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The map label for this gene is trpD [H]

Identifier: 124023278

GI number: 124023278

Start: 1379931

End: 1381043

Strand: Direct

Name: trpD [H]

Synonym: P9303_15761

Alternate gene names: 124023278

Gene position: 1379931-1381043 (Clockwise)

Preceding gene: 124023270

Following gene: 124023279

Centisome position: 51.44

GC content: 57.23

Gene sequence:

>1113_bases
GTGTTGTCCCCATCACCCAGCCCGGAGTGCTTCGCACCCGGGTTTTTTTCTGCTCCGATGCCTACTTCAGCTATTGCCTC
TCCCTCTTGGTCGCAAATCCTCGAGATGTTGCTCGAGGGACAAAACCTGCCCGAGGTGGAAGCAACTGCCTTGATGGAGG
CTTGGTTGGCGGAACAACTAACCCCTGTGCAGACAGGTGCGTTTCTAGCAGCTTTGCGAGCCAAGGGGGTAACCGGAAGT
GAGTTGTCAGGCATGGCCCAGGTGTTGCGAGGTGCTTGTCCCTTGCCTTGCCCATTGCCAGGCATCCCTATGGTCGACAC
CTGTGGAACAGGTGGCGACGGTGCAGATACCTTCAACATCTCAACCGCAGTGGCGTTTACTGCTGCCGCCTGCGGGGCGA
ATGTGGCTAAGCATGGCAATCGCAGTGCAAGTGGCAAAGTCGGTTCAGCAGATGTTCTCGAGGGCCTGGGTCTGCAGCTC
AAGGCTCCTCTTGTCTCTGTGGTGGAGGCCCTGGCTGAGGTACGCGTCACATTTTTGTTTGCCCCGGCCTGGCACCCCGC
TTTGGTCAACTTGGCCCCGTTGCGGCGCAGCCTTGGAGTGCGCACCGTGTTCAATCTTCTAGGTCCACTGGTGAATCCTT
TACAACCGAATGCCCAAGTTCTCGGGGTAGCTAAGGCTGAGCTGCTCAATCCAATGGCGGAAGCATTGCAACGGCTTGGC
TTGCAGCGGGCCGTTGTTGTCCATGGCGCCGGTGGCCTTGATGAAGCGTCGTTGGAGGGAGTCAATGCAATGCGTTTGCT
TGAGGATGGTCATGTGCGACAAGCATCGATCGATTCGGCAGAACTCGGGCTTACTAGAGCTCCTTTGCAGGCTCTCCAGG
GGGGTGATTTGGCAACAAATCAAGCGATTCTTTCCGCTGTACTTCAGGGAGGCGGCACCGCCCCTCAAAGGGATGTGGTG
GCATTGAACACAGCCCTAGTGCTCTGGGCTGCTGGCCTACAAGATGATTTACGAGCAGGTGTTTCTGCTGCAAAGACTTG
CCTGCAGGAGGGCCTCCCCTGGCAGCGGCTAGAAGGGCTCCGCATGGCACTTGATCATCAAATTGGAGAATGA

Upstream 100 bases:

>100_bases
TCCTATCCAGCTTCGATAGCGCCGTTTGGATGGATCAGAGTTCTTTCTTGCTGTTCTCTTGTAGAGATTCTCGCCAGTAG
CAAAGTTTTAGGGGATAGTG

Downstream 100 bases:

>100_bases
GACTGCGATGACTTCGGGATCCTTCTGCTGATGATTGCTTCATCGCGAAATTCGGCGCTCTTGGTGCTTGCTGATGGCAC
GGTGCTTGAGGGGGAGGCCT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MLSPSPSPECFAPGFFSAPMPTSAIASPSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTGS
ELSGMAQVLRGACPLPCPLPGIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQL
KAPLVSVVEALAEVRVTFLFAPAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLG
LQRAVVVHGAGGLDEASLEGVNAMRLLEDGHVRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDVV
ALNTALVLWAAGLQDDLRAGVSAAKTCLQEGLPWQRLEGLRMALDHQIGE

Sequences:

>Translated_370_residues
MLSPSPSPECFAPGFFSAPMPTSAIASPSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTGS
ELSGMAQVLRGACPLPCPLPGIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQL
KAPLVSVVEALAEVRVTFLFAPAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLG
LQRAVVVHGAGGLDEASLEGVNAMRLLEDGHVRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDVV
ALNTALVLWAAGLQDDLRAGVSAAKTCLQEGLPWQRLEGLRMALDHQIGE
>Mature_370_residues
MLSPSPSPECFAPGFFSAPMPTSAIASPSWSQILEMLLEGQNLPEVEATALMEAWLAEQLTPVQTGAFLAALRAKGVTGS
ELSGMAQVLRGACPLPCPLPGIPMVDTCGTGGDGADTFNISTAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQL
KAPLVSVVEALAEVRVTFLFAPAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLG
LQRAVVVHGAGGLDEASLEGVNAMRLLEDGHVRQASIDSAELGLTRAPLQALQGGDLATNQAILSAVLQGGGTAPQRDVV
ALNTALVLWAAGLQDDLRAGVSAAKTCLQEGLPWQRLEGLRMALDHQIGE

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=329, Percent_Identity=40.4255319148936, Blast_Score=204, Evalue=7e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=324, Percent_Identity=28.7037037037037, Blast_Score=106, Evalue=7e-24,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 38149; Mature: 38149

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSPSPSPECFAPGFFSAPMPTSAIASPSWSQILEMLLEGQNLPEVEATALMEAWLAEQL
CCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
TPVQTGAFLAALRAKGVTGSELSGMAQVLRGACPLPCPLPGIPMVDTCGTGGDGADTFNI
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEH
STAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQLKAPLVSVVEALAEVRVTFLF
HHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHEEE
APAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHCC
LQRAVVVHGAGGLDEASLEGVNAMRLLEDGHVRQASIDSAELGLTRAPLQALQGGDLATN
CCEEEEEECCCCCCHHHHCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHCCCCCHHH
QAILSAVLQGGGTAPQRDVVALNTALVLWAAGLQDDLRAGVSAAKTCLQEGLPWQRLEGL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
RMALDHQIGE
HHHHHHHCCC
>Mature Secondary Structure
MLSPSPSPECFAPGFFSAPMPTSAIASPSWSQILEMLLEGQNLPEVEATALMEAWLAEQL
CCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
TPVQTGAFLAALRAKGVTGSELSGMAQVLRGACPLPCPLPGIPMVDTCGTGGDGADTFNI
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEH
STAVAFTAAACGANVAKHGNRSASGKVGSADVLEGLGLQLKAPLVSVVEALAEVRVTFLF
HHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHCCCCEECCHHHHHHHHHHHHHHHEEE
APAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLQPNAQVLGVAKAELLNPMAEALQRLG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHHHHHHCC
LQRAVVVHGAGGLDEASLEGVNAMRLLEDGHVRQASIDSAELGLTRAPLQALQGGDLATN
CCEEEEEECCCCCCHHHHCCHHHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHCCCCCHHH
QAILSAVLQGGGTAPQRDVVALNTALVLWAAGLQDDLRAGVSAAKTCLQEGLPWQRLEGL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
RMALDHQIGE
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]