVADLELIDAPVELKRFSRDAYDFSPVLREQLEGCCADVVVRPHTVAAVAVV
AGACTRHGIPLTLRGSGTGNYGQCVPLQGGVVMLMGALSKVRHLDPDTGVVTVESGCLLRDLDQHLSRHGRQLRLLPSSW
RSASVGGFVAGGSGGIGSVRWGFLRDPGHLLALEVVTAEDSPQQLQLDAAGSEALNHAYGSNGIITALSLATAPAVPWQE
VMIDCEDWSEAVALALRCTRAAVDLHLCSLHERPIVDQLPHWCGASNGQHRLLLLVAPDGVSTLKRLAAAAGAHCKVLGP
EADRGGTGLRELTWNHTTMHMRAVDPDWTYLQMLLPQPELAAMQVLKQQWGDDLLWHLEAVRQQGVQRLAALPIVRWRGR
QSLEQLMNDCRQLGAVVFNPHVITVEDGGLGVVDADQVAAKRRYDPKGLLNPGKLRGWL
>Mature_459_residues
MDCRYQFVLAVWPMTSTRLLADCCAELTAVADLELIDAPVELKRFSRDAYDFSPVLREQLEGCCADVVVRPHTVAAVAVV
AGACTRHGIPLTLRGSGTGNYGQCVPLQGGVVMLMGALSKVRHLDPDTGVVTVESGCLLRDLDQHLSRHGRQLRLLPSSW
RSASVGGFVAGGSGGIGSVRWGFLRDPGHLLALEVVTAEDSPQQLQLDAAGSEALNHAYGSNGIITALSLATAPAVPWQE
VMIDCEDWSEAVALALRCTRAAVDLHLCSLHERPIVDQLPHWCGASNGQHRLLLLVAPDGVSTLKRLAAAAGAHCKVLGP
EADRGGTGLRELTWNHTTMHMRAVDPDWTYLQMLLPQPELAAMQVLKQQWGDDLLWHLEAVRQQGVQRLAALPIVRWRGR
QSLEQLMNDCRQLGAVVFNPHVITVEDGGLGVVDADQVAAKRRYDPKGLLNPGKLRGWL

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=245, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI37595754, Length=131, Percent_Identity=35.1145038167939, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI119964728, Length=203, Percent_Identity=26.1083743842365, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789351, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17534361, Length=259, Percent_Identity=26.2548262548263, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320023, Length=177, Percent_Identity=28.8135593220339, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320764, Length=229, Percent_Identity=25.764192139738, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18921117, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639277, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24639275, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 49754; Mature: 49754

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDCRYQFVLAVWPMTSTRLLADCCAELTAVADLELIDAPVELKRFSRDAYDFSPVLREQL
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHH
EGCCADVVVRPHTVAAVAVVAGACTRHGIPLTLRGSGTGNYGQCVPLQGGVVMLMGALSK
HHHHHHHEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHH
VRHLDPDTGVVTVESGCLLRDLDQHLSRHGRQLRLLPSSWRSASVGGFVAGGSGGIGSVR
HHCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCCCCEE
WGFLRDPGHLLALEVVTAEDSPQQLQLDAAGSEALNHAYGSNGIITALSLATAPAVPWQE
ECEECCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEHHHCCCCCHHH
VMIDCEDWSEAVALALRCTRAAVDLHLCSLHERPIVDQLPHWCGASNGQHRLLLLVAPDG
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCCEEEEEECCCC
VSTLKRLAAAAGAHCKVLGPEADRGGTGLRELTWNHTTMHMRAVDPDWTYLQMLLPQPEL
HHHHHHHHHHCCCCEEEECCCCCCCCCCCHHEECCCEEEEEEECCCCCHHHHHHCCCCHH
AAMQVLKQQWGDDLLWHLEAVRQQGVQRLAALPIVRWRGRQSLEQLMNDCRQLGAVVFNP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCEEECC
HVITVEDGGLGVVDADQVAAKRRYDPKGLLNPGKLRGWL
EEEEECCCCCCEECHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDCRYQFVLAVWPMTSTRLLADCCAELTAVADLELIDAPVELKRFSRDAYDFSPVLREQL
CCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHH
EGCCADVVVRPHTVAAVAVVAGACTRHGIPLTLRGSGTGNYGQCVPLQGGVVMLMGALSK
HHHHHHHEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEECCCCHHHHHHHHHH
VRHLDPDTGVVTVESGCLLRDLDQHLSRHGRQLRLLPSSWRSASVGGFVAGGSGGIGSVR
HHCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECCCCCCCCEE
WGFLRDPGHLLALEVVTAEDSPQQLQLDAAGSEALNHAYGSNGIITALSLATAPAVPWQE
ECEECCCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHCCCCCCEEEEEHHHCCCCCHHH
VMIDCEDWSEAVALALRCTRAAVDLHLCSLHERPIVDQLPHWCGASNGQHRLLLLVAPDG
HEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHCCCCCCCEEEEEECCCC
VSTLKRLAAAAGAHCKVLGPEADRGGTGLRELTWNHTTMHMRAVDPDWTYLQMLLPQPEL
HHHHHHHHHHCCCCEEEECCCCCCCCCCCHHEECCCEEEEEEECCCCCHHHHHHCCCCHH
AAMQVLKQQWGDDLLWHLEAVRQQGVQRLAALPIVRWRGRQSLEQLMNDCRQLGAVVFNP
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCEEECC
HVITVEDGGLGVVDADQVAAKRRYDPKGLLNPGKLRGWL
EEEEECCCCCCEECHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]