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The map label for this gene is rpe [H]

Identifier: 124023384

GI number: 124023384

Start: 1470929

End: 1471723

Strand: Reverse

Name: rpe [H]

Synonym: P9303_16821

Alternate gene names: 124023384

Gene position: 1471723-1470929 (Counterclockwise)

Preceding gene: 124023391

Following gene: 124023376

Centisome position: 54.86

GC content: 52.96

Gene sequence:

>795_bases
ATGCCGCAGGGGTTCTCGGCTCTAAAGCGCTGCTCACTGTATCAGTGCAGGCAACAACGAGAATGCCCATACAGCCGATT
CCTAGAATCGCCCACTCCACAACTCACATCGATGAGCACGAAGTCCCTGGTAATTGCACCTTCGATCCTCTCTGCCGATT
TCTCCCGCCTAGGAGAAGACGTGCAGGCTGTAGATCAAGCCGGCGCAGACTGGATTCATGTGGATGTCATGGACGGCCGA
TTTGTGCCAAATATCACGATTGGTCCTTTGATCGTTGAAGCACTAAGGCCTGTGACCAGTAAGCCCTTAGATGTCCACCT
GATGATCGTGGAACCAGAAAGGTATGTAGGAGATTTCGCAAAAGCTGGTGCAGATCACATCTATGTGCAGGTTGAAGCCT
GCCCACACCTTCACCGCAACCTTGCGCAAATCAAGGATCTCGGCAAGAAAGCAGGAGCAGTACTCAACCCAAGCACACCT
CTGGACACCCTTGAGTACTGCCTGGAGCTATGCGATCTAGTACTGATCATGAGCGTCAACCCAGGCTTCGGTGGGCAAAG
CTTCATCGACAATCAAGTGCAAAAGATCCGCGACCTGCGTCGCATTTGCGACGAACAGGGTCTCGATCCCTGGATCGAAG
TCGATGGAGGGATCAAGGCCGACAATGCCTGGAAAGTAATCGAAGCTGGCGCCAATGCGATTGTGAGCGGGTCTGGCGTG
TTCAATCAACCCGACTACGCAGAAGCTATCCGAGGCATCCGTAATAGCAAACGTCCTGAAGGTGTTCTGGTCTGA

Upstream 100 bases:

>100_bases
GGTATGCGGCGGTGGGGATGGGTGTGACGACCAAAGAAACGAGCAGGGCTGGACTGAATTCACGGGTCAGCGTTATACGC
TGATCATGTGAAAGGACCCG

Downstream 100 bases:

>100_bases
AGCAAAAGATGCAGTAATAACTGCATCTTTTGCCTATTAGTCTTGTGGGGATTTGTTGTTAAAAAGAACAGATCAACATC
AGAAGATTAGGCTTCAAAGA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MPQGFSALKRCSLYQCRQQRECPYSRFLESPTPQLTSMSTKSLVIAPSILSADFSRLGEDVQAVDQAGADWIHVDVMDGR
FVPNITIGPLIVEALRPVTSKPLDVHLMIVEPERYVGDFAKAGADHIYVQVEACPHLHRNLAQIKDLGKKAGAVLNPSTP
LDTLEYCLELCDLVLIMSVNPGFGGQSFIDNQVQKIRDLRRICDEQGLDPWIEVDGGIKADNAWKVIEAGANAIVSGSGV
FNQPDYAEAIRGIRNSKRPEGVLV

Sequences:

>Translated_264_residues
MPQGFSALKRCSLYQCRQQRECPYSRFLESPTPQLTSMSTKSLVIAPSILSADFSRLGEDVQAVDQAGADWIHVDVMDGR
FVPNITIGPLIVEALRPVTSKPLDVHLMIVEPERYVGDFAKAGADHIYVQVEACPHLHRNLAQIKDLGKKAGAVLNPSTP
LDTLEYCLELCDLVLIMSVNPGFGGQSFIDNQVQKIRDLRRICDEQGLDPWIEVDGGIKADNAWKVIEAGANAIVSGSGV
FNQPDYAEAIRGIRNSKRPEGVLV
>Mature_263_residues
PQGFSALKRCSLYQCRQQRECPYSRFLESPTPQLTSMSTKSLVIAPSILSADFSRLGEDVQAVDQAGADWIHVDVMDGRF
VPNITIGPLIVEALRPVTSKPLDVHLMIVEPERYVGDFAKAGADHIYVQVEACPHLHRNLAQIKDLGKKAGAVLNPSTPL
DTLEYCLELCDLVLIMSVNPGFGGQSFIDNQVQKIRDLRRICDEQGLDPWIEVDGGIKADNAWKVIEAGANAIVSGSGVF
NQPDYAEAIRGIRNSKRPEGVLV

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=213, Percent_Identity=39.906103286385, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI219879828, Length=213, Percent_Identity=38.0281690140845, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI24307923, Length=169, Percent_Identity=33.1360946745562, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789788, Length=216, Percent_Identity=51.3888888888889, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1790523, Length=203, Percent_Identity=36.4532019704434, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790754, Length=204, Percent_Identity=31.8627450980392, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17552948, Length=217, Percent_Identity=39.63133640553, Blast_Score=153, Evalue=8e-38,
Organism=Saccharomyces cerevisiae, GI6322341, Length=230, Percent_Identity=39.1304347826087, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24586301, Length=212, Percent_Identity=39.1509433962264, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 28984; Mature: 28852

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQGFSALKRCSLYQCRQQRECPYSRFLESPTPQLTSMSTKSLVIAPSILSADFSRLGED
CCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHCCCCCCEEECHHHHHHHHHHHHHH
VQAVDQAGADWIHVDVMDGRFVPNITIGPLIVEALRPVTSKPLDVHLMIVEPERYVGDFA
HHHHHHCCCCEEEEEEECCEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHH
KAGADHIYVQVEACPHLHRNLAQIKDLGKKAGAVLNPSTPLDTLEYCLELCDLVLIMSVN
HCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
PGFGGQSFIDNQVQKIRDLRRICDEQGLDPWIEVDGGIKADNAWKVIEAGANAIVSGSGV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCEEEECCCC
FNQPDYAEAIRGIRNSKRPEGVLV
CCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PQGFSALKRCSLYQCRQQRECPYSRFLESPTPQLTSMSTKSLVIAPSILSADFSRLGED
CCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHCCCCCCEEECHHHHHHHHHHHHHH
VQAVDQAGADWIHVDVMDGRFVPNITIGPLIVEALRPVTSKPLDVHLMIVEPERYVGDFA
HHHHHHCCCCEEEEEEECCEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHH
KAGADHIYVQVEACPHLHRNLAQIKDLGKKAGAVLNPSTPLDTLEYCLELCDLVLIMSVN
HCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEECC
PGFGGQSFIDNQVQKIRDLRRICDEQGLDPWIEVDGGIKADNAWKVIEAGANAIVSGSGV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHCCCEEEECCCC
FNQPDYAEAIRGIRNSKRPEGVLV
CCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]