Click here to switch to the map view.

The map label for this gene is tsf

Identifier: 124023367

GI number: 124023367

Start: 1453337

End: 1453993

Strand: Direct

Name: tsf

Synonym: P9303_16651

Alternate gene names: 124023367

Gene position: 1453337-1453993 (Clockwise)

Preceding gene: 124023366

Following gene: 124023368

Centisome position: 54.17

GC content: 50.84

Gene sequence:

>657_bases
ATGGCGGACGTATCAGCCAAGCTTGTCAAGGACCTGCGCGACAAGACCGGCGCGGGAATGATGGACTGCAAGAAAGCCCT
TGCAGAGAGTGACGGAGATATGATCAAGGCGAGCGAATGGCTGCGTAAGAAGGGTATTGCCAGTGCAGAAAAGAAATCTT
CTCGCATTGCTGCTGAAGGTGCCATTGGTACTTACATCCACACCGGAGCCAGGGTCGGGGTACTTCTGGAGTTGAACTGC
GAAACTGATTTTGTTGCTCGTGGTGATTTGTTCCAAGGGCTTTTAAAAGATGTCGCTATGCAAGTGGCGGCCTGCCCGAA
TGTCGAATACGTGTCCACAGAAGAGATTCCTGTTGATGTCGTTGAAAAGGAAAAATCTATTGAGATGGGGCGCGATGATC
TTTCTGGCAAGCCTGAACAGATGAAGGCAAAGATCGTTGAAGGACGAATTGGCAAGCGCCTTAAGGAACTGGTCTTGCTT
GAGCAACCCTTTATCCGTGACAGCTCCATGACGGTCGCGGAACTCGTCAAGCAAGTTGCTGGCAAGATTGGAGAGAATGT
CCAGGTTCGCCGCTTCACCCGATACACACTTGGGGAGGGGATTGAAGTGGACCAGACTGATTTCGCTACGGAAGTAGCAT
CCATGAAGACTGCTTAA

Upstream 100 bases:

>100_bases
GACGACAACGACGATTGAGTCCATTTACAGCACTAAGTTCTCGCCGCCGTCCTCCTTATCTGGTCGGCTGCATCCCTAAT
ACTCCTCACCCCGATTACCC

Downstream 100 bases:

>100_bases
TTTTGGCTGCGGAGAAGTAGATATTGCAACGCTTCGAGCCCGATCAGCAGATTGCCTCACTAAAAAAGCAGAGTCAGCGC
TTGTCGCTGACTCTGTACCA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MADVSAKLVKDLRDKTGAGMMDCKKALAESDGDMIKASEWLRKKGIASAEKKSSRIAAEGAIGTYIHTGARVGVLLELNC
ETDFVARGDLFQGLLKDVAMQVAACPNVEYVSTEEIPVDVVEKEKSIEMGRDDLSGKPEQMKAKIVEGRIGKRLKELVLL
EQPFIRDSSMTVAELVKQVAGKIGENVQVRRFTRYTLGEGIEVDQTDFATEVASMKTA

Sequences:

>Translated_218_residues
MADVSAKLVKDLRDKTGAGMMDCKKALAESDGDMIKASEWLRKKGIASAEKKSSRIAAEGAIGTYIHTGARVGVLLELNC
ETDFVARGDLFQGLLKDVAMQVAACPNVEYVSTEEIPVDVVEKEKSIEMGRDDLSGKPEQMKAKIVEGRIGKRLKELVLL
EQPFIRDSSMTVAELVKQVAGKIGENVQVRRFTRYTLGEGIEVDQTDFATEVASMKTA
>Mature_217_residues
ADVSAKLVKDLRDKTGAGMMDCKKALAESDGDMIKASEWLRKKGIASAEKKSSRIAAEGAIGTYIHTGARVGVLLELNCE
TDFVARGDLFQGLLKDVAMQVAACPNVEYVSTEEIPVDVVEKEKSIEMGRDDLSGKPEQMKAKIVEGRIGKRLKELVLLE
QPFIRDSSMTVAELVKQVAGKIGENVQVRRFTRYTLGEGIEVDQTDFATEVASMKTA

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084500, Length=151, Percent_Identity=34.4370860927152, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI291084498, Length=100, Percent_Identity=42, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI291084502, Length=100, Percent_Identity=42, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI171846268, Length=100, Percent_Identity=42, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786366, Length=163, Percent_Identity=41.1042944785276, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17561440, Length=202, Percent_Identity=27.2277227722772, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19921466, Length=113, Percent_Identity=38.9380530973451, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_PROM3 (A2CA99)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001017674.1
- ProteinModelPortal:   A2CA99
- SMR:   A2CA99
- STRING:   A2CA99
- GeneID:   4777329
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_16651
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   NVEYVSI
- ProtClustDB:   PRK12332
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 23800; Mature: 23669

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVSAKLVKDLRDKTGAGMMDCKKALAESDGDMIKASEWLRKKGIASAEKKSSRIAAEG
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
AIGTYIHTGARVGVLLELNCETDFVARGDLFQGLLKDVAMQVAACPNVEYVSTEEIPVDV
CHHHHEECCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHH
VEKEKSIEMGRDDLSGKPEQMKAKIVEGRIGKRLKELVLLEQPFIRDSSMTVAELVKQVA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GKIGENVQVRRFTRYTLGEGIEVDQTDFATEVASMKTA
HHHCCCCEEHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ADVSAKLVKDLRDKTGAGMMDCKKALAESDGDMIKASEWLRKKGIASAEKKSSRIAAEG
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCC
AIGTYIHTGARVGVLLELNCETDFVARGDLFQGLLKDVAMQVAACPNVEYVSTEEIPVDV
CHHHHEECCCEEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHH
VEKEKSIEMGRDDLSGKPEQMKAKIVEGRIGKRLKELVLLEQPFIRDSSMTVAELVKQVA
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GKIGENVQVRRFTRYTLGEGIEVDQTDFATEVASMKTA
HHHCCCCEEHHHHHHHCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA