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The map label for this gene is lepB1 [H]

Identifier: 124023579

GI number: 124023579

Start: 1640260

End: 1640880

Strand: Reverse

Name: lepB1 [H]

Synonym: P9303_18791

Alternate gene names: 124023579

Gene position: 1640880-1640260 (Counterclockwise)

Preceding gene: 124023587

Following gene: 124023578

Centisome position: 61.17

GC content: 56.04

Gene sequence:

>621_bases
ATGACCCCGACACCTTCTCCTCCTCGAAAAGAAGCAAGCGGTAGCTGGCGCAGCCTGCTGCTCTGGTTGGTTCTGGCCTT
GTTGATGCGCTGGCAGGTGGTGGAGCCTCGCTGGATTCCCTCCGGTTCAATGCTGCCAACCCTTGAGTTGAAGGACCGCA
TTCTTGTTGAGAAGGTTCGCCCTCGACTTGCACGTCAACAAGAGCAGCCTTTGCCGCTGGGCAGCGTGGTGGTGTTTCAC
ACGCCACCTGCACTATTGGATGCTGGCTACGACCCCAAAGCGGCCTTGATCAAACGCGTGGTGGGGCGTCCGGGCGATCA
ACTGGAAGTTCATCATGGTCAGCTCTTGCGCAACGAGATCGCCATCAAGGATGACTGCCGTGATGCACCAATGAACTACG
AGATGGCGAAGGTGACCGTTCCTGAGCATGAACTCTGGGTGATGGGGGACAACCGCAATTCCAGTCTTGACTCTCATCTC
TGGGGGCCATTACCAGAAGAAGCTGTGATCGGAACAGCTATTTGGAGGTACTGGCCACTCAATCGGTTCGGTCCAATACG
GTTCCCCTCCCAAGGAAAGAGTGGATCTAACGACCTAGCTGCGATAGGGTCAACATCGTGA

Upstream 100 bases:

>100_bases
CAAACCAGCAGATTGTTGTGAGCAAGAGACAGAGCTTGAGCCTTAGCCAATGCGATTCTCGGTCAATACCGACCGGCGAG
GGCCGGCTTAATCAGTTTCG

Downstream 100 bases:

>100_bases
CGAAAAGCACACCGGATGTTCAACCCGGAGTTCCTGACCACCGATAACAACGATTGCCAGGACGGTAATGGGCTCATTCA
GTACCTTCAGGATCAATCCC

Product: leader peptidase I

Products: NA

Alternate protein names: SPase I-1; Leader peptidase I-1 [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTPTPSPPRKEASGSWRSLLLWLVLALLMRWQVVEPRWIPSGSMLPTLELKDRILVEKVRPRLARQQEQPLPLGSVVVFH
TPPALLDAGYDPKAALIKRVVGRPGDQLEVHHGQLLRNEIAIKDDCRDAPMNYEMAKVTVPEHELWVMGDNRNSSLDSHL
WGPLPEEAVIGTAIWRYWPLNRFGPIRFPSQGKSGSNDLAAIGSTS

Sequences:

>Translated_206_residues
MTPTPSPPRKEASGSWRSLLLWLVLALLMRWQVVEPRWIPSGSMLPTLELKDRILVEKVRPRLARQQEQPLPLGSVVVFH
TPPALLDAGYDPKAALIKRVVGRPGDQLEVHHGQLLRNEIAIKDDCRDAPMNYEMAKVTVPEHELWVMGDNRNSSLDSHL
WGPLPEEAVIGTAIWRYWPLNRFGPIRFPSQGKSGSNDLAAIGSTS
>Mature_205_residues
TPTPSPPRKEASGSWRSLLLWLVLALLMRWQVVEPRWIPSGSMLPTLELKDRILVEKVRPRLARQQEQPLPLGSVVVFHT
PPALLDAGYDPKAALIKRVVGRPGDQLEVHHGQLLRNEIAIKDDCRDAPMNYEMAKVTVPEHELWVMGDNRNSSLDSHLW
GPLPEEAVIGTAIWRYWPLNRFGPIRFPSQGKSGSNDLAAIGSTS

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23116; Mature: 22985

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPTPSPPRKEASGSWRSLLLWLVLALLMRWQVVEPRWIPSGSMLPTLELKDRILVEKVR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHH
PRLARQQEQPLPLGSVVVFHTPPALLDAGYDPKAALIKRVVGRPGDQLEVHHGQLLRNEI
HHHHHHCCCCCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHC
AIKDDCRDAPMNYEMAKVTVPEHELWVMGDNRNSSLDSHLWGPLPEEAVIGTAIWRYWPL
CCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHCCC
NRFGPIRFPSQGKSGSNDLAAIGSTS
CCCCCCCCCCCCCCCCCCEEECCCCC
>Mature Secondary Structure 
TPTPSPPRKEASGSWRSLLLWLVLALLMRWQVVEPRWIPSGSMLPTLELKDRILVEKVR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHH
PRLARQQEQPLPLGSVVVFHTPPALLDAGYDPKAALIKRVVGRPGDQLEVHHGQLLRNEI
HHHHHHCCCCCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHC
AIKDDCRDAPMNYEMAKVTVPEHELWVMGDNRNSSLDSHLWGPLPEEAVIGTAIWRYWPL
CCCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHCCC
NRFGPIRFPSQGKSGSNDLAAIGSTS
CCCCCCCCCCCCCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]