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The map label for this gene is recG [H]

Identifier: 124023369

GI number: 124023369

Start: 1455177

End: 1457717

Strand: Direct

Name: recG [H]

Synonym: P9303_16671

Alternate gene names: 124023369

Gene position: 1455177-1457717 (Clockwise)

Preceding gene: 124023368

Following gene: 124023370

Centisome position: 54.24

GC content: 54.19

Gene sequence:

>2541_bases
GTGGTGGCAGAGCCCTTCCGCCAATCCTCCAACCAGTCCACCCAAGGCCTGAGTACGGATCAGTTGCAGCATCTACTCAG
CTGGATGCGCATTCTGCAGCAAGCGTTAACCCTGGAGGCTGAGAACGGTTTTAAGAATCTTGAGGGGCGTCAGGAGAATT
TTCATGCATTCTTGGTGCGTCAGTTAGCAGAACCACCCTCTGGATTGCTGCCTACTAAAAGTCAGGCTCGACTCAGCCAG
CTAGCTGAAGCCTTTGCGAGTTATCCAGACAGCTCTGAATCGGCGCGACGTCGATTGGTGACGGACTCAAGACAGCTTCT
GCATGGCATTCGCCAGGGATTAGAACCACCAGCGCCAATAGGCCCTCCCAGACTCAAGCAAGGGGAAGCTGAAAGGCAGC
GGCAGATGCCTTTACCTAGTGGGAACCGCTCTCTGAAGTTGGAAAGCCCACTGTCAGAGGTGAAAGGAATCGGCCCAAAA
CTTGCTGAACGCTTGGCCGGGCTTGGATTACTGCTCGTAAAAGATTTGCTGCAGTACTACCCCAGGGACTATGTGGATTA
TTCCTCGTTGCGGCGTATCCAGGCTCTAGAGGCAGGGGAGGCGGCCACGATTGTGGCCACAGTGAGGCGTTGTCATGGCT
TCACCAGTCCACGCAACCCAAATTTGTCCATTCTTGAGCTGCAGCTTCAAGACCCAACTGGTCGGCTCAAAGTGAGGAGA
TTTTTCGCAGGTCGGCGTTTCAGCAGCCCTGCTTACCTCAAAAGCCAGTCACGCCTTTACCCGCCTGGAGTCACTGTGGC
CGTAAGTGGATTGGTCAAAGGAGGTCCTTACGGCATGAGTTTTCAAGACCCTTTGATTGAGGTCATGGAGAGTCCGCATT
CGCCGTTGCGATCGCAAAGCATTGGCCGGTTGTTGCCTGTGTATGCCCTCACTGAAGGCCTTACGGCTGACCGTTTTCGT
GATCTGGTACGGCAGGTTTTACCTTTGGCAGCAAGTTGGCCTGAATCCCTGCCTGAACCACGTCGTCAGGCATTGCGTTT
ACCCAGCAGAAGCGATGCCTTGATCGCAATTCATCATCCAGACGATCAGCACACATTGCAGTCTGCTCGACGTCGATTGG
TCTTTGACGAGTTTCTTCTATTGCAGTTGGGGTTGCTCAAACGGCGAGCAGAGCTGCGCAGTTGTTCTGCTCCTGTATTG
CAGACGGCAGGGCAGCGAGATGGCCTTGTCGCTCGCTTCCTGGAGCTTTTGCCATTCCCTCTCACAGGAGCTCAGCAGCG
TGTGTTGAGGGAGATCGAAGCTGACCTGGTGCTCTCGGAACCAATGGCACGCCTCATTCAGGGAGATGTTGGTAGTGGCA
AGACGGTTGTCGCCATAGCAGCCCTGCTCACAGCGGTAGAGGCCGGCTGGCAAGGCGCTTTCATGGCGCCCACTGAGGTC
CTTGCCGAGCAGCACTACCGCACATTGTGTTGTTGGTTGCCTCAGTTACATGTCAGCGTCGAGTTGCTTACGGGGGCAAC
CACTCGTATACGTCGCCGTCAGATCCTTGATGATCTCGTCAATGGATCCTTGAAAATACTGGTAGGCACCCATGCCTTAA
TCGAAGATCCTGTTGCCTTTTCAAGACTGGGGCTGGTGGTGGTTGACGAACAGCATCGTTTTGGAGTGAAGCAGCGCAAC
AGATTGTTGAACAAGGGGCTCCAGCCTCATCTTTTGACCATGACAGCAACGCCCATTCCTCGCACACTGGCACTTTCGTT
GCATGGGGATTTGGATGTGAGTCAGATCGATGAATTACCTCCTGGTCGTACCCCCATTCAAACTCAGATGATTAGGGGCT
GCGATCGGGATCAGGCCTATCAACTCATCCGTGATCAAGTGTCTCGTGGCCAGCGCGCTTATGTGGTGTTACCGCTGATC
GAGGACTCCGAGAAACTTGATCTGCGTTCAGCAGTTAAGGTTCATAGCCATTTATCAGAACAGGTATTTGCGGAGTTCAC
GGTTGGATTACTGCATGGACGTTTGAGTAGCTCAGAGAAGCAGGGCGTGATTCAATCCTTCGCAGCGGGTGAATGCCAGG
TGCTGGTCTCTACCACTGTGGTGGAGGTAGGCGTGGATGTACCTCAAGCAAGTGTGATGGTGATCGACCACGCGGATCGC
TTTGGCCTAGCCCAATTGCATCAACTGCGAGGTCGTGTGGGACGTGGCGCAGCGGCGTCCCATTGCGTACTGATCAATGA
CAGCACAAACCCTTTAGCGAGGCAGCGACTTGAAGTCCTTGTGCGCTCCAGTGATGGCTTTGAGATTGCTGAGATTGACT
TACGCTTGCGAGGGCCAGGGCAGGTACTTGGCACAAAACAGTCTGGATTGCCTGATTTGGCCCTGGCCAGCCTTGCAGAT
GATGGGTCCGTACTTGAAGAGGCTCGTGATGAGGCTCAAAGACTGCTCAGCGATGATCCGAACCTGACTGACCACTCTCG
GCTCAAGGAATTGCTGGAGGCACAGTGGAAGCACCTGAGTGGCACAGCCCATCTGAATTGA

Upstream 100 bases:

>100_bases
GTCGGGCTCAACTCAAGCGACATCGCCTTACCTTGCTCAAAATGGTTCGACAACAGCGGCACTGGCAACGTCGCGCCATG
GCTCAGGAGGTAAAGCAACA

Downstream 100 bases:

>100_bases
GTCCATTGATTTTTTCCACACACTTGAGACTCGTTTGAGTCTTAATACTCAGAAATTACGAGCCGATGTGCCTTCTGCTA
CGTCGGTTGCCGGGCTGGCT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 846; Mature: 846

Protein sequence:

>846_residues
MVAEPFRQSSNQSTQGLSTDQLQHLLSWMRILQQALTLEAENGFKNLEGRQENFHAFLVRQLAEPPSGLLPTKSQARLSQ
LAEAFASYPDSSESARRRLVTDSRQLLHGIRQGLEPPAPIGPPRLKQGEAERQRQMPLPSGNRSLKLESPLSEVKGIGPK
LAERLAGLGLLLVKDLLQYYPRDYVDYSSLRRIQALEAGEAATIVATVRRCHGFTSPRNPNLSILELQLQDPTGRLKVRR
FFAGRRFSSPAYLKSQSRLYPPGVTVAVSGLVKGGPYGMSFQDPLIEVMESPHSPLRSQSIGRLLPVYALTEGLTADRFR
DLVRQVLPLAASWPESLPEPRRQALRLPSRSDALIAIHHPDDQHTLQSARRRLVFDEFLLLQLGLLKRRAELRSCSAPVL
QTAGQRDGLVARFLELLPFPLTGAQQRVLREIEADLVLSEPMARLIQGDVGSGKTVVAIAALLTAVEAGWQGAFMAPTEV
LAEQHYRTLCCWLPQLHVSVELLTGATTRIRRRQILDDLVNGSLKILVGTHALIEDPVAFSRLGLVVVDEQHRFGVKQRN
RLLNKGLQPHLLTMTATPIPRTLALSLHGDLDVSQIDELPPGRTPIQTQMIRGCDRDQAYQLIRDQVSRGQRAYVVLPLI
EDSEKLDLRSAVKVHSHLSEQVFAEFTVGLLHGRLSSSEKQGVIQSFAAGECQVLVSTTVVEVGVDVPQASVMVIDHADR
FGLAQLHQLRGRVGRGAAASHCVLINDSTNPLARQRLEVLVRSSDGFEIAEIDLRLRGPGQVLGTKQSGLPDLALASLAD
DGSVLEEARDEAQRLLSDDPNLTDHSRLKELLEAQWKHLSGTAHLN

Sequences:

>Translated_846_residues
MVAEPFRQSSNQSTQGLSTDQLQHLLSWMRILQQALTLEAENGFKNLEGRQENFHAFLVRQLAEPPSGLLPTKSQARLSQ
LAEAFASYPDSSESARRRLVTDSRQLLHGIRQGLEPPAPIGPPRLKQGEAERQRQMPLPSGNRSLKLESPLSEVKGIGPK
LAERLAGLGLLLVKDLLQYYPRDYVDYSSLRRIQALEAGEAATIVATVRRCHGFTSPRNPNLSILELQLQDPTGRLKVRR
FFAGRRFSSPAYLKSQSRLYPPGVTVAVSGLVKGGPYGMSFQDPLIEVMESPHSPLRSQSIGRLLPVYALTEGLTADRFR
DLVRQVLPLAASWPESLPEPRRQALRLPSRSDALIAIHHPDDQHTLQSARRRLVFDEFLLLQLGLLKRRAELRSCSAPVL
QTAGQRDGLVARFLELLPFPLTGAQQRVLREIEADLVLSEPMARLIQGDVGSGKTVVAIAALLTAVEAGWQGAFMAPTEV
LAEQHYRTLCCWLPQLHVSVELLTGATTRIRRRQILDDLVNGSLKILVGTHALIEDPVAFSRLGLVVVDEQHRFGVKQRN
RLLNKGLQPHLLTMTATPIPRTLALSLHGDLDVSQIDELPPGRTPIQTQMIRGCDRDQAYQLIRDQVSRGQRAYVVLPLI
EDSEKLDLRSAVKVHSHLSEQVFAEFTVGLLHGRLSSSEKQGVIQSFAAGECQVLVSTTVVEVGVDVPQASVMVIDHADR
FGLAQLHQLRGRVGRGAAASHCVLINDSTNPLARQRLEVLVRSSDGFEIAEIDLRLRGPGQVLGTKQSGLPDLALASLAD
DGSVLEEARDEAQRLLSDDPNLTDHSRLKELLEAQWKHLSGTAHLN
>Mature_846_residues
MVAEPFRQSSNQSTQGLSTDQLQHLLSWMRILQQALTLEAENGFKNLEGRQENFHAFLVRQLAEPPSGLLPTKSQARLSQ
LAEAFASYPDSSESARRRLVTDSRQLLHGIRQGLEPPAPIGPPRLKQGEAERQRQMPLPSGNRSLKLESPLSEVKGIGPK
LAERLAGLGLLLVKDLLQYYPRDYVDYSSLRRIQALEAGEAATIVATVRRCHGFTSPRNPNLSILELQLQDPTGRLKVRR
FFAGRRFSSPAYLKSQSRLYPPGVTVAVSGLVKGGPYGMSFQDPLIEVMESPHSPLRSQSIGRLLPVYALTEGLTADRFR
DLVRQVLPLAASWPESLPEPRRQALRLPSRSDALIAIHHPDDQHTLQSARRRLVFDEFLLLQLGLLKRRAELRSCSAPVL
QTAGQRDGLVARFLELLPFPLTGAQQRVLREIEADLVLSEPMARLIQGDVGSGKTVVAIAALLTAVEAGWQGAFMAPTEV
LAEQHYRTLCCWLPQLHVSVELLTGATTRIRRRQILDDLVNGSLKILVGTHALIEDPVAFSRLGLVVVDEQHRFGVKQRN
RLLNKGLQPHLLTMTATPIPRTLALSLHGDLDVSQIDELPPGRTPIQTQMIRGCDRDQAYQLIRDQVSRGQRAYVVLPLI
EDSEKLDLRSAVKVHSHLSEQVFAEFTVGLLHGRLSSSEKQGVIQSFAAGECQVLVSTTVVEVGVDVPQASVMVIDHADR
FGLAQLHQLRGRVGRGAAASHCVLINDSTNPLARQRLEVLVRSSDGFEIAEIDLRLRGPGQVLGTKQSGLPDLALASLAD
DGSVLEEARDEAQRLLSDDPNLTDHSRLKELLEAQWKHLSGTAHLN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=683, Percent_Identity=41.8740849194729, Blast_Score=416, Evalue=1e-117,
Organism=Escherichia coli, GI1787357, Length=420, Percent_Identity=34.2857142857143, Blast_Score=232, Evalue=7e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 93453; Mature: 93453

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAEPFRQSSNQSTQGLSTDQLQHLLSWMRILQQALTLEAENGFKNLEGRQENFHAFLVR
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
QLAEPPSGLLPTKSQARLSQLAEAFASYPDSSESARRRLVTDSRQLLHGIRQGLEPPAPI
HHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPPRLKQGEAERQRQMPLPSGNRSLKLESPLSEVKGIGPKLAERLAGLGLLLVKDLLQYY
CCCCCCCCHHHHHHCCCCCCCCCCEEECCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHC
PRDYVDYSSLRRIQALEAGEAATIVATVRRCHGFTSPRNPNLSILELQLQDPTGRLKVRR
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHH
FFAGRRFSSPAYLKSQSRLYPPGVTVAVSGLVKGGPYGMSFQDPLIEVMESPHSPLRSQS
HHHCCCCCCCHHHCCCCCCCCCCHHEEEHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHH
IGRLLPVYALTEGLTADRFRDLVRQVLPLAASWPESLPEPRRQALRLPSRSDALIAIHHP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCCCCCCCEEEEECC
DDQHTLQSARRRLVFDEFLLLQLGLLKRRAELRSCSAPVLQTAGQRDGLVARFLELLPFP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHCCCC
LTGAQQRVLREIEADLVLSEPMARLIQGDVGSGKTVVAIAALLTAVEAGWQGAFMAPTEV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
LAEQHYRTLCCWLPQLHVSVELLTGATTRIRRRQILDDLVNGSLKILVGTHALIEDPVAF
HHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHCCHHH
SRLGLVVVDEQHRFGVKQRNRLLNKGLQPHLLTMTATPIPRTLALSLHGDLDVSQIDELP
HHCCEEEECCHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHCCC
PGRTPIQTQMIRGCDRDQAYQLIRDQVSRGQRAYVVLPLIEDSEKLDLRSAVKVHSHLSE
CCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
QVFAEFTVGLLHGRLSSSEKQGVIQSFAAGECQVLVSTTVVEVGVDVPQASVMVIDHADR
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCEEEEEECCCC
FGLAQLHQLRGRVGRGAAASHCVLINDSTNPLARQRLEVLVRSSDGFEIAEIDLRLRGPG
CCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
QVLGTKQSGLPDLALASLADDGSVLEEARDEAQRLLSDDPNLTDHSRLKELLEAQWKHLS
CEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
GTAHLN
CCCCCC
>Mature Secondary Structure
MVAEPFRQSSNQSTQGLSTDQLQHLLSWMRILQQALTLEAENGFKNLEGRQENFHAFLVR
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
QLAEPPSGLLPTKSQARLSQLAEAFASYPDSSESARRRLVTDSRQLLHGIRQGLEPPAPI
HHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GPPRLKQGEAERQRQMPLPSGNRSLKLESPLSEVKGIGPKLAERLAGLGLLLVKDLLQYY
CCCCCCCCHHHHHHCCCCCCCCCCEEECCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHC
PRDYVDYSSLRRIQALEAGEAATIVATVRRCHGFTSPRNPNLSILELQLQDPTGRLKVRR
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHH
FFAGRRFSSPAYLKSQSRLYPPGVTVAVSGLVKGGPYGMSFQDPLIEVMESPHSPLRSQS
HHHCCCCCCCHHHCCCCCCCCCCHHEEEHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHH
IGRLLPVYALTEGLTADRFRDLVRQVLPLAASWPESLPEPRRQALRLPSRSDALIAIHHP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHCCCCCCCCEEEEECC
DDQHTLQSARRRLVFDEFLLLQLGLLKRRAELRSCSAPVLQTAGQRDGLVARFLELLPFP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHCCCC
LTGAQQRVLREIEADLVLSEPMARLIQGDVGSGKTVVAIAALLTAVEAGWQGAFMAPTEV
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
LAEQHYRTLCCWLPQLHVSVELLTGATTRIRRRQILDDLVNGSLKILVGTHALIEDPVAF
HHHHHHHHHHHHHHHHHHEEEEHHCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHCCHHH
SRLGLVVVDEQHRFGVKQRNRLLNKGLQPHLLTMTATPIPRTLALSLHGDLDVSQIDELP
HHCCEEEECCHHHCCHHHHHHHHHCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHCCC
PGRTPIQTQMIRGCDRDQAYQLIRDQVSRGQRAYVVLPLIEDSEKLDLRSAVKVHSHLSE
CCCCCHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHH
QVFAEFTVGLLHGRLSSSEKQGVIQSFAAGECQVLVSTTVVEVGVDVPQASVMVIDHADR
HHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEHHHHHHCCCCCCCEEEEEECCCC
FGLAQLHQLRGRVGRGAAASHCVLINDSTNPLARQRLEVLVRSSDGFEIAEIDLRLRGPG
CCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCC
QVLGTKQSGLPDLALASLADDGSVLEEARDEAQRLLSDDPNLTDHSRLKELLEAQWKHLS
CEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
GTAHLN
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]