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The map label for this gene is pgsA [H]

Identifier: 124023448

GI number: 124023448

Start: 1528826

End: 1529395

Strand: Reverse

Name: pgsA [H]

Synonym: P9303_17481

Alternate gene names: 124023448

Gene position: 1529395-1528826 (Counterclockwise)

Preceding gene: 124023451

Following gene: 124023446

Centisome position: 57.01

GC content: 57.02

Gene sequence:

>570_bases
GTGAGTGCACCATCCCGCCTCGGTTCACCATCAACACTGAGAAGATCGGCAAATGCTCTAACCGTGGGGCGTTCTGCCGC
AGGCCTCCCCCTGGTGTTGTTGCTTCAATTGGGTCAGCCTGCTCTGGCATGGGTGTTGTTGCTGCTTGCAGGGCTTAGCG
ACGCCGCTGATGGCTGGCTGGCCCGAAGAGCAGGTGGTGGTAGTAGCTGGGGCGCTCGCCTGGACCCGCTTGCTGACAAG
CTTCTTCTAGCAGCACCGATGATCTGGCTGGCCAGCAACGAGGTCTTGCCTGTTTGGTCGATCTGGTTACTGCTGGCCAG
GGAACTACTGATTTCCGGTTGGCGTGCTCAAGTCTCATCTGGTGCGCCTGCTTCTTGGGGAGGTAAAGCAAAGACGATCC
TTCAATTCCTAAGCATGCTGCTGTTGTTGTGGCCGCCTAGTTGGGGAAGCCACAACTTTTGCCTAAATATGCAGCACCTG
GGCTGGTGGTTGTTCTGGCCATCTCTGTTCCTGGCGCTTAGCTCTGCGGTGGCATACATCAAACCCCGATCAAGGATTGA
TCGGCACTGA

Upstream 100 bases:

>100_bases
GATGTGGCTGGCACGACACTGAGCACAGGCGTTGACATGACATCCTTCACCGTCTGCTGGAGCACCATGAATCACATGCA
AGTTCATTCATTCTGAGCCT

Downstream 100 bases:

>100_bases
AATCTGGTTCAGCCGTTGGCTTCAAGGAGTAGTCGTTGCAGTAGCTATCTTCGAGGCCAGTCTCAAGGTCAAAGCGTGGT
TGCCAGGCCAATTCCCGCTC

Product: CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MSAPSRLGSPSTLRRSANALTVGRSAAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWLARRAGGGSSWGARLDPLADK
LLLAAPMIWLASNEVLPVWSIWLLLARELLISGWRAQVSSGAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHL
GWWLFWPSLFLALSSAVAYIKPRSRIDRH

Sequences:

>Translated_189_residues
MSAPSRLGSPSTLRRSANALTVGRSAAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWLARRAGGGSSWGARLDPLADK
LLLAAPMIWLASNEVLPVWSIWLLLARELLISGWRAQVSSGAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHL
GWWLFWPSLFLALSSAVAYIKPRSRIDRH
>Mature_188_residues
SAPSRLGSPSTLRRSANALTVGRSAAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWLARRAGGGSSWGARLDPLADKL
LLAAPMIWLASNEVLPVWSIWLLLARELLISGWRAQVSSGAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHLG
WWLFWPSLFLALSSAVAYIKPRSRIDRH

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=118, Percent_Identity=35.5932203389831, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20521; Mature: 20390

Theoretical pI: Translated: 11.88; Mature: 11.88

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPSRLGSPSTLRRSANALTVGRSAAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWL
CCCCCCCCCCHHHHHCCCHHEECCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
ARRAGGGSSWGARLDPLADKLLLAAPMIWLASNEVLPVWSIWLLLARELLISGWRAQVSS
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHLGWWLFWPSLFLALSSAVAYI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
KPRSRIDRH
CCHHHCCCC
>Mature Secondary Structure 
SAPSRLGSPSTLRRSANALTVGRSAAGLPLVLLLQLGQPALAWVLLLLAGLSDAADGWL
CCCCCCCCCHHHHHCCCHHEECCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHH
ARRAGGGSSWGARLDPLADKLLLAAPMIWLASNEVLPVWSIWLLLARELLISGWRAQVSS
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
GAPASWGGKAKTILQFLSMLLLLWPPSWGSHNFCLNMQHLGWWLFWPSLFLALSSAVAYI
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
KPRSRIDRH
CCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA