Click here to switch to the map view.

The map label for this gene is pqqL [C]

Identifier: 124023359

GI number: 124023359

Start: 1446307

End: 1447503

Strand: Reverse

Name: pqqL [C]

Synonym: P9303_16571

Alternate gene names: 124023359

Gene position: 1447503-1446307 (Counterclockwise)

Preceding gene: 124023373

Following gene: 124023358

Centisome position: 53.96

GC content: 52.13

Gene sequence:

>1197_bases
ATGCCAGATGCACCTCTGACTTGTTTAGACCTCTGGTGCAAAGCAGGTAGTTCAAGCGAACAAAAAGGAGAGGAAGGACT
AGCCCACTTTCTTGAACACATGGTGTTCAAGGGAAGCTCACAGATGGAGGCTGGAGAATTCGATCGGAAAATCGAAGCGC
TTGGAGGCAGCAGCAATGCCGCCACAGGTTTCGATGACGTGCACTTTCACGTTCTTGTACCACCAACGGCAGCCAGGGCA
GCACTTGATCTACTACTCAATCTCGTTCTGACTCCAGCTCTGCGTTCAGAGGCCTATGCCATGGAGCGAGATGTCGTATT
GGAGGAAATTGCCCAATATCGAGATCAACCGGATGATCAAGTCCTCCAACAGCTTCTCGAAGCATGCTGCGAAGATCATC
CCTACGGCCGAGCCATCCTTGGCTTTGAAGCAAGCCTAAAAATAAGTACTCCCGAGCAAATGAGGGAGTTCCACAGCCGC
CGCTATCGAGGCCCGAACTGTTGCCTAGCAATTGCGGGTGCCATTCCTATAGGCCTCGAAGAAATCTTGAACAACAGCCG
TCTGGCTGAGTTAAATCACCAAACGATGGAGGACATTGATCCTGCCATTTCTCCAACTCTCAGCTTCCAAAAAGGGCGAC
GAGAGATTCAAGTCCCCAGGCTGGAATCCACCCGACTATTGATGACCTGGCCGATGCCCCCTGCCTCAAACCAAGAGATG
GTGATGGGAGCTGACCTGGCGACCACCCTGCTTGCGGAAGGACGTCGCAGTCGACTGGTGCATCACCTCAGAGAGGAATT
GCAAATCGTGGAATCGATCGATATGGATGTAACCGTGTTGGAACAAGGCAGCCTTGTATTGCTAGAAGCATGCTGCAACG
AGAAGCAGCTGGACAGGGTGGAAAAGGAAATCCACCATTTACTGCAGACCAGCCTCGAATCAACACCCAAGAATCAAGAG
ATCGAACGAGCTAGCCAACTGGTTTCAAATGGACTGTGTTTCAGCCTTGAAGCTCCCAGTCAAGTAGCCGGCCTGGCAGG
GAATCAAGCTCTTTGGAATCGTCCTCAATCCTTGTTGGCACCACTTGATCACCTGCCTGCATGGACGCCGACTCGACTTC
TCGAGCAAATGCTTCCATTGCTGCAACCAGAGCGCAGCTTCACCCTTGTTGCCAGACCGATGGAAGCAGGCGAATGA

Upstream 100 bases:

>100_bases
CAGAATGGGACTTTGACACGCACCTCTGACACGCTCCACCCCTAAACCCAATCTTCAACACTGGGCTCTAAACAACAAGA
CCCGCTGCGTGGTGGCATCC

Downstream 100 bases:

>100_bases
ATCCTCTTGATGTGGTTTTAGATCCAATCGCCGCACCGGGAGTTATTGCCGCCAAGCTCTGGGTTAGAGGCGGTAGTGGT
GCTGACCCAAAAGGGCAACG

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNAATGFDDVHFHVLVPPTAARA
ALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQVLQQLLEACCEDHPYGRAILGFEASLKISTPEQMREFHSR
RYRGPNCCLAIAGAIPIGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPASNQEM
VMGADLATTLLAEGRRSRLVHHLREELQIVESIDMDVTVLEQGSLVLLEACCNEKQLDRVEKEIHHLLQTSLESTPKNQE
IERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLAPLDHLPAWTPTRLLEQMLPLLQPERSFTLVARPMEAGE

Sequences:

>Translated_398_residues
MPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNAATGFDDVHFHVLVPPTAARA
ALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQVLQQLLEACCEDHPYGRAILGFEASLKISTPEQMREFHSR
RYRGPNCCLAIAGAIPIGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPASNQEM
VMGADLATTLLAEGRRSRLVHHLREELQIVESIDMDVTVLEQGSLVLLEACCNEKQLDRVEKEIHHLLQTSLESTPKNQE
IERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLAPLDHLPAWTPTRLLEQMLPLLQPERSFTLVARPMEAGE
>Mature_397_residues
PDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNAATGFDDVHFHVLVPPTAARAA
LDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQVLQQLLEACCEDHPYGRAILGFEASLKISTPEQMREFHSRR
YRGPNCCLAIAGAIPIGLEEILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPASNQEMV
MGADLATTLLAEGRRSRLVHHLREELQIVESIDMDVTVLEQGSLVLLEACCNEKQLDRVEKEIHHLLQTSLESTPKNQEI
ERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLAPLDHLPAWTPTRLLEQMLPLLQPERSFTLVARPMEAGE

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=170, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI46593007, Length=201, Percent_Identity=23.8805970149254, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI156071450, Length=282, Percent_Identity=26.241134751773, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=167, Percent_Identity=23.9520958083832, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=175, Percent_Identity=29.1428571428571, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21357875, Length=172, Percent_Identity=27.3255813953488, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24646943, Length=172, Percent_Identity=27.3255813953488, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667786, Length=376, Percent_Identity=23.6702127659574, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641429, Length=285, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 44248; Mature: 44117

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNA
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
ATGFDDVHFHVLVPPTAARAALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQ
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VLQQLLEACCEDHPYGRAILGFEASLKISTPEQMREFHSRRYRGPNCCLAIAGAIPIGLE
HHHHHHHHHHCCCCCCCEEEECCCEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCCCHH
EILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPASNQEM
HHHCCCHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCE
VMGADLATTLLAEGRRSRLVHHLREELQIVESIDMDVTVLEQGSLVLLEACCNEKQLDRV
EECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEHHHCCHHHHHHH
EKEIHHLLQTSLESTPKNQEIERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHCCCCHHHHCCCHHHHH
PLDHLPAWTPTRLLEQMLPLLQPERSFTLVARPMEAGE
HHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
PDAPLTCLDLWCKAGSSSEQKGEEGLAHFLEHMVFKGSSQMEAGEFDRKIEALGGSSNA
CCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
ATGFDDVHFHVLVPPTAARAALDLLLNLVLTPALRSEAYAMERDVVLEEIAQYRDQPDDQ
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VLQQLLEACCEDHPYGRAILGFEASLKISTPEQMREFHSRRYRGPNCCLAIAGAIPIGLE
HHHHHHHHHHCCCCCCCEEEECCCEEEECCHHHHHHHHHHHCCCCCCEEEECCCCCCCHH
EILNNSRLAELNHQTMEDIDPAISPTLSFQKGRREIQVPRLESTRLLMTWPMPPASNQEM
HHHCCCHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCE
VMGADLATTLLAEGRRSRLVHHLREELQIVESIDMDVTVLEQGSLVLLEACCNEKQLDRV
EECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEHHHCCHHHHHHH
EKEIHHLLQTSLESTPKNQEIERASQLVSNGLCFSLEAPSQVAGLAGNQALWNRPQSLLA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHCCCCHHHHCCCHHHHH
PLDHLPAWTPTRLLEQMLPLLQPERSFTLVARPMEAGE
HHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA